Výsledky vyhledávání - "Henri Baptiste"

Akademický článek

A combination of a cell penetrating peptide and a protein translation inhibitor kills metastatic breast cancer cells

Autor: Linda Rowland, Henri-Baptiste Marjault, Ola Karmi, DeAna Grant, Lauren J. Webb, Assaf Friedler, Rachel Nechushtai, Ron Elber, Ron Mittler

Publikováno v: Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)

Abstract Cell Penetrating Peptides (CPPs) are promising anticancer and antimicrobial drugs. We recently reported that a peptide derived from the human mitochondrial/ER membrane-anchored NEET protein, Nutrient Autophagy Factor 1 (NAF-1; NAF-144-67), s

Externí odkaz: https://doaj.org/article/b4d3c35acc764f168760d30991e8cfdd

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An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters

Autor: Henri-Baptiste Marjault, Ola Karmi, Ke Zuo, Dorit Michaeli, Yael Eisenberg-Domovich, Giulia Rossetti, Benoit de Chassey, Jacky Vonderscher, Ioav Cabantchik, Paolo Carloni, Ron Mittler, Oded Livnah, Eric Meldrum, Rachel Nechushtai

Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)

Marjault et al. report two crystal structures of a drug molecule bound to NEET proteins mNT and NAF-1 and the effects of this molecule on diabetic mice, suggesting an approach for reducing mitochondrial iron and ROS levels in diabetic patients.

Externí odkaz: https://doaj.org/article/5fdc9f8e63f74c36ac4f3fdb8fd0831a

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A house is not a home: housing disadvantage, homelessness, and modern slavery

Autor: Henri Baptiste, Charlotte Grey, Nicola Wright, Carla Reeson, Steve Iafrati, Nick Clare

Publikováno v: Journal of the British Academy. 11:83-93

This commentary focuses on the underexplored links between housing disadvantage, homelessness, and modern slavery. Despite significant anecdotal evidence, there is a pressing need for proper theorisation of the connections between housing situation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d62cd3d61aeda2b46371218bab6e8132
https://doi.org/10.5871/jba/011.083

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Akademický článek

An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.

Autor: Marjault, Henri-Baptiste^1,2 (AUTHOR), Karmi, Ola^1,3 (AUTHOR), Zuo, Ke^1,2 (AUTHOR), Michaeli, Dorit¹ (AUTHOR), Eisenberg-Domovich, Yael¹ (AUTHOR), Rossetti, Giulia^2,4,5 (AUTHOR), de Chassey, Benoit⁶ (AUTHOR), Vonderscher, Jacky⁶ (AUTHOR), Cabantchik, Ioav¹ (AUTHOR), Carloni, Paolo^2,4,5,7 (AUTHOR), Mittler, Ron³ (AUTHOR), Livnah, Oded¹ (AUTHOR), Meldrum, Eric⁶ (AUTHOR), Nechushtai, Rachel¹ (AUTHOR) Rachel@mail.huji.ac.il

Publikováno v: Communications Biology. 5/10/2022, Vol. 5 Issue 1, p1-9. 9p.

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CISD3 is required for Complex I function, mitochondrial integrity, and skeletal muscle maintenance

Autor: Marjault, Henri-Baptiste, Karmi, Ola, Rowland, Linda, Nguyen, Thi Thao, Grant, DeAna, Manrique-Acevedo, Camila, Nechushtai, Rachel, Mittler, Ron

Publikováno v: bioRxiv

Mitochondria play a central role in muscle metabolism and function. In skeletal muscles, a unique family of iron-sulfur proteins, termed CISD proteins, support mitochondrial function. The abundance of these proteins declines with aging leading to mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::748132cab7b371a72e5dd4a21635379c
https://europepmc.org/articles/PMC10312576/

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A Combined Drug Treatment That Reduces Mitochondrial Iron and Reactive Oxygen Levels Recovers Insulin Secretion in NAF-1-Deficient Pancreatic Cells

Autor: Ola Karmi, Yang-Sung Sohn, Henri-Baptiste Marjault, Tal Israeli, Gil Leibowitz, Konstantinos Ioannidis, Yaakov Nahmias, Ron Mittler, Ioav Z. Cabantchik, Rachel Nechushtai

Publikováno v: Antioxidants, Vol 10, Iss 8, p 1160 (2021)

Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen speci

Externí odkaz: https://doaj.org/article/445d18587fbe4b629ebd01f35f244779

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The two redox states of the human NEET proteins' [2Fe–2S] clusters.

Autor: Zuo, Ke^1,2 (AUTHOR), Marjault, Henri-Baptiste^1,2 (AUTHOR), Bren, Kara L.³ (AUTHOR), Rossetti, Giulia^4,5,6 (AUTHOR), Nechushtai, Rachel¹ (AUTHOR) rachel@mail.huji.ac.il, Carloni, Paolo^2,4,7 (AUTHOR) p.carloni@fz-juelich.de

Publikováno v: Journal of Biological Inorganic Chemistry (JBIC). Oct2021, Vol. 26 Issue 7, p763-774. 12p.

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