Výsledky vyhledávání - "Henk A. J. M. Hubers"

T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis–associated and nonassociated HLA–DR4 alleles

Autor: Grete Sønderstrup, Andrew P. Cope, GF Verheijden, Frances Hall, Rajasree Menon, Antonius W. M. Rijnders, Mauro Congia, Henk A. J. M. Hubers, Massimo Trucco, Salil D. Patel, Annemieke M. H. Boots

Publikováno v: Arthritis & Rheumatism. 42:1497-1507

Objective. To analyze the CD4+ T cell responses to the human cartilage antigen glycoprotein-39 (HCgp-39) in the context of rheumatoid arthritis (RA)-associated (DR alpha beta 1*0401) and nonassociated (DR alpha beta 1*0402) HLA class II molecules. Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f54b34607fbce53a93ff97c4974a240
https://doi.org/10.1002/1529-0131(199907)42:7<1497::aid-anr25>3.0.co

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Efficient generation of monoclonal antibodies from preselected antigenspecific B cells

Autor: Antonius W. M. Rijnders, Peter G. A. Steenbakkers, Henk A. J. M. Hubers

Publikováno v: Molecular Biology Reports. 19:125-134

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da465f11adc481408ca4a1f4653057a
https://doi.org/10.1007/bf00997158

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Identification of colon-tumor-associated antigens by T-cell lines derived from tumor-infiltrating lymphocytes and peripheral-blood lymphocytes from patients immunized with an autologous tumor-cell/bacillus calmette-Guérin vaccine

Autor: Nicholas Pomato, Henk A. J. M. Hubers, Janet H. Ransom, Michael G. Hanna, Linette M. Keynton, Barbara A. Pelle

Publikováno v: International Journal of Cancer. 54:734-740

Tumor immunity developing as a response to an autologous colon-tumor/bacillus Calmette-Guérin (BCG) vaccine appears to be associated with induction of CD4+ helper T cells, implied by the observation that vaccine efficacy is associated with major his

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4b8f3e1f73458bcb72c217e07b3df0
https://doi.org/10.1002/ijc.2910540505

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Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263–275) epitope: an MHC anchor variant peptide for immune modulation

Autor: Cindy van Doorn, Cornelis Marius Timmers, Annemieke M. H. Boots, Henk A. J. M. Hubers, Catharina J. van Staveren, Rachel Stenger, Bernice M. Westrek-Esselink, GF Verheijden, Leontien den Hoed-van Zandbrink, E Bos, Marie Jose C. van Lierop, Milou Kouwijzer

Publikováno v: Arthritis Research & Therapy

We sought to identify an altered peptide ligand (APL) based on the endogenously expressed synovial auto-epitope of human cartilage glycoprotein-39 (HC gp-39) for modulation of cognate, HLA-DR4-restricted T cells. For this purpose we employed a panel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfa27d8398782075111bfab85916e99
https://doi.org/10.1186/ar2269

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