Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Henk Van Liempt"'
Publikováno v:
Biotechnology: Products of Secondary Metabolism, Volume 7, Second Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d51eda34f1e35b2f9f753d98f5debae
https://doi.org/10.1002/9783527620999.ch6g
https://doi.org/10.1002/9783527620999.ch6g
Autor:
Hans-Jochen Schaefer, Maja Pavela-Vrančić, Horst Kleinkauf, Eva Pfeifer, Hans von Doehren, Henk van Liempt
Publikováno v:
Biochemistry. 33:6276-6283
Characterization of the nucleotide binding domain in peptide synthetases was approached by photoaffinity labeling of tyrocidine synthetase 1 (TY1) with 2-azidoadenosine triphosphate (2-azido-ATP). Exposure of TY1 in the presence of photolabel to irra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958167da0d1820c605aa520ba1dc93ff
https://doi.org/10.1021/bi00186a030
https://doi.org/10.1021/bi00186a030
Autor:
Henk van Liempt, Horst Kleinkauf, H. Palissa, Torsten Schwecke, Hans von Döhren, Yair Aharonowitz
Publikováno v:
European Journal of Biochemistry. 205:687-694
delta-(L-alpha-Aminoadipyl)-L-cysteinyl-D-valine (ACV) synthetase, the multienzyme catalyzing the formation of ACV from the constituent amino acids and ATP in the presence of Mg2+ and dithioerythritol, was purified about 2700-fold from Streptomyces c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a63c9bdaf09b1d45ba9f7f25e21250
https://doi.org/10.1111/j.1432-1033.1992.tb16830.x
https://doi.org/10.1111/j.1432-1033.1992.tb16830.x
Publikováno v:
FEBS letters. 357(2)
Peptide synthetases and acyl-CoA-synthetases form acyl adenylates which are transferred to CoA or enzyme-bound pantetheine. To verify the existence of an adenylate domain in peptide synthetases, a 60.8 kDa fragment of tyrocidine 1-synthetase was cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72010c9a7b2777adec7b81e5a48d7196
https://pubmed.ncbi.nlm.nih.gov/7805893
https://pubmed.ncbi.nlm.nih.gov/7805893
Publikováno v:
European journal of biochemistry. 220(2)
Peptide synthetases consist of linearly arranged catalytic units, which by sequence alignment show equally spaced amino-acid-activating segments/modules of 600–700 amino acid residues. The consensus sequence comprises a new class of sequence motifs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1251416f2a170a55df9f2cd2943bbe
https://pubmed.ncbi.nlm.nih.gov/8125112
https://pubmed.ncbi.nlm.nih.gov/8125112
Autor:
Yair Aharonowitz, Jürgen Bergmeyer, Jesus M. Cantoral, Gerald Cohen, Arnold L. Demain, Uwe Fink, Jim Kinghorn, Horst Kleinkauf, Andrew MacCabe, Harriet Palissa, Eva Pfeifer, Torsten Schwecke, Henk van Liempt, Hans von Döhren, Saul Wolfe, Jinyou Zhang
Publikováno v:
Bio/technology (Nature Publishing Company). 11(7)
ACV synthetase forms the tripeptide precursor of penicillins and cephalosporins from alpha-aminoadipate, cysteine, and valine. Catalytic sites for substrate carboxyl activation as adenylates, peptide bond formations, epimerization and release of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bde24e1fe4e1e9450fce03c8dfbfa9
https://pubmed.ncbi.nlm.nih.gov/7763859
https://pubmed.ncbi.nlm.nih.gov/7763859