Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates.

Autor: García-Huerta P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile., Troncoso-Escudero P; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile., Wu D; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Thiruvalluvan A; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Cisternas-Olmedo M; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile., Henríquez DR; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile., Plate L; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Chana-Cuevas P; Faculty of Medical Sciences, University of Santiago de Chile, Santiago, Chile., Saquel C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile., Thielen P; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA, 02115, USA., Longo KA; Proteostasis Therapeutics, Cambridge, MA, USA., Geddes BJ; Proteostasis Therapeutics, Cambridge, MA, USA., Lederkremer GZ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel., Sharma N; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel., Shenkman M; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.; George Wise Faculty of Life Sciences, School of Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, Israel., Naphade S; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Sardi SP; Rare and Neurological Diseases Therapeutic Area, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA., Spichiger C; Faculty of Sciences, Institute of Biochemistry and Microbiology, University Austral of Chile, Valdivia, Chile., Richter HG; Faculty of Medicine, Institute of Anatomy, Histology and Pathology, University Austral of Chile, Valdivia, Chile., Court FA; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Tshilenge KT; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Ellerby LM; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Wiseman RL; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA., Gonzalez-Billault C; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Department of Cell Biology, Faculty of Sciences, University of Chile, Santiago, Chile.; Buck Institute for Research on Aging, Novato, CA, 94945, USA., Bergink S; Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Vidal RL; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. rene.vidal@umayor.cl.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. rene.vidal@umayor.cl.; Center for Integrative Biology, Faculty of Sciences, University Mayor, Santiago, Chile. rene.vidal@umayor.cl., Hetz C; Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile. chetz@med.uchile.cl.; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. chetz@med.uchile.cl.; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Sector B, Second Floor, Faculty of Medicine, University of Chile, Independencia 1027, P.O. Box 70086, Santiago, Chile. chetz@med.uchile.cl.; Buck Institute for Research on Aging, Novato, CA, 94945, USA. chetz@med.uchile.cl.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2020 Nov; Vol. 140 (5), pp. 737-764. Date of Electronic Publication: 2020 Jul 08.

Corrigendum: Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology.

Autor: Bodaleo FJ, Montenegro-Venegas C, Henríquez DR, Court FA, Gonzalez-Billault C

Publikováno v: Scientific reports [Sci Rep] 2016 Sep 02; Vol. 6, pp. 32275. Date of Electronic Publication: 2016 Sep 02.

Rab35 Functions in Axon Elongation Are Regulated by P53-Related Protein Kinase in a Mechanism That Involves Rab35 Protein Degradation and the Microtubule-Associated Protein 1B.

Autor: Villarroel-Campos D; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile., Henríquez DR; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile., Bodaleo FJ; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile., Oguchi ME; Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Tohoku University, Sendai 980-8577, Japan., Bronfman FC; MINREB and CARE Center, Department of Physiology, Pontificia Universidad Católica de Chile, Santiago 8331150, Chile, and., Fukuda M; Laboratory of Membrane Trafficking Mechanisms, Department of Developmental Biology and Neurosciences, Tohoku University, Sendai 980-8577, Japan., Gonzalez-Billault C; Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile, Center for Geroscience, Brain Health and Metabolism, Santiago, Chile, The Buck Institute for Research on Aging, Novato, California 94945, chrgonza@uchile.cl.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2016 Jul 06; Vol. 36 (27), pp. 7298-313.

CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation.

Autor: Gandini MA; Department of Cell Biology, Center for Research and Advanced Studies of the National Polytechnic Institute, (Cinvestav-IPN), Avenida IPN 2508, Colonia Zacatenco, Mexico DF, 07360, Mexico., Henríquez DR, Grimaldo L, Sandoval A, Altier C, Zamponi GW, Felix R, González-Billault C

Publikováno v: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2014 Nov; Vol. 466 (11), pp. 2113-26. Date of Electronic Publication: 2014 Feb 26.

Geobacillus stearothermophilus LV cadA gene mediates resistance to cadmium, lead and zinc in zntA mutants of Salmonella entérica serovar Typhimurium.

Autor: Pérez JM; Laboratorio de Microbiología Molecular, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile. cvasquez@usach.cl, Pradeñas GA, Navarro CA, Henríquez DR, Pichuantes SE, Vásquez CC

Publikováno v: Biological research [Biol Res] 2006; Vol. 39 (4), pp. 661-8. Date of Electronic Publication: 2007 Jul 20.