Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Henri Moereels"'
Autor:
Henri Moereels, Lydie Meheus, Hans Pottel, Karsten Conrad, Ann Union, Filip De Keyser, Guy Serre, Guenter Steiner, René Louis Humbel
Publikováno v:
Arthritis & Rheumatism. 46:1185-1195
Objective To identify immunodominant epitopes in natural filaggrin that are reactive with antifilaggrin autoantibodies (AFA) in the sera of patients with rheumatoid arthritis (RA) and to explore their use in a diagnostic assay format. Methods Based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219856c22284ddcab841c26631f414b0
https://doi.org/10.1002/art.10229
https://doi.org/10.1002/art.10229
Publikováno v:
Scopus-Elsevier
The hepatitis C virus (HCV) glycoproteins E1 and E2 should be anchored in the viral membrane by their C-terminal domains. During synthesis, they are translocated to the endoplasmic reticulum (ER) lumen where they remain. The 31 C-terminal residues of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36a65880d6065d844da5378592a1d3b
https://doi.org/10.1128/jvi.76.4.1944-1958.2002
https://doi.org/10.1128/jvi.76.4.1944-1958.2002
Publikováno v:
Letters in Peptide Science. 5:139-142
With the use of the binmap method, 154 G-protein-coupled peptide receptors are classified. The binmap coordinates are obtained by using the number of residues between the conserved N residue in TM1 and C in the TM4-TM5 loop, between this C and the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e125a8d86a4e9fed6d92a10743084e8
https://doi.org/10.1007/bf02443456
https://doi.org/10.1007/bf02443456
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 53:191-197
In a previous study (Vanden Bossche et al., Breast Cancer Res. Treat. 30 (1994) 43) the interaction between (+)-S-vorozole and the I-helix of cytochrome P450 19 (P450 aromatase) has been reported. In the present study we extended the “I-helix model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49495cbfca5b669866557ade3266137
https://doi.org/10.1016/0960-0760(95)00033-v
https://doi.org/10.1016/0960-0760(95)00033-v
Autor:
P. A. J. Janssen, Christopher J. Michejda, S.H. Hughes, Y. Hsiou, Eddy Arnold, Arthur D. Clark, S Jessen, Jianping Ding, Kalyan Das, Rudi Pauwels, Xiaode Lu, Wanyi Zhang, Richard H. Smith, Chris Tantillo, Luc Koymans, Henri Moereels, Koenraad Jozef Lodewijk Marcel Andries, Alfredo Jacobo-Molina, M.Kroeger Koepke
Publikováno v:
Structure. 3:365-379
Background: HIV-1 reverse transcriptase (RT) is a multifunctional enzyme that copies the RNA genome of HIV-1 into DNA. It is a heterodimer composed of a 66 kDa (p66) and a 51 kDa (p51) subunit. HIV-1 RT is a crucial target for structure-based drug de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2813ef76a71bfcae3ecae25e4bff338a
https://doi.org/10.1016/s0969-2126(01)00168-x
https://doi.org/10.1016/s0969-2126(01)00168-x
Autor:
Henri Moereels, Joseph B. Moon, Gerald M. Maggiora, Michael S. Lajiness, Mark A. Johnson, Douglas C. Rohrer, James D. Petke, Peter Willett, Paul J. Lewi, Geoffrey M. Downs
Publikováno v:
Advanced Computer-Assisted Techniques in Drug Discovery, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::420fa7658cafdfb71ece651fdfd582e7
https://doi.org/10.1002/9783527615674.ch3
https://doi.org/10.1002/9783527615674.ch3
Autor:
Henri Moereels, Paul J. Lewi
Publikováno v:
TrAC Trends in Analytical Chemistry. 10:283-290
The linear sequences of amino acids of proteins can be compared for similarity or dissimilarity by means of computer algorithms. Here we focus on dissimilarities between 34 protein sequences belonging to the class of G-protein coupled receptors which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6561124c0aaa7c97bb8a8f3e633f5255
https://doi.org/10.1016/0165-9936(91)85006-d
https://doi.org/10.1016/0165-9936(91)85006-d
Publikováno v:
Journal of Computer-Aided Molecular Design. 4:131-145
Today, more than 40 protein amino acid (AA) sequences of membrane receptors coupled to guanine nucleotide binding proteins (G-proteins) are available. For those working in the field of medicinal chemistry, these sequences present a new type of inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aefb4f5918ffe06b59edcd14e50fc73
https://doi.org/10.1007/bf00125315
https://doi.org/10.1007/bf00125315
Autor:
Henri Moereels, J. Snoeks, P. A. J. Janssen, Leo Wouters, Pj Lewi, B. Dewindt, Koenraad Jozef Lodewijk Marcel Andries
Publikováno v:
Journal of Virology. 64:1117-1123
A variety of chemically different compounds inhibit the replication of several serotypes of rhinoviruses (common-cold viruses). We noticed that one of these antiviral compounds, WIN 51711, had an antiviral spectrum clearly distinctive from a consensu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6409f629807f930f36c444b5e943a695
https://doi.org/10.1128/jvi.64.3.1117-1123.1990
https://doi.org/10.1128/jvi.64.3.1117-1123.1990
Publikováno v:
Computer methods and programs in biomedicine. 56(3)
Unaligned amino acid sequences can be characterized by their composition of amino acid n-tuples (i.e. doublets, triplets, quadruplets, etc.). In this study we investigated the performance of two statistics, termed commonality and specificity, that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8959ced99aaae96c9b15e884c6d3a26b
https://pubmed.ncbi.nlm.nih.gov/9725648
https://pubmed.ncbi.nlm.nih.gov/9725648