Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Henri Van Mechelen"'
Publikováno v:
European Journal of Clinical Investigation. 28:798-806
BACKGROUND: As endothelin-1 exerts positive inotropic effects, the present study evaluated whether the hypotensive effects of the endothelin-1 receptor antagonist bosentan were partially related to a decrease in myocardial performance. METHODS: In gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ff8c00b1a0404b8a8360fbc8233994e
https://doi.org/10.1046/j.1365-2362.1998.00374.x
https://doi.org/10.1046/j.1365-2362.1998.00374.x
Autor:
Julian Donckier, PE Massart, Henri Van Mechelen, Guy R. Heyndrickx, André A. Charlier, Jean-Marie Ketelslegers, Dominique Hodeige
Publikováno v:
Journal of Hypertension. 16:835-841
OBJECTIVE: To evaluate whether the cumulative hypotensive effect of the endothelin-1 receptor antagonist bosentan, previously demonstrated in the presence of an angiotensin converting enzyme inhibitor, persists under angiotensin II receptor blockade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679c0be64e2ad4f505cb84c52a1eff3a
https://doi.org/10.1097/00004872-199816060-00015
https://doi.org/10.1097/00004872-199816060-00015
Autor:
Jean-Marie Ketelslegers, André A. Charlier, PE Massart, Henri Van Mechelen, Olivier Laloux, Jean-Paul Clozel, Julian Donckier, Dominique Hodeige, Guy R. Heyndrickx
Publikováno v:
Circulation. 96:1250-1256
Background Endothelin-1 (ET-1) may play a role in hypertension. ET-1 receptor antagonism by bosentan lowers blood pressure in hypertension. We evaluated whether the effect of bosentan is still observed under ACE inhibitors (ACEI). Methods and Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4577f29b144e94263fb457cbe6b8e0
https://doi.org/10.1161/01.cir.96.4.1250
https://doi.org/10.1161/01.cir.96.4.1250
Autor:
Laurence Galanti, W. Hayashida, Julian Donckier, Philippe L. Selvais, L. Stoleru, Jean-Marie Ketelslegers, Jean-Paul Clozel, Hubert Pouleur, Henri Van Mechelen
Publikováno v:
Circulation. 92:106-113
Background Endothelin-1, a vasoconstrictive peptide released by endothelium, may be involved in the pathophysiology of hypertension. The goal of the present study was to evaluate the role of endogenous endothelin-1 in renal hypertension in dogs. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de4cfc897b30fb66dc6ccb415ad9e1c
https://doi.org/10.1161/01.cir.92.1.106
https://doi.org/10.1161/01.cir.92.1.106
Autor:
W. Hayashida, Julian Donckier, L. Stoleru, Henri Van Mechelen, André Keyeux, Laurence Galanti, Hubert Pouleur, Claude Hanet, Jean-Marie Ketelslegers
Publikováno v:
Journal of Cardiovascular Pharmacology. 2:212-219
We assess hemodynamic, vascular, and hormonal effects of endothelin-1 (ET-1) at pathophysiologic levels on normal and ischemic myocardium. Thirty conscious chronically instrumented dogs were studied before, during, and after a 10-min coronary artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745dcc2de302704f139158b859a95d0f
https://doi.org/10.1097/00005344-199411000-00006
https://doi.org/10.1097/00005344-199411000-00006
Publikováno v:
The American journal of physiology. 274(2)
We studied effects of enalaprilat and L-158,809, an angiotensin II type-1 receptor antagonist, on left ventricular (LV) diastolic relaxation in 11 normal control dogs and 16 LV hypertrophied (LVH) dogs with perinephritic hypertension. At baseline, LV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1856b2e5fc3eee685f101c4c2c2d3f0
https://pubmed.ncbi.nlm.nih.gov/9486265
https://pubmed.ncbi.nlm.nih.gov/9486265
Publikováno v:
Cardiovascular research. 33(1)
OBJECTIVE: Angiotensin II has been suggested to be involved in the pathogenesis of diastolic dysfunction in left ventricular hypertrophy (LVH). The purpose of this study was to asses the effects of enalaprilat and L-158,809, an angiotensin II type-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfc277f8cfc05964a720f209e4c738a
https://pubmed.ncbi.nlm.nih.gov/9059528
https://pubmed.ncbi.nlm.nih.gov/9059528
Autor:
N. R. Musso, Hubert Pouleur, G. Lotti, Michel F. Rousseau, Christian van Eyll, J. Raigoso, Henri Van Mechelen
Publikováno v:
Journal of cardiovascular pharmacology. 19(2)
Twenty-six patients with mild to moderate heart failure were studied to determine the effects of epinine infusion (at a rate producing plasma levels similar to those measured after oral administration of 100 mg of the prodrug ibopamine) on left ventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1e6344b357e63a92bf738eb5d55dec
https://pubmed.ncbi.nlm.nih.gov/1376782
https://pubmed.ncbi.nlm.nih.gov/1376782
Autor:
André A. Charlier, Hubert Pouleur, André Keyeux, J. Raigoso, Henri Van Mechelen, Erwin Schröder
Publikováno v:
Journal of the American College of Cardiology. 16(7)
To determine if alterations in regional coronary vascular resistance could occur in the type of myocardial ischemia present in severe angina pectoris, regional perfusion and function were studied in 35 conscious sedated dogs. A stenosis producing sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57fb76079ca595316703e62a531142a
https://pubmed.ncbi.nlm.nih.gov/2254562
https://pubmed.ncbi.nlm.nih.gov/2254562
Publikováno v:
Journal of the American College of Cardiology. 15:A30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d9b6d7c3f321e5422c695dd34b11e9
https://doi.org/10.1016/0735-1097(90)91842-i
https://doi.org/10.1016/0735-1097(90)91842-i