Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Henri Doods"'
Autor:
Malarvizhi Gurusamy, Saeed Nasseri, Dileep Reddy Rampa, Huiying Feng, Dongwon Lee, Anton Pekcec, Henri Doods, Dongmei Wu
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-13 (2023)
Abstract Background Airway remodeling is an important pathological feature of chronic airway diseases, which leads to a progressive decline in lung function. The present study examined the anti-remodeling and anti- inflammatory effect of BIBF1000, a
Externí odkaz:
https://doaj.org/article/266238147ea6421c9ed6e0effd4f7cd5
Autor:
Dileep Reddy Rampa, Huiying Feng, Sivakumar Allur-Subramaniyan, Kwanseob Shim, Anton Pekcec, Dongwon Lee, Henri Doods, Dongmei Wu
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background and aims Kinin B1 receptors (B1Rs) are implicated in the pathogenesis of fibrosis. This study examined the anti-fibrotic effects of B1R blockade with BI 113823 in two established mouse models of hepatic fibrosis induced by intrape
Externí odkaz:
https://doaj.org/article/ed741575167b41e39ebe8f2cd2f06414
Autor:
Dileep Reddy Rampa, Priya Murugesan, Honglu Chao, Huiying Feng, Wenxin Dai, Dongwon Lee, Anton Pekcec, Henri Doods, Dongmei Wu
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background This study examined whether BI113823, a novel selective kinin B1 receptor antagonist can reverse established pulmonary arterial hypertension (PAH), prevent right heart failure and death, which is critical for clinical translation.
Externí odkaz:
https://doaj.org/article/6486253743b248c48dd7c38ef7667413
Autor:
Malarvizhi Gurusamy, Saeed Nasseri, Dileep Reddy Rampa, Huiying Feng, Dongwon Lee, Anton Pekcec, Henri Doods, Dongmei Wu
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background To examine the effects of BI 1029539 (GS-248), a novel selective human microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, in experimental models of acute lung injury (ALI) and sepsis in transgenic mice constitutively expre
Externí odkaz:
https://doaj.org/article/35632fa1b861488a9bc88054c6b87659
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51151 (2012)
The aim of the present study was to evaluate the cardiovascular effects of the novel bradykinin B1 receptor antagonist BI-113823 following myocardial infarction (MI) and to determine whether B1 receptor blockade alters the cardiovascular effects of a
Externí odkaz:
https://doaj.org/article/37639671be784702b60b78f4e1947186
Autor:
Marcus Schindler, Henri Doods
Publikováno v:
The Scientific World Journal, Vol 1, Pp 46-46 (2001)
Externí odkaz:
https://doaj.org/article/e38d5a83a5d046aa8e62e50d8389b107
Autor:
Anton Pekcec, Dongmei Wu, Wenxin Dai, Henri Doods, Dileep Reddy Rampa, Priya Murugesan, Dongwon Lee, Huiying Feng, Honglu Chao
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-16 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-16 (2021)
BackgroundThis study examined whether BI113823, a novel selective kinin B1 receptor antagonist can reverse established pulmonary arterial hypertension (PAH), prevent right heart failure and death, which is critical for clinical translation.MethodsLef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54d62d8c16890443f528cad3f29f918
http://europepmc.org/articles/PMC8557528
http://europepmc.org/articles/PMC8557528
Autor:
Dongmei Wu, Dileep Reddy Rampa, Anton Pekcec, Henri Doods, Saeed Nasseri, Huiying Feng, Dongwon Lee, Malarvizhi Gurusamy
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Background To examine the effects of BI 1029539 (GS-248), a novel selective human microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, in experimental models of acute lung injury (ALI) and sepsis in transgenic mice constitutively expressing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a3234e460e64b6dd083c0ee90d0b70
https://doi.org/10.1186/s12967-021-03016-9
https://doi.org/10.1186/s12967-021-03016-9
Publikováno v:
Behavioural Brain Research. 350:129-138
Background Burrowing is a rodent behavior validated as a robust and reproducible outcome measure to infer the global effect of pain in several inflammatory pain models. However, less is known about the effect of analgesics on burrowing in neuropathic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b36d5d2f7ac733f3a2e35c504c935e7
https://doi.org/10.1016/j.bbr.2018.04.049
https://doi.org/10.1016/j.bbr.2018.04.049
Autor:
Anton Pekcec, Henri Doods, Björn Bauer, Anika M.S. Hartz, Ken Ichi Hosoya, Emma L. B. Soldner, Shin-Ichi Akanuma, Richard J. Kryscio
Publikováno v:
FASEB J
The cause of antiseizure drug (ASD) resistance in epilepsy is poorly understood. Here, we focus on the transporter P-glycoprotein (P-gp) that is partly responsible for limited ASD brain uptake, which is thought to contribute to ASD resistance. We pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03733d002f20d774d17f5e9770926128
https://pubmed.ncbi.nlm.nih.gov/31638830
https://pubmed.ncbi.nlm.nih.gov/31638830