Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Henk A Tennekes"'
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 17, Iss 5, p 1629 (2020)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health
Our mechanistic understanding of the toxicity of chemicals that target biochemical and/or physiological pathways, such as pesticides and medical drugs is that they do so by binding to specific molecules. The nature of the latter molecules (e.g., enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33576e82f82cf73e6bbce5b7540e278
https://www.mdpi.com/1660-4601/17/5/1629
https://www.mdpi.com/1660-4601/17/5/1629
Autor:
Henk A Tennekes
Publikováno v:
Journal of Toxicology and Environmental Health, Part B. 21:1-4
A recent quantitative weight of evidence (QWoE) assessment of higher tier studies on the toxicity and risks of neonicotinoids in honeybees by Solomon and Stephenson reported a colony-level no-observed-adverse effect concentration (NOAEC) of 25 µg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02ed4dde7f3e4be972e20830c6593486
https://doi.org/10.1080/10937404.2017.1421425
https://doi.org/10.1080/10937404.2017.1421425
Autor:
Henk A. Tennekes
Publikováno v:
Environmental Risk Assessment and Remediation.
Expenditure for discovery and development of a new crop protection product is now approaching the $ 300 million mark, while at the same time underpinning information gaps in environmental safety assessment. Large information gaps also exist for the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9529876c89136453df1fab0ba33518e4
https://doi.org/10.4066/2529-8046.100011
https://doi.org/10.4066/2529-8046.100011
Publikováno v:
Environmental Risk Assessment and Remediation.
The widespread contamination of a significant proportion of the planet’s land and water with pesticides is undeniable. While this takes place, innumerable species of animals associated with agricultural landscapes are declining at rates that may pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21e56ae6c20251da8048c27894cce523
https://doi.org/10.4066/2529-8046.100025
https://doi.org/10.4066/2529-8046.100025
Autor:
Henk A. Tennekes
Publikováno v:
Environmental Risk Assessment and Remediation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad954c43d1b2457174a7b262bf8d028c
https://doi.org/10.4066/2529-8046.1000e101
https://doi.org/10.4066/2529-8046.1000e101
Publikováno v:
Toxicology.
A latency period preceding neurotoxicity is a common characteristic in the dose-response relationship induced by organic mercury. Latency periods have typically been observed with genotoxicants in carcinogenesis, with cancer being manifested a long t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7381b6796974c3164a755c98908276e2
https://pubmed.ncbi.nlm.nih.gov/26945727
https://pubmed.ncbi.nlm.nih.gov/26945727
Autor:
Henk A. Tennekes
Publikováno v:
Journal of Environmental & Analytical Toxicology. 6
Most regulatory agencies assume that there is no safe level of exposure to carcinogens but that a threshold, or “safe” exposure level exists for non-carcinogens. However, recent discoveries have cast serious doubt on the validity of this concept.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870895380b02041bfa2ce238d23bc593
https://doi.org/10.4172/2161-0525.1000408
https://doi.org/10.4172/2161-0525.1000408
Publikováno v:
Internal Medicine Review.
Two dose response models have traditionally been used in risk assessment. Most regulatory agencies assume that there is no safe level of exposure to carcinogens but that a threshold, or “safe” exposure level exists for non-carcinogens. However, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4a72d44f4f94255b4b193ab2172be4b
https://doi.org/10.18103/imr.v0i2.28
https://doi.org/10.18103/imr.v0i2.28
Autor:
Henk A. Tennekes
Publikováno v:
Toxicology. 276:1-4
The essence of the Druckrey-Kupfmuller equation dtn = constant (where d = daily dose and t = exposure time-to-effect, with n > 1) for chemical carcinogens is that the total dose required to produce the same effect decreases with decreasing exposure l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df0959ff0ecb30fee4974065fae16bbc
https://doi.org/10.1016/j.tox.2010.07.005
https://doi.org/10.1016/j.tox.2010.07.005
Publikováno v:
Toxicity and Hazard of Agrochemicals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77649c07274c081b781fc87e67f13a16
https://doi.org/10.5772/60739
https://doi.org/10.5772/60739
