Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Henri M Spronk"'
Autor:
Bianca Dahlen, Andreas Schulz, Sebastian Göbel, Sven‐Oliver Tröbs, Sören Schwuchow‐Thonke, Henri M. Spronk, Jürgen H. Prochaska, Natalie Arnold, Karl J. Lackner, Tommaso Gori, Hugo tenCate, Thomas Münzel, Philipp S. Wild, Marina Panova‐Noeva
Publikováno v:
ESC Heart Failure, Vol 8, Iss 4, Pp 2991-3001 (2021)
Abstract Aims Platelet indices have been associated with traditional cardiovascular risk factors, cardiovascular diseases and all‐cause mortality. This study aimed to investigate the role of platelet count, mean platelet volume (MPV) and platelet
Externí odkaz:
https://doaj.org/article/28852a7ee85d4691a2427915490ee36d
Autor:
Magdalena L. Bochenek, Rajinikanth Gogiraju, Stefanie Großmann, Janina Krug, Jennifer Orth, Sabine Reyda, George S. Georgiadis, Henri M. Spronk, Stavros Konstantinides, Thomas Münzel, John H. Griffin, Philipp Wild, Christine Espinola-Klein, Wolfram Ruf, Katrin Schäfer
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Blood clot formation initiates ischemic events, but coagulation roles during postischemic tissue repair are poorly understood. The endothelial protein C receptor (EPCR) regulates coagulation, as well as immune and vascular signaling, by protease acti
Externí odkaz:
https://doaj.org/article/0909dcd5f8c44e619cf8af8d0733a288
Autor:
Steven P. Grover, Clare M. Schmedes, Alyson C. Auriemma, Emily Butler, Molly L. Parrish, Adam Miszta, Audrey C. Cleuren, Mayken Visser, Stefan Heitmeier, Jens J. Posma, Henri M. Spronk, Silvio Antoniak, Alisa S. Wolberg, Rafal Pawlinski, David Gailani, Nigel Mackman
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 207-216 (2020)
Abstract: The intrinsic tenase complex (FIXa-FVIIIa) of the intrinsic coagulation pathway and, to a lesser extent, thrombin-mediated activation of FXI, are necessary to amplify tissue factor (TF)-FVIIa–initiated thrombin generation. In this study,
Externí odkaz:
https://doaj.org/article/865ba4a864934f76b878406b948ce0ba
Autor:
Marina Panova-Noeva, Bianca Wagner, Markus Nagler, Thomas Koeck, Vincent ten Cate, Jürgen H. Prochaska, Stefan Heitmeier, Imke Meyer, Christoph Gerdes, Volker Laux, Stavros Konstantinides, Henri M. Spronk, Thomas Münzel, Karl J. Lackner, Kirsten Leineweber, Hugo ten Cate, Philipp S. Wild
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102978- (2020)
Background: The pathogenesis of arterial and venous thrombosis is in large part interlaced. How much platelet phenotype relates to acute venous thromboembolism (VTE) independent of the underlying cardiovascular profile is presently poorly investigate
Externí odkaz:
https://doaj.org/article/c6918c6348874a0d9a132c038083de14
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
Autor:
Birke J. Benedikter, Freek G. Bouwman, Alexandra C. A. Heinzmann, Tanja Vajen, Edwin C. Mariman, Emiel F. M. Wouters, Paul H. M. Savelkoul, Rory R. Koenen, Gernot G. U. Rohde, Rene van Oerle, Henri M. Spronk, Frank R. M. Stassen
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Airway epithelial cells secrete extracellular vesicles (EVs) under basal conditions and when exposed to cigarette smoke extract (CSE). Getting insights into the composition of these EVs will help unravel their functions in homeostasis and smoking-ind
Externí odkaz:
https://doaj.org/article/2e10a0f1e43948209df9eeb2724a1d44
Autor:
