Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Henri Magdelenat"'
Publikováno v:
McGill Journal of Medicine, Vol 1, Iss 2 (2020)
Programmed Cell Death (PCD) is a highly regulated but not yet fully understood process by which selective gene expression leads to cell demise. The term apoptosis refers to the typical morphological changes observed with PCD. In the present study, we
Externí odkaz:
https://doaj.org/article/08d1313e806a4e6192364287e5dfc65b
Publikováno v:
McGill Journal of Medicine, Vol 1, Iss 2 (2020)
Programmed Cell Death (PCD) is a highly regulated but not yet fully understood process by which selective gene expression leads to cell demise. The term apoptosis refers to the typical morphological changes observed with PCD. In the present study, we
Autor:
Klaus-Peter Janssen, Andreas Doll, Daniel Louvard, Miguel Abal, Henri Magdelenat, Rui Bras-Gonçalves, Sylvie Robine, Karine Boyé, Francesc Alameda, Jaume Reventós, Hafida Fsihi, Marie-France Poupon
Publikováno v:
Tumor Biology. 28:139-150
Hepatic and lung metastases are the leading causes of mortality and major indicators of aggressiveness in colorectal cancer. The underlying molecular mechanisms contributing to the development of metastasis are still unclear. Here, we designed a nove
Autor:
Bernard Asselain, Carine Tran-Perennou, Rosette Lidereau, Ivan Bièche, S. Vignaud, Véronique Becette, Henri Magdelenat, E Boudou, P. de Cremoux, F. Spyratos, Brigitte Sigal-Zafrani
Publikováno v:
Endocrine-Related Cancer. 11:489-495
Quantitative reverse transcription-polymerase chain reaction (RT-PCR) used to detect minor changes in specific mRNA concentrations may be associated with poor reproducibility. Stringent quality control is therefore essential at each step of the proto
Autor:
André Nicolas, Anne Vincent-Salomon, Jérôme Couturier, J.P. Thiery, Paul Fréneaux, A. Al Ghuzlan, Xavier Sastre-Garau, Henri Magdelenat, P. Genin, Christophe Rosty, Brigitte Sigal-Zafrani, Alexandra Rousseau
Publikováno v:
Histopathology. 45:142-147
To determine whether cell size is related to HER-2/neu status and/or to Akt activation in breast carcinomas. HER-2/neu overexpression is observed in 20-30% of invasive breast carcinomas with poor pronostic features, but little is known about the cell
Publikováno v:
Bioinformatics. 20:2562-2571
Motivation: Multiclass response (MCR) experiments are those in which there are more than two classes to be compared. In these experiments, though the null hypothesis is simple, there are typically many patterns of gene expression changes across the d
Autor:
Miguel Abal, Patricia de Cremoux, Marie-France Poupon, Sylvie Robine, Rui Bras-Gonçalves, Hafida Fsihi, Henri Magdelenat, Jean-Gabriel Judde, Daniel Louvard
Publikováno v:
Oncogene. 23:1737-1744
Mutations in the tumor-suppressor gene p53 have been associated with advanced colorectal cancer (CRC). Irinotecan (CPT-11), a DNA topoisomerase 1 inhibitor, has been recently incorporated to the adjuvant therapy. Since the DNA-damage checkpoint depen
Autor:
Claude Nos, C. Bonneton, Jean-Yves Pierga, Anne Vincent-Salomon, Nathalie Blin, Pierre Pouillart, Jean Paul Thiery, Patricia de Cremoux, Henri Magdelenat
Publikováno v:
Clinical Cancer Research. 10:1392-1400
Purpose: The presence of tumor cells in bone marrow has been reported to represent an important prognostic indicator in breast cancer, but the clinical significance of circulating cells in peripheral blood is less well known. The aim of this study wa
Autor:
Marianne Ziol, Marie-Cécile Vacher-Lavenu, Martine Thioux, Sylvain Labbé, Christelle Bouillac, Xavier Sastre-Garau, Isabelle Cartier, Joël Coste, Henri Magdelenat, Patricia de Cremoux, Béatrix Cochand-Priollet, Philippe Vielh, Anne Dosda, Vincent Molinié, Catherine Le Galès
Publikováno v:
American Journal of Clinical Pathology. 120:492-499
The aim of this study was to determine the efficiency of the Hybrid Capture 2 (HC2; Digene, Gaithersburg, MD) human papillomavirus (HPV) assay for the detection of cervical neoplasia. Of the 1,785 patients recruited, 462 (25.88%) were referred for co
Autor:
E Boudou, B L Brockdorff, Nils Brünner, Henri Magdelenat, P. de Cremoux, Carine Tran-Perennou, Anne E. Lykkesfeldt
Publikováno v:
Endocrine-related cancer. :409-418
Using a quantitative real-time RT-PCR technique we have compared the expression of a number of genes in two different human breast cancer model systems for development of acquired resistance to antiestrogens. The model system developed at the Danish