Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Henna Pehkonen"'
Autor:
Henna Pehkonen, Artemis Filippou, Juho Väänänen, Iida Lindfors, Mira Vänttinen, Philipp Ianevski, Anne Mäkelä, Pauliina Munne, Juha Klefström, Sanna Toppila‐Salmi, Reidar Grénman, Jaana Hagström, Antti A. Mäkitie, Piia‐Riitta Karhemo, Outi Monni
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 662-676 (2024)
PTPRF interacting protein alpha 1 (PPFIA1) encodes for liprin‐α1, a member of the leukocyte common antigen–related protein tyrosine phosphatase (LAR‐RPTPs)‐interacting protein family. Liprin‐α1 localizes to adhesive and invasive structure
Externí odkaz:
https://doaj.org/article/5adbbe91f802423398c274eb66b71c64
Autor:
Henna Pehkonen, Mira Lento, Pernilla von Nandelstadh, Artemis Filippou, Reidar Grénman, Kaisa Lehti, Outi Monni
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background PPFIA1 is located at the 11q13 region commonly amplified in cancer. The protein liprin-α1 encoded by PPF1A1 contributes to the adhesive and invasive structures of cytoskeletal elements and is located at the invadosomes in cancer
Externí odkaz:
https://doaj.org/article/6d53bea9f8554a58bd0e4eb6d083ca1a
Publikováno v:
Oncogene
Liprins are a multifunctional family of scaffold proteins, identified by their involvement in several important neuronal functions related to signaling and organization of synaptic structures. More recently, the knowledge on the liprin family has exp
Autor:
Pernilla von Nandelstadh, Artemis Filippou, Outi Monni, Mira Lento, Henna Pehkonen, Kaisa Lehti, Reidar Grénman
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-14 (2018)
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-14 (2018)
Background PPFIA1 is located at the 11q13 region commonly amplified in cancer. The protein liprin-α1 encoded by PPF1A1 contributes to the adhesive and invasive structures of cytoskeletal elements and is located at the invadosomes in cancer cells. Ho
Autor:
Outi Monni, Reidar Grénman, Piia-Riitta Karhemo, Kaisa Lehti, Tatiana Lepikhova, Henna Pehkonen, Pernilla von Nandelstadh
Publikováno v:
Scientific Reports
PPFIA1 is located at the 11q13 region, which is one of the most commonly amplified regions in several epithelial cancers including head and neck squamous cell carcinoma and breast carcinoma. Considering the location of PPFIA1 in this amplicon, we exa
Autor:
Outi Monni, Riku Louhimo, Henna Heinonen, Gong-Hong Wei, Tatiana Lepikhova, Päivi Pihlajamaa, Ping Gao, Henna Pehkonen, Biswajyoti Sahu, Olli A. Jänne, Sampsa Hautaniemi
Publikováno v:
International Journal of Cancer
HOXB7 encodes a transcription factor that is overexpressed in a number of cancers and encompasses many oncogenic functions. Previous results have shown it to promote cell proliferation, angiogenesis, epithelial–mesenchymal transition, DNA repair an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68d135018c35d239c14bc580e214c20
http://hdl.handle.net/10138/208081
http://hdl.handle.net/10138/208081
Autor:
Riku Louhimo, Misa Imai, Juha Kleftsröm, Tatiana Lepikhova, Henna Pehkonen, Nina Peitsaro, Rafael S. Martinez, Sampsa Hautaniemi, Outi Monni
Publikováno v:
Cancer Research. 73:4933-4933
PPFIA1 (liprin α1) is a member of the liprin (LAR protein-tyrosine phosphatase-interacting protein) family and is located at the 11q13 amplification region, which is one of the most common amplicons in multiple epithelial cancers. In squamous cell c
Autor:
Tatiana Lepikhova, Juha Klefström, Henna Pehkonen, Nina Peitsaro, Sampsa Hautaniemi, Ping Chen, Outi Monni, Riku Louhimo, Misa Imai, Anni I. Nieminen
Publikováno v:
Cancer Research. 71:4963-4963
Gene amplification is one of the most common mechanisms for oncogenic activation in human cancer. Some genomic regions are more frequently amplified than others. For example, amplification of 11q13 occurs at high frequencies in several human cancers,