Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Henri Gruffat"'
Autor:
Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011176 (2023)
[This corrects the article DOI: 10.1371/journal.ppat.1008093.].
Externí odkaz:
https://doaj.org/article/eda1ced904054856aebe7c69698f4dc6
Autor:
Francesca Manara, Antonin Jay, Grace Akinyi Odongo, Fabrice Mure, Mohamed Ali Maroui, Audrey Diederichs, Cecilia Sirand, Cyrille Cuenin, Massimo Granai, Lucia Mundo, Hector Hernandez-Vargas, Stefano Lazzi, Rita Khoueiry, Henri Gruffat, Zdenko Herceg, Rosita Accardi
Publikováno v:
Cancers, Vol 14, Iss 5, p 1284 (2022)
Burkitt lymphoma (BL) is a malignant B cell neoplasm that accounts for almost half of pediatric cancers in sub-Saharan African countries. Although the BL endemic prevalence is attributable to the combination of Epstein–Barr virus (EBV) infection wi
Externí odkaz:
https://doaj.org/article/4c02977cad654ff2bd9c9b1078285aa0
Autor:
Hector Hernandez-Vargas, Henri Gruffat, Marie Pierre Cros, Audrey Diederichs, Cécilia Sirand, Romina C. Vargas-Ayala, Antonin Jay, Geoffroy Durand, Florence Le Calvez-Kelm, Zdenko Herceg, Evelyne Manet, Christopher P. Wild, Massimo Tommasino, Rosita Accardi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Epstein-Barr virus (EBV) was identified as the first human virus to be associated with a human malignancy, Burkitt’s lymphoma (BL), a pediatric cancer endemic in sub-Saharan Africa. The exact mechanism of how EBV contributes to the process
Externí odkaz:
https://doaj.org/article/cf771775f0f0480bba14d8ec7e78bb0a
Autor:
Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 15, Iss 10, p e1008093 (2019)
ISG20 is a broad spectrum antiviral protein thought to directly degrade viral RNA. However, this mechanism of inhibition remains controversial. Using the Vesicular Stomatitis Virus (VSV) as a model RNA virus, we show here that ISG20 interferes with v
Externí odkaz:
https://doaj.org/article/fd5eb53e1ce84c2d8b20cc67e6f77bbd
Autor:
Kevin Tartour, Xuan-Nhi Nguyen, Romain Appourchaux, Sonia Assil, Véronique Barateau, Louis-Marie Bloyet, Julien Burlaud Gaillard, Marie-Pierre Confort, Beatriz Escudero-Perez, Henri Gruffat, Saw See Hong, Marie Moroso, Olivier Reynard, Stéphanie Reynard, Elodie Decembre, Najate Ftaich, Axel Rossi, Nannan Wu, Frédérick Arnaud, Sylvain Baize, Marlène Dreux, Denis Gerlier, Glaucia Paranhos-Baccala, Viktor Volchkov, Philippe Roingeard, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006610 (2017)
IFITMs are broad antiviral factors that block incoming virions in endosomal vesicles, protecting target cells from infection. In the case of HIV-1, we and others reported the existence of an additional antiviral mechanism through which IFITMs lead to
Externí odkaz:
https://doaj.org/article/a1ae7ec7be9d4b84a06a17adedcfc46d
Publikováno v:
Cancers, Vol 10, Iss 4, p 109 (2018)
The presence of the Epstein-Barr virus (EBV)-encoded nuclear antigen-1 (EBNA1) protein in all EBV-carrying tumours constitutes a marker that distinguishes the virus-associated cancer cells from normal cells and thereby offers opportunities for target
Externí odkaz:
https://doaj.org/article/9c91a5ced6994e13b79f9a92a0056a8d
Autor:
Maha Siouda, Cecilia Frecha, Rosita Accardi, Jiping Yue, Cyrille Cuenin, Henri Gruffat, Evelyne Manet, Zdenko Herceg, Bakary S Sylla, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004125 (2014)
The DOK1 tumor suppressor gene encodes an adapter protein that acts as a negative regulator of several signaling pathways. We have previously reported that DOK1 expression is up-regulated upon cellular stress, via the transcription factor E2F1, and d
Externí odkaz:
https://doaj.org/article/e6e18cb857244a5ea9da090b3c3287f5
Autor:
Rosita Accardi, Ikbal Fathallah, Henri Gruffat, Giuseppe Mariggiò, Florence Le Calvez-Kelm, Catherine Voegele, Birke Bartosch, Hector Hernandez-Vargas, James McKay, Bakary S Sylla, Evelyne Manet, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003186 (2013)
Many studies have proved that oncogenic viruses develop redundant mechanisms to alter the functions of the tumor suppressor p53. Here we show that Epstein-Barr virus (EBV), via the oncoprotein LMP-1, induces the expression of ΔNp73α, a strong antag
Externí odkaz:
https://doaj.org/article/2daa063bc6114b1cb45f39acefab311a
Autor:
Guillermo A Orsi, Ahmed Algazeery, Régis E Meyer, Michèle Capri, Laure M Sapey-Triomphe, Béatrice Horard, Henri Gruffat, Pierre Couble, Ounissa Aït-Ahmed, Benjamin Loppin
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003285 (2013)
The differentiation of post-meiotic spermatids in animals is characterized by a unique reorganization of their nuclear architecture and chromatin composition. In many species, the formation of sperm nuclei involves the massive replacement of nucleoso
Externí odkaz:
https://doaj.org/article/2dfdc87fbaa04cc88a0133f988abb022
Autor:
Sarah J Dickerson, Yongna Xing, Amanda R Robinson, William T Seaman, Henri Gruffat, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 5, Iss 3, p e1000356 (2009)
The switch between latent and lytic Epstein-Barr virus (EBV) infection is mediated by the viral immediate-early (IE) protein, BZLF1 (Z). Z, a homologue of c-jun that binds to AP1-like motifs (ZREs), induces expression of the BRLF1 (R) and BRRF1 (Na)
Externí odkaz:
https://doaj.org/article/8f261fa6325e48f2a2f688a2e99484ae