Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hennie M. Hodemaekers"'
Autor:
Wim H. De Jong, Danyel Jennen, Peter H. J. Keizers, Hennie M. Hodemaekers, Jolanda P. Vermeulen, Frank Bakker, Paul Schwillens, Marcel van Herwijnen, Marlon Jetten, Jos C. S. Kleinjans, Robert E. Geertsma, Rob J. Vandebriel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7275 (2022)
Resorbable tissue fillers for aesthetic purposes can induce severe complications including product migration, late swelling, and inflammatory reactions. The relation between product characteristics and adverse effects is not well understood. We hypot
Externí odkaz:
https://doaj.org/article/a4e1529c0a964aff80735291fc951721
Autor:
Liana Bastos Sales, Joantine C. J. van Esterik, Hennie M. Hodemaekers, Marja H. Lamoree, Timo Hamers, Leo T. M. van der Ven, Juliette Legler
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Background: Developmental exposure to di (2-ethylhexyl) phthalate (DEHP) has been implicated in the onset of metabolic syndrome later in life. Alterations in neurobehavior and immune functions are also affected by phthalate exposure and may be linked
Externí odkaz:
https://doaj.org/article/444aca702ebd4be9afb555ba037ef9db
Autor:
Sander Ruiter, Josefine Sippel, Manon C. Bouwmeester, Tobias Lommelaars, Piet Beekhof, Hennie M. Hodemaekers, Frank Bakker, Evert-Jan van den Brandhof, Jeroen L. A. Pennings, Leo T. M. van der Ven
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 11, p 1830 (2016)
Non-communicable diseases (NCDs) are a major cause of premature mortality. Recent studies show that predispositions for NCDs may arise from early-life exposure to low concentrations of environmental contaminants. This developmental origins of health
Externí odkaz:
https://doaj.org/article/3d07e28e807946ea8d8e4832c35eaa18
Autor:
Wim H. De Jong, Danyel Jennen, Peter H. J. Keizers, Hennie M. Hodemaekers, Jolanda P. Vermeulen, Frank Bakker, Paul Schwillens, Marcel van Herwijnen, Marlon Jetten, Jos C. S. Kleinjans, Robert E. Geertsma, Rob J. Vandebriel
Publikováno v:
International journal of molecular sciences, 23(13):7275. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7275
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7275
Resorbable tissue fillers for aesthetic purposes can induce severe complications including product migration, late swelling, and inflammatory reactions. The relation between product characteristics and adverse effects is not well understood. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d0a7ab31dd1704f69f249822a95544
http://hdl.handle.net/10029/626514
http://hdl.handle.net/10029/626514
Autor:
Leo T.M. Van Der Ven, Paul Van Ommeren, Edwin P. Zwart, Eric R. Gremmer, Hennie M. Hodemaekers, Harm J. Heusinkveld, Jacob D. van Klaveren, Emiel Rorije
Publikováno v:
Environmental health perspectives. 130(4)
Humans are exposed to combinations of chemicals. In cumulative risk assessment (CRA), regulatory bodies such as the European Food Safety Authority consider dose addition as a default and sufficiently conservative approach. The principle of dose addit
Autor:
Victoria C. de Leeuw, Conny T.M. van Oostrom, Paul F.K. Wackers, Jeroen L.A. Pennings, Hennie M. Hodemaekers, Aldert H. Piersma, Ellen V.S. Hessel
Publikováno v:
Chemosphere
There is an increased awareness that the use of animals for compound-induced developmental neurotoxicity (DNT) testing has limitations. Animal-free innovations, especially the ones based on human stem cell-based models are pivotal in studying DNT sin
Autor:
Fatima den Ouden, Willem G. Schoonen, Emiel Rorije, Joop de Knecht, Edwin P. Zwart, Hennie M. Hodemaekers, Leo T.M. van der Ven, Renate M. Groot, Harm J. Heusinkveld
The zebrafish embryo toxicity test (ZFET) is a simple medium-throughput test to inform about (sub)acute lethal effects in embryos. Enhanced analysis through morphological and teratological scoring, and through gene expression analysis, detects develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cc6788abb3fe6d8eeabac5f930497a
http://hdl.handle.net/10029/624957
http://hdl.handle.net/10029/624957
Autor:
Celine Vanhee, Peter H. J. Keizers, Daan G.W. Lensen, Wim H. de Jong, Eef M.W. van den Elzen, Hennie M. Hodemaekers, Paul Schwillens, Bastiaan J. Venhuis
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 159:173-178
Facial treatments with dermal fillers for medical or esthetic purposes occasionally give rise to adverse effects, ranging from temporary effects such as reddening of the skin, to long term effects such as hardening of tissue. There appears to be a re
Autor:
Conny T. M. van Oostrom, Paul F.K. Wackers, Ellen V.S. Hessel, Hennie M. Hodemaekers, Jeroen L. A. Pennings, Aldert H. Piersma, Victoria C. de Leeuw
Publikováno v:
Neurotoxicology. 76
There is a need for in vitro tests for the evaluation of chemicals and pharmaceuticals that may cause developmental neurotoxicity (DNT) in humans. The neural embryonic stem cell test (ESTn) is such an in vitro test that mimics early neural differenti
Autor:
Teun Guichelaar, Sylvia S. N. Reemers, Jeroen L. A. Pennings, Riny Janssen, Rob Mariman, Hennie M. Hodemaekers
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Aging poses an increased risk of severe infection by respiratory syncytial virus (RSV). The many different biological pathways comprising the response to infection in lungs that are influenced by aging are complex and remain to be defined more thorou