Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Henri Voedts"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
β-lactam-induced bacterial killing is complex and not fully resolved. Authors carry out a genome-wide analysis, through penicillin-binding protein replacement, to identify genes essential for drug efficacy.
Externí odkaz:
https://doaj.org/article/cb6efd426f0747438396c3f0af0e152d
Autor:
Nathanael A. Caveney, Guillermo Caballero, Henri Voedts, Ana Niciforovic, Liam J. Worrall, Marija Vuckovic, Matthieu Fonvielle, Jean-Emmanuel Hugonnet, Michel Arthur, Natalie C. J. Strynadka
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In E. coli, alternate peptidoglycan crosslinking reactions carried out by the L,D-transpeptidase YcbB can lead to beta-lactam resistance. Here, Caveney et al. solve the crystal structure of YcbB and shed light into its mechanism of action and into Yc
Externí odkaz:
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a
Autor:
Waldemar Vollmer, Henri Voedts, Adam Lodge, Jean-Emmanuel Hugonnet, Delphine Dorchêne, Michel Arthur
Publikováno v:
EMBO J
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (19), ⟨10.15252/embj.2021108126⟩
EMBO Journal
EMBO Journal, EMBO Press, 2021, 40 (19), ⟨10.15252/embj.2021108126⟩
Bacteria resist to the turgor pressure of the cytoplasm through a net-like macromolecule, the peptidoglycan, made of glycan strands connected via peptides cross-linked by penicillin-binding proteins (PBPs). We recently reported the emergence of β-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f3ca90e046e0e9a8bedc98e139959b
https://europepmc.org/articles/PMC8488565/
https://europepmc.org/articles/PMC8488565/
Autor:
Michel Arthur, G. Caballero, Natalie C. J. Strynadka, Nathanael A. Caveney, Ana P. Niciforovic, Liam J. Worrall, Jean-Emmanuel Hugonnet, Matthieu Fonvielle, Marija Vuckovic, Henri Voedts
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
The bacterial cell wall plays a crucial role in viability and is an important drug target. In Escherichia coli, the peptidoglycan crosslinking reaction to form the cell wall is primarily carried out by penicillin-binding proteins that catalyse D,D-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375fbbcd034cb83e64d154162fa96617
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a
https://doaj.org/article/5893b624e29f4e1b9969ad99f17cd15a
Publikováno v:
Nature Communications; 12/27/2022, Vol. 13 Issue 1, p1-14, 14p
Autor:
Voedts, Henri, Dorchêne, Delphine, Lodge, Adam, Vollmer, Waldemar, Arthur, Michel, Hugonnet, Jean‐Emmanuel
Publikováno v:
EMBO Journal; Oct2021, Vol. 40 Issue 19, p1-19, 19p
Publikováno v:
Drug Week; 3/31/2023, p1586-1586, 1p
Autor:
Caveney, Nathanael A., Caballero, Guillermo, Voedts, Henri, Niciforovic, Ana, Worrall, Liam J., Vuckovic, Marija, Fonvielle, Matthieu, Hugonnet, Jean-Emmanuel, Arthur, Michel, Strynadka, Natalie C. J.
Publikováno v:
Nature Communications; 4/23/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p