Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Henning Fröhlich"'
Autor:
Mai Iwasaki, Arthur Lefevre, Ferdinand Althammer, Etienne Clauss Creusot, Olga Łąpieś, Hugues Petitjean, Louis Hilfiger, Damien Kerspern, Meggane Melchior, Stephanie Küppers, Quirin Krabichler, Ryan Patwell, Alan Kania, Tim Gruber, Matthew K. Kirchner, Moritz Wimmer, Henning Fröhlich, Laura Dötsch, Jonas Schimmer, Sabine C. Herpertz, Beate Ditzen, Christian P. Schaaf, Kai Schönig, Dusan Bartsch, Anna Gugula, Aleksandra Trenk, Anna Blasiak, Javier E. Stern, Pascal Darbon, Valery Grinevich, Alexandre Charlet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally rele
Externí odkaz:
https://doaj.org/article/85fa7e14fa3741ae8af552981e58801d
Publikováno v:
Genes, Vol 13, Iss 1, p 127 (2022)
Reduced cognitive flexibility, characterized by restricted interests and repetitive behavior, is associated with atypical memory performance in autism spectrum disorder (ASD), suggesting hippocampal dysfunction. FOXP1 syndrome is a neurodevelopmental
Externí odkaz:
https://doaj.org/article/8e9e2555d63648b48f5da7f6d6210a7b
Autor:
Simone Berkel, Ahmed Eltokhi, Henning Fröhlich, Diana Porras-Gonzalez, Rafiullah Rafiullah, Rolf Sprengel, Gudrun A. Rappold
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Autism spectrum disorders (ASD) have a higher prevalence in male individuals compared to females, with a ratio of affected boys compared to girls of 4:1 for ASD and 11:1 for Asperger syndrome. Mutations in the SHANK genes (comprising SHANK1, SHANK2 a
Externí odkaz:
https://doaj.org/article/d53c594379bb49499865ae445c3616f1
Autor:
Xue Li, Jian Xiao, Henning Fröhlich, Xiaomeng Tu, Lianlian Li, Yue Xu, Huateng Cao, Jia Qu, Gudrun A Rappold, Jie-Guang Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127671 (2015)
FOXP1 is a member of FOXP subfamily transcription factors. Mutations in FOXP1 gene have been found in various development-related cognitive disorders. However, little is known about the etiology of these symptoms, and specifically the function of FOX
Externí odkaz:
https://doaj.org/article/7e0a091b07714da68f3ff8af3dd94f4c
Autor:
Ferdinand Althammer, Moritz Claudius Wimmer, Quirin Krabichler, Stephanie Küppers, Jonas Schimmer, Henning Fröhlich, Laura Dötsch, Tim Gruber, Selina Wunsch, Tim Schubert, Matthew K. Kirchner, Javier E. Stern, Alexandre Charlet, Valery Grinevich, Christian P. Schaaf
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 34(12)
Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by hyperphagia, obesity, developmental delay and intellectual disability. Studies suggest dysfunctional signaling of the neuropeptide oxytocin as one of the key mechanisms in
Autor:
null Ferdinand Althammer, null Moritz Claudius Wimmer, null Quirin Krabichler, null Stephanie Küppers, null Jonas Schimmer, null Henning Fröhlich, null Laura Dötsch, null Tim Gruber, null Selina Wunsch, null Tim Schubert, null Matthew K. Kirchner, null Javier E. Stern, null Alexandre Charlet, null Valery Grinevich, null Christian P. Schaaf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b35dc5957d10c26f6bdf5271dd43af
https://doi.org/10.1111/jne.13217/v3/response1
https://doi.org/10.1111/jne.13217/v3/response1
Autor:
Jing Wang, Henning Fröhlich, Felipe Bodaleo Torres, Rangel Leal Silva, Gernot Poschet, Amit Agarwal, Gudrun A. Rappold
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance FOXP1 haploinsufficiency underlies cognitive and motor impairments in individuals with FOXP1 syndrome. Here, we show that mice lacking one Foxp1 copy exhibit similar behavioral deficits, which may be caused by striatal dysfunction. Indee
Gastrointestinal dysfunction in autism displayed by altered motility and achalasia in Foxp1 +/− mice
Autor:
Manuel Stuhlinger, E Zizer, Beate Niesler, Dieter Groneberg, Henning Fröhlich, Gudrun A. Rappold, Marie Luise Kollmeyer, Amelie Reigl, Valerie Catherine Linz, Andreas Friebe
Publikováno v:
Proceedings of the National Academy of Sciences. 116:22237-22245
Gastrointestinal dysfunctions in individuals with autism spectrum disorder are poorly understood, although they are common among this group of patients. FOXP1 haploinsufficiency is characterized by autistic behavior, language impairment, and intellec
Autor:
Henning, Fröhlich, Marie Luise, Kollmeyer, Valerie Catherine, Linz, Manuel, Stuhlinger, Dieter, Groneberg, Amelie, Reigl, Eugen, Zizer, Andreas, Friebe, Beate, Niesler, Gudrun, Rappold
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(44)
Gastrointestinal dysfunctions in individuals with autism spectrum disorder are poorly understood, although they are common among this group of patients. FOXP1 haploinsufficiency is characterized by autistic behavior, language impairment, and intellec
Publikováno v:
Human Molecular Genetics. 26:1511-1521
Autism and speech and language deficits are predominantly found in boys, however the causative mechanisms for this sex bias are unknown. Human FOXP1 is associated with autism, intellectual disability and speech and language deficits. Its closely rela