Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Henning T. Langer"'
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract The tumor suppressor p53 is thought to play a key role in the maintenance of cell size and homeostasis, but relatively little is known about its role in skeletal muscle. Based on its ability to suppress cell growth, we hypothesized that inhi
Externí odkaz:
https://doaj.org/article/ef6240e16b4e4e5cb6853dd2fc6ac799
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The molecular responses to acute resistance exercise are well characterized. However, how cellular signals change over time to modulate chronic adaptations to more prolonged exercise training is less well understood. We investigated anabolic
Externí odkaz:
https://doaj.org/article/2fd3abdcef4244e0a41224542d52f9a4
Autor:
Henning T. Langer, Agata A. Mossakowski, Brandon J. Willis, Kristin N. Grimsrud, Joshua A. Wood, Kevin C.K. Lloyd, Hermann Zbinden‐Foncea, Keith Baar
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1364-1376 (2020)
Abstract Background Desminopathy is a clinically heterogeneous muscle disease caused by over 60 different mutations in desmin. The most common mutation with a clinical phenotype in humans is an exchange of arginine to proline at position 350 of desmi
Externí odkaz:
https://doaj.org/article/e8ce417af22b4db2ac69360a6fbaccd9
Publikováno v:
Cell research. 32(12)
Publikováno v:
Physiological Reports, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract The mechanisms accounting for the loss of muscle function with obesity and type 2 diabetes are likely the result of a combination of neural and muscular factors. One muscular factor that is important, yet has received little attention, is th
Externí odkaz:
https://doaj.org/article/e6276e6739084c719e6b97680bee40a0
Publikováno v:
Cannabis and Cannabinoid Research. 7:628-636
Background: Cannabidiol (CBD) is becoming increasingly popular for the treatment of clinical conditions including as an aid for muscle recovery. Previous work demonstrated that CBD exhibited mild effects on skeletal muscle, with a tendency to increas
Autor:
Henning T. Langer, Joan M. G. Senden, Annemie P. Gijsen, Stefan Kempa, Luc J. C. van Loon, Simone Spuler
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Muscle loss is a severe complication of many medical conditions such as cancer, cardiac failure, muscular dystrophies, and nerve damage. The contribution of myofibrillar protein synthesis (MPS) to the loss of muscle mass after nerve damage is not cle
Externí odkaz:
https://doaj.org/article/4084ad94a93d49869532c01e8965ffa5
Autor:
Blaine A. Christiansen, Hailey C. Cunningham, Suraj Pathak, Keith Baar, Manali P. Paralkar, Armaun J. Emami, Benjamin Osipov, Henning T. Langer, Priscilla M. Tjandra
Publikováno v:
J Orthop Res
Fracture induces systemic bone loss in mice and humans, and a first (index) fracture increases the risk of future fracture at any skeletal site more in men than women. The etiology of this sex difference is unknown, but fracture may induces a greater
Muscle mass and strength are predictors of longevity. We have previously identified a series of molecular brakes that slow muscle growth in response to stress. One potential stress that we hypothesized would limit muscle growth is caloric stress thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62d816343e51bf698bf42b9d050c06e
https://doi.org/10.1101/2022.06.27.497838
https://doi.org/10.1101/2022.06.27.497838
Autor:
Kristin N Grimsrud, Henning T. Langer, Kevin C K Lloyd, Agata A. Mossakowski, Hermann Zbinden-Foncea, Joshua A. Wood, Keith Baar, Brandon J. Willis
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1364-1376 (2020)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
Author(s): Langer, Henning T; Mossakowski, Agata A; Willis, Brandon J; Grimsrud, Kristin N; Wood, Joshua A; Lloyd, Kevin CK; Zbinden-Foncea, Hermann; Baar, Keith | Abstract: BackgroundDesminopathy is a clinically heterogeneous muscle disease caused b