Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis

Autor: Basu Roy, Upal K., Henkhaus, Rebecca S., Loupakis, Fotios, Cremolini, Chiara, Gerner, Eugene W., Ignatenko, Natalia A.

Caveolin-1 is an essential component of membrane caveolae. It is an important regulator of cellular processes such as signal transduction and endocytosis. We report here, for the first time, that caveolin-1 is a target of the K-RAS oncogene in colon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a6c18e3259d3a8149fc6ecfe31c50e05
https://europepmc.org/articles/PMC3633716/

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Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways.

Autor: Padavano J; Department of Biochemistry and Molecular Biophysics, Undergraduate Biology Research Program, University of Arizona, Tucson, Arizona, USA., Henkhaus RS; Cancer Biology Interdisciplinary Program, University of Arizona Cancer Center, Tucson, AZ, USA., Chen H; University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA., Skovan BA; University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA., Cui H; University of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA., Ignatenko NA; Department of Cellular & Molecular Medicine, University of Arizona, Tucson, AZ, USA.

Publikováno v: Cancer growth and metastasis [Cancer Growth Metastasis] 2015 Oct 19; Vol. 8 (Suppl 1), pp. 95-113. Date of Electronic Publication: 2015 Oct 19 (Print Publication: 2015).