Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Henko Tadema"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24315 (2011)
INTRODUCTION: Toll-like receptors (TLRs) are a family of receptors that sense pathogen associated patterns such as bacterial cell wall proteins. Bacterial infections are associated with anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculi
Externí odkaz:
https://doaj.org/article/d11ee6c514ba4f80a12e175190ddaa60
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17972 (2011)
The etiology of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitides (AAV) is unknown, but the association between infections and autoimmunity has been studied extensively. In 2004, a novel theory was proposed that could link infecti
Externí odkaz:
https://doaj.org/article/53bfbc2ede014ebf80519851df8c83d3
Publikováno v:
Bioanalysis. 13(21)
As the number of therapeutic modalities expand, and the field of scientific research evolves toward finding treatment solutions for complex and rare disease, an ability to demonstrate efficacy through biomarker end points in clinical development stud
Autor:
Henko Tadema
Publikováno v:
Bioanalysis. 13:1585-1586
Autor:
Jay C. Strum, Rajesh K. Malik, Patrick J. Roberts, Ewoud Jan Van Hoogdalem, Henko Tadema, Hannah Storrie-White, Renger G. Tiessen, William A. Wargin, John E. Bisi, Shenghui He, Karenann M. Makhuli, Jessica A. Sorrentino, Norman E. Sharpless
Publikováno v:
Science Translational Medicine. 9
Conventional cytotoxic chemotherapy is highly effective in certain cancers, but causes dose-limiting damage to normal proliferating cells, especially hematopoietic stem and progenitor cells (HSPCs). Serial exposure to cytotoxics causes a long-term he
Autor:
Gürkan Sengölge, Renate Kain, Cees G. M. Kallenberg, Paul A. Lyons, Virginie Hubert, Andrea Peschel, Eoin F. McKinney, Tjerk Feenstra, Ricarda Brandes, Peter Heeringa, Kenneth G. C. Smith, Henko Tadema, Alexandra Benharkou, Coen A. Stegeman, Andrew J. Rees
Publikováno v:
Journal of the American Society of Nephrology, 23(3), 556-566. AMER SOC NEPHROLOGY
The involvement of autoantibodies to human lysosome-associated membrane protein-2 (hLAMP-2) in anti neutrophil cytoplasmic antibody (ANCA) associated vasculitis is controversial because of the absence of confirmatory data subsequent to the initial re
Publikováno v:
Current Opinion in Rheumatology. 23:366-371
Purpose of review Wegener's granulomatosis is associated with bacterial infection, in particular nasal carriage of Staphylococcus aureus. Infection may play a role in the induction of autoimmunity as well as in the effector phase of the disease. Here
Autor:
Cees G. M. Kallenberg, Peter Heeringa, Wayel H. Abdulahad, Henko Tadema, Coen A. Stegeman, Nikola Lepse
Publikováno v:
Rheumatology, 50(4), 689-696. Oxford University Press
Objectives. CpG motifs, which are highly prevalent in bacterial DNA, have been shown to trigger the production of ANCA in vitro by B lymphocytes from patients with active ANCA-associated vasculitis (AAV). Staphylococcus aureus is associated with rela
Autor:
Edo Vellenga, Simon Daenen, Hein Schepers, Szabolcs Fatrai, Henko Tadema, Jan Jacob Schuringa
Publikováno v:
Experimental Hematology, 36(10), 1254-1265. ELSEVIER SCIENCE INC
Objective. Mucin1 is a membrane glycoprotein that is overexpressed in a variety of human cancers. Here, we analyzed the role of Mucin1 in human hematopoietic stem/progenitor cells as well as in acute myeloid leukemia (AML) cells.Materials and Methods
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 3, p e17972 (2011)
PLoS ONE, 6(3):17972. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 6, Iss 3, p e17972 (2011)
PLoS ONE, 6(3):17972. PUBLIC LIBRARY SCIENCE
The etiology of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitides (AAV) is unknown, but the association between infections and autoimmunity has been studied extensively. In 2004, a novel theory was proposed that could link infecti