Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Henri, Martens"'
Autor:
Aymen Halouani, Habib Jmii, Gwennaëlle Bodart, Hélène Michaux, Chantal Renard, Henri Martens, Mahjoub Aouni, Didier Hober, Vincent Geenen, Hela Jaïdane
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The thymus is the main organ of the lymphatic system, in which T cells undergo a rigorous selection to ensure that their receptors (TCRs) will be functional and will not react against the self. Genes encoding for TCR chains are fragmented and must be
Externí odkaz:
https://doaj.org/article/454265833b714b7f833cb221d4f79f86
Autor:
Florence Potier, Jean-Marie Degryse, Benoit Bihin, Florence Debacq-Chainiaux, Chantal Charlet-Renard, Henri Martens, Marie de Saint-Hubert
Publikováno v:
BMC Geriatrics, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Among older couples, spouses are first in line to provide care, and they are key elements in the home support of dependent older persons. In this context, ensuring the health of these older spousal caregivers should be an importan
Externí odkaz:
https://doaj.org/article/5c14ad88391f44ae8a01b0cf46f38f5e
Autor:
Aymen Halouani, Hélène Michaux, Habib Jmii, Charlotte Trussart, Ahlem Chahbi, Henri Martens, Chantal Renard, Mahjoub Aouni, Didier Hober, Vincent Geenen, Hela Jaïdane
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1537 (2021)
Thymus plays a fundamental role in central tolerance establishment, especially during fetal life, through the generation of self-tolerant T cells. This process consists in T cells education by presenting them tissue-restricted autoantigens promiscuou
Externí odkaz:
https://doaj.org/article/bc0164fd0c0c4a26840365a8c52da641
Autor:
Abdulaziz Alhazmi, Magloire Pandoua Nekoua, Hélène Michaux, Famara Sane, Aymen Halouani, Ilka Engelmann, Enagnon Kazali Alidjinou, Henri Martens, Hela Jaidane, Vincent Geenen, Didier Hober
Publikováno v:
Microorganisms, Vol 9, Iss 6, p 1177 (2021)
The thymus gland is a primary lymphoid organ for T-cell development. Various viral infections can result in disturbance of thymic functions. Medullary thymic epithelial cells (mTECs) are important for the negative selection of self-reactive T-cells t
Externí odkaz:
https://doaj.org/article/96260ffeedd64a1daf87bc6bf2a83c18
Autor:
Hélène Michaux, Aymen Halouani, Charlotte Trussart, Chantal Renard, Hela Jaïdane, Henri Martens, Vincent Geenen, Didier Hober
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 402 (2021)
Coxsackievirus B4 (CV-B4) can infect human and murine thymic epithelial cells (TECs). In a murine TEC cell line, CV-B4 can downregulate the transcription of the insulin-like growth factor 2 (Igf2) gene coding for the self-peptide of the insulin famil
Externí odkaz:
https://doaj.org/article/553fb9929ec84bacbaaa84dd3982273c
Autor:
Khalil Farhat, Gwennaëlle Bodart, Chantal Charlet-Renard, Christophe J. Desmet, Michel Moutschen, Yves Beguin, Frédéric Baron, Pierrette Melin, Pascale Quatresooz, Anne-Simone Parent, Daniel Desmecht, Jean-Claude Sirard, Roberto Salvatori, Henri Martens, Vincent G. Geenen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The precise impact of the somatotrope axis upon the immune system is still highly debated. We have previously shown that mice with generalized ablation of growth hormone (GH) releasing hormone (GHRH) gene (Ghrh−/−) have normal thymus and T-cell d
Externí odkaz:
https://doaj.org/article/22a608eee038493ab976b36623155722
Autor:
Gwennaelle Bodart, Khalil Farhat, Chantal Renard-Charlet, Guillaume Becker, Alain Plenevaux, Roberto Salvatori, Vincent Geenen, Henri Martens
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
A debate is still open about the precise control exerted by the somatotrope GH-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor 1 axis on the immune system. The objective of this study was to directly address this question thro
Externí odkaz:
https://doaj.org/article/178947b112cb44108e865762f0488695
Autor:
Adrien De Voeght, Henri Martens, Chantal Renard, Dolores Vaira, Mathieu Debruche, Julie Simonet, Vincent Geenen, Michel Moutschen, Gilles Darcis
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185761 (2017)
Microbial translocation is now viewed as a central event in the pathogenesis of chronic inflammation during HIV infection. Thymic function failure is another crucial factor involved in HIV disease progression. The goal of this study was to explore th
Externí odkaz:
https://doaj.org/article/021bdb5e68804fc6abe8f0e5766170b6
Autor:
Vincent Geenen, Hela Jaïdane, Henri Martens, Caroline Collée, Aymen Halouani, Chantal Renard, Philippe Ledent, Charlotte Trussart, Hélène Michaux, Marc Daukandt
Publikováno v:
Annals of the New York Academy of Sciences
Confirming Burnet's early hypothesis, elimination of self‐reactive T cells in the thymus was demonstrated in the late 1980s, and an important question immediately arose about the nature of the self‐peptides expressed in the thymus. Many genes enc
Autor:
Habib Jmii, Chantal Renard, Vincent Geenen, Henri Martens, Didier Hober, Gwennaëlle Bodart, Hélène Michaux, Hela Jaïdane, Aymen Halouani, Mahjoub Aouni
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The thymus is the main organ of the lymphatic system, in which T cells undergo a rigorous selection to ensure that their receptors (TCRs) will be functional and will not react against the self. Genes encoding for TCR chains are fragmented and must be