Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30

Autor: Bauke V. Schomakers, Nicole N. van der Wel, Rebecca L. McIntyre, Georges E. Janssens, Riekelt H. Houtkooper, Henk van der Veen, Ruedi Aebersold, Jiayi Lan, Pallas Yao, Alyson W. MacInnes, Evan G. Williams, Michel van Weeghel, William B. Mair, Yasmine J. Liu

Publikováno v: Journal of cell biology, 219(6):e201907067.. Rockefeller University Press
The Journal of Cell Biology
The Journal of Cell Biology, 219 (6)
Journal of Cell Biology

Mitochondrial form and function are closely interlinked in homeostasis and aging. Inhibiting mitochondrial translation is known to increase lifespan in C. elegans, and is accompanied by a fragmented mitochondrial network. However, whether this link b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf92aa06dfb07ea906a8e597121f5502
http://orbilu.uni.lu/handle/10993/48043

Melioidosis in travelers : An analysis of Dutch melioidosis registry data 1985–2018

Autor: Emma Birnie, Jelmer Savelkoel, Frans Reubsaet, Joris J.T.H. Roelofs, Robin Soetekouw, Saskia Kolkman, Anne Lia Cremers, Martin P. Grobusch, Daan W. Notermans, W. Joost Wiersinga, Wouter Rozemeijer, Annemieke Rijkeboer, Maarten Scholing, Karin van Dijk, Ellen M. Mascini, Henk van der Veen, Wouter van den Bijllaardt, Maaike de Vries, Leonard C. Smeets, Alewijn Ott, Kees van Krimpen, Bjorn L. Herpers, G. Hanke Watttel-Louis, Karola Waar, Noortje L.Q. Schwandt, Ianthe Maat, Anthonius S.M. Dofferhoff, Joost N. Vermeulen, Mireille van Westreenen, Peter de Man, Regina W. Hofland, Joost van Gorp, Steven Thijsen, Lieven B. van der Velden, Cornelis M. Verduin

Publikováno v: Travel Medicine and Infectious Disease, 32. Elsevier USA
Travel Medicine and Infectious Disease, 32
Tropical medicine and infectious disease, 32:101461. Elsevier Inc.
Travel medicine and infectious disease, 32:101461. Elsevier USA

Background: Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an opportunistic infection across the tropics. Here, we provide a systematic overview of imported human cases in a non-endemic country over a 25-year period.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d253ea96be7bc15ca3ff611ebb0e23
https://dspace.library.uu.nl/handle/1874/389254

Efficacy of cognitive behavioral therapy and physical exercise in alleviating treatment-induced menopausal symptoms in patients with breast cancer: results of a randomized, controlled, multicenter trial

Autor: Hester S. A. Oldenburg, Herman Rijna, Gert-Jan Timmers, Martijn M. Stuiver, Marian B. E. Menke-Pluymers, Jacobien M. Kieffer, Louise M. de Widt-Levert, Henk van der Veen, Maud M. Geenen, Miranda A. Gerritsma, Epie Boven, Gijsbert Heuff, Eric J van Dulken, Myra S. Hunter, Nina Bijker, Saskia F. A. Duijts, Suzan van der Meij, Neil K. Aaronson, Marc van Beurden, Peter W. Plaisier, Alexander M F Lopes Cardozo

Publikováno v: Journal of clinical oncology, 30(33), 4124-4133. American Society of Clinical Oncology
Journal of Clinical Oncology, 30(33), 4124-4133. American Society of Clinical Oncology
Duijts, S F A, van Beurden, M, Oldenburg, H S, Hunter, M S, Kieffer, J M, Stuiver, M M, Gerritsma, MA, Menke-Pluymers, M B E, Plaisier, P W, Rijna, H, Cardozo, A M F L, Timmers, G, van der Meij, S, van der Veen, H, Bijker, N, de Widt-Levert, L M, Geenen, M M, Heuff, G, van Dulken, E J, Boven, E & Aaronson, N K 2012, ' Efficacy of Cognitive Behavioral Therapy and Physical Exercise in Alleviating Treatment-Induced Menopausal Symptoms in Patients With Breast Cancer: Results of a Randomized, Controlled, Multicenter Trial ', Journal of Clinical Oncology, vol. 30, no. 33, pp. 4124-4133 . https://doi.org/10.1200/JCO.2012.41.8525

