Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hennie M J, Roelofs"'
Autor:
Yannick Wouters, Daisy Dalloyaux, Anke Christenhusz, Hennie M. J. Roelofs, Heiman F. Wertheim, Chantal P. Bleeker‐Rovers, René H. teMorsche, Geert J. A. Wanten
Publikováno v:
Microbial Biotechnology, Vol 13, Iss 3, Pp 657-668 (2020)
Summary The droplet digital polymerase chain reaction (ddPCR) is a novel molecular technique that allows rapid quantification of rare target DNA sequences. Aim of this study was to explore the feasibility of the ddPCR technique to detect pathogen DNA
Externí odkaz:
https://doaj.org/article/4a525bcc75304f8887d89602749263ef
Autor:
Mark M T J Broekman, Hennie M J Roelofs, Frank Hoentjen, Renske Wiegertjes, Nicole Stoel, Leo A Joosten, Dirk J de Jong, Geert J A Wanten
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133932 (2015)
Crohn's disease (CD) is a chronic inflammatory disease in which cytokines play a pivotal role in the induction and maintenance of inflammation. Innate cytokine production is genetically determined and varies largely between individuals; this might im
Externí odkaz:
https://doaj.org/article/6b1ddfebdae1475bad81d3c780829332
Autor:
Jennie Ong, Jody Salomon, Rene H M te Morsche, Hennie M J Roelofs, Ben J M Witteman, Polat Dura, Martin Lacko, Wilbert H M Peters
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90916 (2014)
INTRODUCTION: Numerous factors influence the development of gastrointestinal (GI) cancer. The insulin-like growth factor (IGF) axis plays a role in embryonic and postnatal growth and tissue repair. Elevated levels of IGFs, low levels of IGF binding p
Externí odkaz:
https://doaj.org/article/b75f5c8299594f309e4e72230e2f05b9
Autor:
Martin, Lacko, Adri C, Voogd, Rens C E, van de Goor, Hennie M J, Roelofs, Rene H M, Te Morsche, Nicole D, Bouvy, Wilbert H M, Peters, Johannes J, Manni
Publikováno v:
Headneck. 38
Warthin's tumors of the parotid gland are associated with smoking, whereas pleomorphic adenomas are not. Genetic polymorphisms in biotransformation enzymes, involved in detoxification of toxins and carcinogens in cigarette smoke, might modify the cor
Autor:
Polat, Dura, Elke M, van Veen, Jody, Salomon, Rene H M, te Morsche, Hennie M J, Roelofs, Jon O, Kristinsson, Theo, Wobbes, Ben J M, Witteman, Adriaan C I T L, Tan, Joost P H, Drenth, Wilbert H M, Peters
Publikováno v:
International journal of cancer. 133(7)
Barrett's esophagus, with gastroesophageal reflux disease and obesity as risk factors, predisposes to esophageal adenocarcinoma (EAC). Recently a British genome wide association study identified two Barrett's esophagus susceptibility loci mapping wit
Autor:
Marloes A A, Schepens, Carolien, Vink, Arjan J, Schonewille, Hennie M J, Roelofs, Robert-Jan, Brummer, Roelof, van der Meer, Ingeborg M J, Bovee-Oudenhoven
Publikováno v:
Inflammatory bowel diseases. 17(10)
Oxidative stress is presumed to play an important role in inflammatory bowel disease (IBD). Accordingly, antioxidant supplementation might be protective. Dietary calcium inhibited colitis development in HLA-B27 transgenic rats, an animal model mimick
Autor:
Wilbert H M, Peters, Rene H M, te Morsche, Hennie M J, Roelofs, Elisabeth M H, Mathus-Vliegen, Marloes, Berkhout, Fokko M, Nagengast
Publikováno v:
Oncology research. 17(8)
Cyclooxygenase-2 (COX-2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of biologic processes such as inflammation, cell proliferation, and angiogenesis. COX-2 has been found overexpressed in (pre)mali
Autor:
Elise M J, Van Der Logt, Cynthia H J M, Janssen, Zairah, Van Hooijdonk, Hennie M J, Roelofs, Theo, Wobbes, Fokko M, Nagengast, Wilbert H M, Peters
Publikováno v:
Anticancer research. 25(2B)
Impaired metabolism of ingested toxic or carcinogenic compounds is a postulated mechanism underlying colorectal cancer (CRC). Furthermore, it is suggested that reactive oxygen species (ROS) may play a role in human cancer development. Polymorphic var
Autor:
Elise M J, Van der Logt, Hennie M J, Roelofs, Esther M M, van Lieshout, Fokko M, Nagengast, Wilbert H M, Peters
Publikováno v:
Anticancer research. 24(2B)
Dietary compounds or nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce cancer rates. Elevation of phase II detoxification enzymes might be one of the mechanisms leading to cancer prevention. We investigated the effects of dietary anticarcinoge