Zobrazeno 1 - 10
of 2 145
pro vyhledávání: '"Henne P"'
Autor:
Meiyue Wang, Heinrich Flaswinkel, Abhinav Joshi, Matteo Napoli, Sergi Masgrau-Alsina, Julia M. Kamper, Antonia Henne, Alexander Heinz, Marleen Berouti, Niklas A. Schmacke, Karsten Hiller, Elisabeth Kremmer, Benedikt Wefers, Wolfgang Wurst, Markus Sperandio, Jürgen Ruland, Thomas Fröhlich, Veit Hornung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Innate immune responses are linked to key metabolic pathways, yet the proximal signaling events that connect these systems remain poorly understood. Here we show that phosphofructokinase 1, liver type (PFKL), a rate-limiting enzyme of glycol
Externí odkaz:
https://doaj.org/article/1927e1207bb440388975d052a11a059b
Pan-Arctic methanesulfonic acid aerosol: source regions, atmospheric drivers, and future projections
Autor:
Jakob Boyd Pernov, Eliza Harris, Michele Volpi, Tamara Baumgartner, Benjamin Hohermuth, Stephan Henne, William H. Aeberhard, Silvia Becagli, Patricia K. Quinn, Rita Traversi, Lucia M. Upchurch, Julia Schmale
Publikováno v:
npj Climate and Atmospheric Science, Vol 7, Iss 1, Pp 1-18 (2024)
Abstract Natural aerosols are an important, yet understudied, part of the Arctic climate system. Natural marine biogenic aerosol components (e.g., methanesulfonic acid, MSA) are becoming increasingly important due to changing environmental conditions
Externí odkaz:
https://doaj.org/article/118ed917fcec44dfa8636a9739890ebf
Autor:
Ernie Yulyaningsih, Jung H Suh, Melania Fanok, Roni Chau, Hilda Solanoy, Ryan Takahashi, Anna I Bakardjiev, Isabel Becerra, N Butch Benitez, Chi-Lu Chiu, Sonnet S Davis, William E Dowdle, Timothy Earr, Anthony A Estrada, Audrey Gill, Connie Ha, Patrick CG Haddick, Kirk R Henne, Martin Larhammar, Amy W-S Leung, Romeo Maciuca, Bahram Memarzadeh, Hoang N Nguyen, Alicia A Nugent, Maksim Osipov, Yingqing Ran, Kevin Rebadulla, Elysia Roche, Thomas Sandmann, Jing Wang, Joseph W Lewcock, Kimberly Scearce-Levie, Lesley A Kane, Pascal E Sanchez
Publikováno v:
eLife, Vol 12 (2024)
The integrated stress response (ISR) is a conserved pathway in eukaryotic cells that is activated in response to multiple sources of cellular stress. Although acute activation of this pathway restores cellular homeostasis, intense or prolonged ISR ac
Externí odkaz:
https://doaj.org/article/6521500dd1424027bebffc6920eba56b
Autor:
Annabell Wolff, Paula Krone, Johanna Maennicke, Julia Henne, Sonja Oehmcke-Hecht, Caterina Redwanz, Wendy Bergmann-Ewert, Christian Junghanss, Larissa Henze, Claudia Maletzki
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102053- (2024)
Background: The CDK4/6 inhibitor abemaciclib is an FDA-approved agent and induces T-cell-mediated immunity. Previously, we confirmed the therapeutic potential of abemaciclib on mismatch repair-deficient (dMMR) tumors in mice. Here, we applied a proph
Externí odkaz:
https://doaj.org/article/eac5a1c76e4a4c1983f6fdb028e98cf2
Autor:
Shelby, Renee, Rismani, Shalaleh, Henne, Kathryn, Moon, AJung, Rostamzadeh, Negar, Nicholas, Paul, Yilla, N'Mah, Gallegos, Jess, Smart, Andrew, Garcia, Emilio, Virk, Gurleen
Understanding the landscape of potential harms from algorithmic systems enables practitioners to better anticipate consequences of the systems they build. It also supports the prospect of incorporating controls to help minimize harms that emerge from
Externí odkaz:
http://arxiv.org/abs/2210.05791
Autor:
Ney, V., Henne, B., de Souza, M., Jantsch, W., Johansen, K. M., Wilhelm, F., Rogalev, A., Ney, A.
Ni incorporation has been studied in a comprehensive range of Zn/Co-based magnetic oxides to elucidate it valence state and lattice incorporation. The resulting structural and magnetic properties are studied in detail. To the one end Ni in incorporat
Externí odkaz:
http://arxiv.org/abs/2208.11086
Publikováno v:
Atmospheric Chemistry and Physics, Vol 24, Pp 2759-2782 (2024)
We present the first application of the ICOsahedral Nonhydrostatic model with Aerosols and Reactive Trace gases (ICON-ART) in inverse modeling in inverse modeling of greenhouse gas fluxes with an ensemble Kalman smoother. For this purpose, we extende
Externí odkaz:
https://doaj.org/article/92818d222a914adc89bd71dac935bec4
Autor:
I. Katharopoulos, D. Rust, M. K. Vollmer, D. Brunner, S. Reimann, S. J. O'Doherty, D. Young, K. M. Stanley, T. Schuck, J. Arduini, L. Emmenegger, S. Henne
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 14159-14186 (2023)
Inverse modeling is a widely used top-down method to infer greenhouse gas (GHG) emissions and their spatial distribution based on atmospheric observations. The errors associated with inverse modeling have multiple sources, such as observations and a
Externí odkaz:
https://doaj.org/article/523a6a57c8aa4cec9a65d83bfc8e08dc
Autor:
Sabrina Katrin Henne, Rana Aldisi, Sugirthan Sivalingam, Lara Maleen Hochfeld, Oleg Borisov, Peter Michael Krawitz, Carlo Maj, Markus Maria Nöthen, Stefanie Heilmann-Heimbach
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Male-pattern hair loss (MPHL) is common and highly heritable. While genome-wide association studies (GWAS) have generated insights into the contribution of common variants to MPHL etiology, the relevance of rare variants remains unclear. To
Externí odkaz:
https://doaj.org/article/a171b6aa33ba46fa9e50d5a3280cd103
Autor:
Katharina Roth, Maren Julia Pröll-Cornelissen, Hubert Henne, Anne Kathrin Appel, Karl Schellander, Ernst Tholen, Christine Große-Brinkhaus
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Immune traits are considered to serve as potential biomarkers for pig’s health. Medium to high heritabilities have been observed for some of the immune traits suggesting genetic variability of these phenotypes. Consideration of
Externí odkaz:
https://doaj.org/article/16947d685e2a41489abf066718ac52f1