Lisa Eggebrecht, Jürgen H. Prochaska, Andreas Schulz, Natalie Arnold, Claus Jünger, Sebastian Göbel, Dagmar Laubert‐Reh, Harald Binder, Manfred E. Beutel, Nobert Pfeiffer, Stefan Blankenberg, Karl J. Lackner, Henri M. Spronk, Hugo ten Cate, Thomas Münzel, Philipp S. Wild
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 17 (2018)
Background Preclinical data have indicated a link between use of vitamin K antagonists (VKA) and detrimental effects on vascular structure and function. The objective of the present study was to determine the relationship between VKA intake and diffe
Externí odkaz:
https://doaj.org/article/2930d57bf8a84cb98d8947941d4d6345
Autor:
Isabelle C Van Gelder, Michiel Rienstra, Harry J G M Crijns, Henri M Spronk, Elton A M P Dudink, Ernaldo G Marcos, Ruben R De With
Publikováno v:
EP Europace, 22(3), 352-360. Oxford University Press
Europace, 22(3), 352-360. Oxford University Press
Europace, 22(3), 352-360. Oxford University Press
Aims Atrial fibrillation (AF) is a progressive disease, but identifying patients at risk for AF progression is challenging. We aimed to identify factors associated with AF progression. Methods and results Atrial fibrillation progression was assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fbaeba9e4460746c3859d7b5ef899e
https://doi.org/10.1093/europace/euz339
https://doi.org/10.1093/europace/euz339
Autor:
Jeremy, Lagrange, Bianca, Wagner, Markus, Nagler, Vincent, Ten Cate, Alejandro, Pallares Robles, Thomas, Koeck, Steffen, Rapp, Jürgen H, Prochaska, Henri M, Spronk, Philip, Wenzel, Wolfram, Ruf, Hugo, Ten Cate, Philipp S, Wild, Marina, Panova-Noeva
Publikováno v:
Journal of Clinical Medicine, 9(9):2892. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine, Vol 9, Iss 2892, p 2892 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2020, 9 (9), pp.2892. ⟨10.3390/jcm9092892⟩
Journal of Clinical Medicine, Vol 9, Iss 2892, p 2892 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2020, 9 (9), pp.2892. ⟨10.3390/jcm9092892⟩
Background. Anticoagulant therapy, the cornerstone treatment in acute venous thromboembolism (VTE), strongly impacts thrombin generation (TG). Until now, the appearance of the TG curve in platelet rich plasma (PRP) from patients with acute VTE has no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eca4b4849928af9b16f6a2ec9a2759
https://cris.maastrichtuniversity.nl/en/publications/d584801d-a1ea-47d1-af48-868069feb77d
https://cris.maastrichtuniversity.nl/en/publications/d584801d-a1ea-47d1-af48-868069feb77d
Autor:
Marijke C. Trappenburg, Muriel van Schilfgaarde, Marina Marchetti, Henri M. Spronk, Hugo ten Cate, Anja Leyte, Wim E. Terpstra, Anna Falanga
Publikováno v:
Haematologica, Vol 94, Iss 7 (2009)
Background Most cell types, including blood - and vascular cells, produce microparticles upon activation. Since cellular microparticles are known to be elevated in thromboembolic diseases, we hypothesized a role for microparticles in the pathogenesis
Externí odkaz:
https://doaj.org/article/2301ecab60bd4a1c94de005233763846
Autor:
Jelle J Posthuma, Jens J Posma, Goof Schep, Mart Bender, Rene van Oerle, Hugo ten Cate, Henri M Spronk
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Background: High performance athletes can develop symptomatic arterial flow restriction during exercise, caused by endofibrosis. The disease is an poorly understood condition, characterized by fibrosis of the external iliac artery. Pathophysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d9ccec6b9faa0d1530916c950b2beb
https://doi.org/10.1161/atvb.37.suppl_1.328
https://doi.org/10.1161/atvb.37.suppl_1.328