Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Henk M, Jansen"'
Autor:
René Lutter, Martin Boorsma, Marianne A. van de Pol, Theo A. Out, René E. Jonkers, Henk M. Jansen
Publikováno v:
COPD, 4(4), 321-329. Informa Healthcare
RATIONALE: Limited information is available on repeatability of inflammatory parameters in whole induced sputum samples from patients with COPD. OBJECTIVES: To study short-term and long-term repeatability in induced sputum samples in 22 patients with
Autor:
Paul Bresser, Henk M. Jansen, Jaap J. Kloek, Jim A. Reekers, Herre J. Reesink, Otto M. van Delden
Publikováno v:
CardioVascular and Interventional Radiology. 30:136-139
Hemoptysis is a known complication in patients with bronchial artery hypertrophy due to a variety of chronic pulmonary disorders. Bronchial artery hypertrophy is observed in most patients with chronic thromboembolic pulmonary hypertension (CTEPH), bu
Publikováno v:
FEMS Microbiology Letters. 156:165-170
Since the ability of bacteria to compete with lactoferrin for iron contributes to the pathogenesis of mucosal infections, the presence of lactoferrin receptor activity in non-encapsulated Haemophilus influenzae was investigated. The growth of 18 H. i
Autor:
Tom van der Poll, Sandrine Florquin, René Lutter, Johannes H.M. Levels, Koenraad F. van der Sluijs, Monique Nijhuis, Henk M. Jansen, Andrew L. Mellor
Publikováno v:
Journal of infectious diseases, 193(2), 214-222. Oxford University Press
Background Airway infection with influenza virus induces local expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO), which has been shown to enhance inflammatory mediator responses in vitro. Because secondary pneumococca
Autor:
Henk M. Jansen, J.S. van der Zee, A. F. de Vos, Paul Bresser, C. A. Spek, Nico A. Maris, Mark C. Dessing, T. van der Poll
Publikováno v:
European respiratory journal, 28(3), 622-626. European Respiratory Society
Toll-like receptors (TLRs) are pattern-recognition receptors that have been implicated in the initiation of innate immune responses upon the first encounter with invading pathogens. The airways are frequently exposed to various types of lipopolysacch
Autor:
Filiz Keles, Mieke Snoek, René Lutter, Henk M. Jansen, Jan van Marle, Jaime Freitas, Arjen van den Berg
Publikováno v:
Experimental cell research, 312(9), 1496-1506. Academic Press Inc.
Airway epithelial cells are critically dependent on an intact cytoskeleton for innate defense functions. There are various pathophysiological conditions that affect the cytoskeletal architecture. We studied the effect of cytoskeletal distortion in po
Autor:
W Bronsveld, F Vlaspolder, T Groot, C. S. de Graaff, M M van der Eerden, Wim Boersma, Henk M. Jansen
Publikováno v:
Thorax, 60(8), 672-678. BMJ Publishing Group
Background: There is much controversy about the ideal approach to the management of community acquired pneumonia (CAP). Recommendations differ from a pathogen directed approach to an empirical strategy with broad spectrum antibiotics. Methods: In a p
Publikováno v:
European journal of clinical microbiology & infectious diseases, 24(4), 241-249. Springer Verlag
In a prospective study to evaluate the diagnostic yield of different microbiological tests in hospitalised patients with community-acquired pneumonia, material for microbiological investigation was obtained from 262 patients. Clinical samples consist
Autor:
Henk M. Jansen, Leontine J. R. van Elden, René Lutter, Koenraad F. van der Sluijs, Ramon Arens, Monique Nijhuis, Rob Schuurman, Shizuo Akira, Sandrine Florquin, Tom Van Der Polls, Joan Kwakkel
Publikováno v:
Immunology
Immunology, 114(1), 112-120. Wiley-Blackwell
Immunology, 114(1), 112-120. Wiley-Blackwell
T helper 1 driven immune responses facilitate host defence during viral infections. Because interleukin-18 (IL-18) mediates T helper 1 driven immune responses, and since mature IL-18 is up-regulated in human macrophages after influenza virus infectio
Autor:
Theo A. Out, Ester M. M. van Leeuwen, René A. W. van Lier, Godelieve J. de Bree, René E. Jonkers, Henk M. Jansen
Publikováno v:
Journal of experimental medicine, 202(10), 1433-1442. Rockefeller University Press
The Journal of Experimental Medicine
Journal of Experimental Medicine, 202(10), 1433-1442. Rockefeller University Press
The Journal of Experimental Medicine
Journal of Experimental Medicine, 202(10), 1433-1442. Rockefeller University Press
The lungs are frequently challenged by viruses, and resident CD8+ T cells likely contribute to the surveillance of these pathogens. To obtain insight into local T cell immunity to respiratory viruses in humans, we determined the specificity, phenotyp