Purpose The purpose of our study was to evaluate the effect of cognitive behavioral therapy (CBT), physical exercise (PE), and of these two interventions combined (CBT/PE) on menopausal symptoms (primary outcome), body image, sexual functioning, psyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8697d84e0957348567dee6ada66ea4
https://dare.uva.nl/personal/pure/en/publications/efficacy-of-cognitive-behavioral-therapy-and-physical-exercise-in-alleviating-treatmentinduced-menopausal-symptoms-in-patients-with-breast-cancer-results-of-a-randomized-controlled-multicenter-trial(a84feaae-7ae3-45b8-ae7d-292f17a37fd3).html

Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial

Autor: M. Petrousjka van den Tol, S. Muller, Roos H de Wit, Alexander M F Lopes Cardozo, Louise M. de Widt-Levert, A.M. Bosch, Elly S.M. de Lange-de Klerk, Sybren L. Meijer, E. Bergers, M.H. Haloua, Henk van der Veen, N.M.A. Krekel

Publikováno v: Krekel, N M A, Haloua, M H, Cardozo, A M F L, de Wit, R H, Bosch, A M, de Widt-Levert, L M, Muller, S, van der Veen, H, Bergers, E, de Lange-de Klerk, E S M, Meijer, S & van den Tol, M P 2013, ' Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial ', Lancet Oncology, vol. 14, no. 1, pp. 48-54 . https://doi.org/10.1016/S1470-2045(12)70527-2
Lancet Oncology, 14(1), 48-54. Lancet Publishing Group

Summary Background Breast-conserving surgery for palpable breast cancer is associated with tumour-involved margins in up to 41% of cases and excessively large excision volumes. Ultrasound-guided surgery has the potential to resolve both of these prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f1684da5a5fd6aad01396f5fcc5f5b
https://pubmed.ncbi.nlm.nih.gov/23668704

Ultrasound-guided breast-sparing surgery to improve cosmetic outcomes and quality of life. A prospective multicentre randomised controlled clinical trial comparing ultrasound-guided surgery to traditional palpation-guided surgery (COBALT trial)

Autor: Louise de Widt, Wilfred K de Roos, E. Bergers, Sybren L. Meijer, Elly S.M. de Lange-de Klerk, S. Muller, B.M. Zonderhuis, Henk van der Veen, Pieter Poortman, Annette H. M. Taets van Amerongen, A.M. Bosch, Nicole M. A. Krekel, Alexander M F Lopes Cardozo, Mecheline H M van der Linden, Herman Rijna, Petrousjka van den Tol, Hermien Schreurs, Henri A. H. Winters

Publikováno v: BMC Surgery, Vol 11, Iss 1, p 8 (2011)
BMC Surgery, 11:8. BioMed Central
Krekel, N M A, Zonderhuis, B M, Schreurs, H W H, Cardozo, A M F L, Rijna, H, van der Veen, H, Muller, S, Poortman, P, Widt, L, de Roos, W K, Bosch, A M, Taets van amerongen, A H M, Bergers, E, van der Linden, M H M, de Klerk, E S M, Winters, H A H, Meijer, S & van den Tol, M P 2011, ' Ultrasound-guided breast-sparing surgery to improve cosmetic outcomes and quality of life. A prospective multicentre randomised controlled clinical trial comparing ultrasound-guided surgery to traditional palpation-guided surgery (COBALT trial) ', BMC Surgery, vol. 11, 8 . https://doi.org/10.1186/1471-2482-11-8
BMC Surgery

Background Breast-conserving surgery for breast cancer was developed as a method to preserve healthy breast tissue, thereby improving cosmetic outcomes. Thus far, the primary aim of breast-conserving surgery has been the achievement of tumour-free re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a5215219dd7c35cd7abde2715757a5
http://www.biomedcentral.com/1471-2482/11/8