An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands

Autor: Astrid S. Bulder, A.A.M. Gerritsen, Guy C. M. Grinwis, Jacob de Boer, Juliette Legler, Willie J.G.M. Peijnenburg, G.B.J. Rijs, Joost Lahr, Henk J. M. Verhaar, Raoul V. Kuiper, A.C. Belfroid, A. Dick Vethaak, Tinka A.J. Murk, S. Marca Schrap, Pim de Voogt

Publikováno v: Chemosphere, 59, 511-524. Elsevier
Chemosphere 59 (2005) 4
Chemosphere, 59(4), 511-524
Vethaak, A D, Lahr, J, Schrap, S M, Belfroid, A C, Rijs, G B J, Gerritsen, A, de Boer, J, Bulder, A S, Grinwis, G C M, Kuiper, R V, Legler, J, Murk, T A J, Peijnenburg, W, Verhaar, H J M & de Voogt, P 2005, ' An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands ', Chemosphere, vol. 59, no. 4, pp. 511-524 . https://doi.org/10.1016/j.chemosphere.2004.12.053
Chemosphere, 59(4), 511-524. Elsevier Limited

An extensive study was carried out in the Netherlands on the occurrence of a number of estrogenic compounds in surface water, sediment, biota, wastewater, rainwater and on the associated effects in fish. Compounds investigated included natural and sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec22f525a4f202e524a41fd47109c51
https://doi.org/10.1016/j.chemosphere.2004.12.053

Comparing the Potency of Chemicals with Multiple Modes of Action in Aquatic Toxicology: Acute Toxicity Due to Narcosis versus Reactive Toxicity of Acrylic Compounds

Autor: Andreas P. Freidig, Joop L. M. Hermens, Henk J. M. Verhaar

Publikováno v: Environmental Science & Technology. 33:3038-3043

A series of acrylates and methacrylates was used to illustrate a strategy to compare the importance of two modes of action (MOA) and thereby identify the predominant cause of acute fish toxicity. Acrylic compounds are known to be Michael acceptors an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bc0146ca3388f1e3bfd4fb4649ec9fc
https://doi.org/10.1021/es990251b

An LC50 vs Time Model for the Aquatic Toxicity of Reactive and Receptor-Mediated Compounds. Consequences for Bioconcentration Kinetics and Risk Assessment

Autor: Karin C. H. M. Legierse, Scott D. Dyer, Watze de Wolf, Willem Seinen, Joop L. M. Hermens, Henk J. M. Verhaar

Publikováno v: Environmental Science & Technology. 33:758-763

For aquatic toxicants that act by so-called nonpolar narcosis, it is generally acknowledged that the Critical Body Residue (CBR) at death, as a surrogate dose metric for the amount of target that has interacted with the toxicant, is constant. This co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6eccdad7bd13bb6c848c37d6d50d895d
https://doi.org/10.1021/es980507y

Using Solid-Phase Microextraction To Determine Partition Coefficients to Humic Acids and Bioavailable Concentrations of Hydrophobic Chemicals

Autor: Henk J. M. Verhaar, Wouter H. J. Vaes, Sandra N. Meijer, Joop L. M. Hermens, Eñaut Urrestarazu Ramos

Publikováno v: Environmental Science & Technology. 32:3430-3435

In the current study, the suitability of negligible depletion solid-phase microextraction (nd-SPME) to determine free fractions of chemicals in aquatic environments was explored. The potential interferences of the dissolved matrix (i.e., humic acids)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b94ac0b0bc9b8ec97b8a9322c5bfca8a
https://doi.org/10.1021/es980274a

Understanding and Estimating Membrane/Water Partition Coefficients: Approaches To Derive Quantitative Structure Property Relationships

Autor: Joop L. M. Hermens, Christopher J. Cramer, Wouter H. J. Vaes, Henk J. M. Verhaar, Eñaut Urrestarazu Ramos

Publikováno v: Chemical Research in Toxicology. 11:847-854

In the current study we describe three approaches to derive quantitative structure property relationships (QSPRs) that give insight in the interactions that are important in membrane/water partitioning. In the first model only semiempirically (AM1) c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d5988c7148acddcb7e8e9ba56b54c4
https://doi.org/10.1021/tx970210y