Zobrazeno 1 - 10 of 85 pro vyhledávání: '"Henk E.D.J. ter Keurs"'
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Akademický článek
Alternative Approaches to the Assessment of the Systemic Circulation and Left Ventricular Performance: A Proof-of-Concept Study
Autor: Sarah Howell, BSc, MSc, Lindsay M. Burrowes, BEng (Mech), MD, PhD, Israel Belenkie, MD, Henk E.D.J. ter Keurs, MD, PhD, Lucy Lei, BHSc, Satish R. Raj, MD, MSCI, J. Christopher Bouwmeester, BEng (Mech), PhD, Robert S. Sheldon, MD, PhD, Nigel G. Shrive, PhD, John V. Tyberg, MD, PhD
Publikováno v: CJC Open, Vol 1, Iss 2, Pp 84-92 (2019)
Background: The purpose of this article is to examine the systemic circulation and left ventricular (LV) performance by alternative, nonconventional approaches: systemic vascular conductance (GSV) and the head-capacity relation (ie, the relation betw
Externí odkaz: https://doaj.org/article/eb9ea06841d740ac9311c5a78be1fade
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3
Alternative Approaches to the Assessment of the Systemic Circulation and Left Ventricular Performance: A Proof-of-Concept Study
Autor: Henk E.D.J. ter Keurs, Nigel G. Shrive, John V. Tyberg, Satish R. Raj, Lucy Y. Lei, Israel Belenkie, Robert S. Sheldon, J. Christopher Bouwmeester, Sarah Howell, Lindsay M. Burrowes
Publikováno v: CJC Open, Vol 1, Iss 2, Pp 84-92 (2019)
CJC Open
Background: The purpose of this article is to examine the systemic circulation and left ventricular (LV) performance by alternative, nonconventional approaches: systemic vascular conductance (GSV) and the head-capacity relation (ie, the relation betw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa8b89f0e967ec9025af7300d6042dc
http://www.sciencedirect.com/science/article/pii/S2589790X19300083
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4
Cardiovascular risk is associated with a transmural gradient of myocardial oxygenation during adenosine infusion
Autor: Matthias G. Friedrich, Henk E.D.J. ter Keurs, Judy M. Luu, Jacqueline Flewitt, Anna Schmidt, Yoko Mikami
Publikováno v: European Heart Journal - Cardiovascular Imaging. 20:1287-1295
Aims In patients with coronary artery disease (CAD), a transmural gradient of myocardial perfusion has been repeatedly observed, with the subendocardial layer showing more pronounced perfusion deficits. Oxygenation-sensitive cardiovascular magnetic r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199268217f5e141471d979147096224e
https://doi.org/10.1093/ehjci/jey202
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5
Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation
Autor: Bo Sun, Andrew K. J. Boyce, Grant R. Gordon, Roger J. Thompson, Henk E.D.J. ter Keurs, Florian Hiess, Jinjing Yao, Wenting Guo, Mingke Ni, Ray W. Turner, Zhenpeng Song, Thomas G. Back, S.R. Wayne Chen, Xiaoqin Zhan, Yajing Liu, Adam Institoris, Michael Fill, Ruiwu Wang
Publikováno v: Cell Reports, Vol 32, Iss 12, Pp 108169-(2020)
Summary: Neuronal hyperactivity is an early primary dysfunction in Alzheimer’s disease (AD) in humans and animal models, but effective neuronal hyperactivity-directed anti-AD therapeutic agents are lacking. Here we define a previously unknown mode
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e0b0b547d96a2d619185b15b400042
https://pubmed.ncbi.nlm.nih.gov/33444912
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Distribution and Function of Cardiac Ryanodine Receptor Clusters in Live Ventricular Myocytes
Autor: Leif Hove-Madsen, Hongqiang Cheng, Florian Hiess, Raul Benitez, Alexander Vallmitjana, Ruiwu Wang, S. R. Wayne Chen, Henk E.D.J. ter Keurs, Ju Chen
Publikováno v: JOURNAL OF BIOLOGICAL CHEMISTRY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Recercat. Dipósit de la Recerca de Catalunya
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
The Journal of biological chemistry, vol 290, iss 33
The cardiac Ca(2+) release channel (ryanodine receptor, RyR2) plays an essential role in excitation-contraction coupling in cardiac muscle cells. Effective and stable excitation-contraction coupling critically depends not only on the expression of Ry
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c9f885e4ecfe57bcc862a44ab4bc3c
https://doi.org/10.1074/jbc.m115.650531
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8
Evoked centripetal Ca2+mobilization in cardiac Purkinje cells: insight from a model of three Ca2+release regions
Autor: Bruno D. Stuyvers, Masahito Miura, Rebecca E. Daniels, Henk E.D.J. ter Keurs, Lawson Miller, Kazi T. Haq, Sharene D. Bungay
Publikováno v: The Journal of Physiology. 591:4301-4319
Key points • Abnormal oscillations of calcium (Ca2+) concentration in cardiac Purkinje cells (P-cells) have been associated with life-threatening arrhythmias, but the mechanism by which these cells control their Ca2+ level in normal conditions rema
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c034cb8d3e601e4829465ae8f4ac212e
https://doi.org/10.1113/jphysiol.2013.253583
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9
Electromechanical coupling in the cardiac myocyte; stretch-arrhythmia feedback
Autor: Henk E.D.J. ter Keurs
Publikováno v: Pflügers Archiv - European Journal of Physiology. 462:165-175
The macroscopic hallmarks of the normal heartbeat are rapid onset of contraction and rapid relaxation and an inotropic response to both increased end diastolic volume and increased heart rate. At the microscopic level, the calcium ion (Ca(2+)) plays
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2b1f756f24bc852cb3ee26d154fce0
https://doi.org/10.1007/s00424-011-0944-3
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10
Nonuniform activation and the mechanics of myocardial trabeculae with fast or slow myosin
Autor: Henk E.D.J. ter Keurs, Ni Diao, Nathan P. Deis
Publikováno v: Annals of the New York Academy of Sciences. 1188:165-176
Left ventricular (LV) wall motion abnormalities reflect regional nonuniform contraction which may be arrhythmogenic. We studied sarcomere mechanics and force development (F) in uniform and nonuniform trabeculae using a model in which half of the musc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b2b4d48f873dfa7ebc5137376936cea
https://doi.org/10.1111/j.1749-6632.2009.05097.x
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