Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hengxu Mao"'
Autor:
Hengxu Mao, Yaoyun Kuang, Du Feng, Xiang Chen, Lin Lu, Wencheng Xia, Tingting Gan, Weimeng Huang, Wenyuan Guo, Hancun Yi, Yirong Yang, Zhuohua Wu, Wei Dai, Hui Sun, Jieyuan Wu, Rui Zhang, Shenqing Zhang, Xiuli Lin, Yuxuan Yong, Xinling Yang, Hongyan Li, Wenjun Wu, Xiaoyun Huang, Zhaoxiang Bian, Hoi Leong Xavier Wong, Xin-Lu Wang, Michael Poppell, Yi Ren, Cong Liu, Wen-Quan Zou, Shengdi Chen, Ping-Yi Xu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract Background Seed amplification assays (SAA) enable the amplification of pathological misfolded proteins, including α-synuclein (αSyn), in both tissue homogenates and body fluids of Parkinson’s disease (PD) patients. SAA involves repeated
Externí odkaz:
https://doaj.org/article/d23c5a987e634c22a6f7e6300ff16365
Autor:
Yaoyun Kuang, Hengxu Mao, Tingting Gan, Wenyuan Guo, Wei Dai, Weimeng Huang, Zhuohua Wu, Hongyan Li, Xiaoyun Huang, Xinling Yang, Ping-Yi Xu
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The seeding amplification assay (SAA) has recently emerged as a valuable tool for detecting α-synuclein (αSyn) aggregates in various clinically accessible biospecimens. Despite its efficiency and specificity, optimal tissue-specific condit
Externí odkaz:
https://doaj.org/article/075d674c1c034a1086cf9f207916014a
Autor:
Lin Lu, Hengxu Mao, Miaomiao Zhou, Yuwan Lin, Wei Dai, Jiewen Qiu, Yousheng Xiao, Mingshu Mo, Xiaoqin Zhu, Zhuohua Wu, Zhong Pei, Wenyuan Guo, Pingyi Xu, Xiang Chen, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 13, Pp 1588-1596 (2022)
Background:. Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Mitochondrial dysfunction is involved in the pathology of PD. Coiled-coil-helix-coiled-coil-helix domain-containing 2 (CHCHD2) was i
Externí odkaz:
https://doaj.org/article/73955be826874c989ba386e63d922a43
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The intracellular aggregation of α-synuclein in neurons/glia is considered to be a key step in the pathogenesis of synucleinopathy [including Parkinson’s disease (PD), dementia with Lewy body (DLB), multiple system atrophy (MSA), etc.]. Increasing
Externí odkaz:
https://doaj.org/article/65f75dbb11d34aa88f75a6b60461805d
Autor:
Shuxuan Huang, Hanqun Liu, Yuwan Lin, Muchang Liu, Yanhua Li, Hengxu Mao, Zhiling Zhang, Yunlong Zhang, Panghai Ye, Liuyan Ding, Ziting Zhu, Xinling Yang, Chaojun Chen, Xiaoqin Zhu, Xiaoyun Huang, Wenyuan Guo, Pingyi Xu, Lin Lu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
The NLR family pyrin domain containing 3 (NLRP3) inflammasome was reported to be regulated by autophagy and activated during inflammatory procession of Parkinson’s disease (PD). Berberine (BBR) is well-studied to play an important role in promoting
Externí odkaz:
https://doaj.org/article/8af50fd0ffdc469fa2b1b071cd82916e
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-19 (2018)
Abstract Background Parkinson’s disease (PD) is the most prevalent neurodegenerative disorder that is characterised by selective loss of midbrain dopaminergic (DA) neurons. Chronic inflammation of the central nervous system is mediated by microglia
Externí odkaz:
https://doaj.org/article/7070343d1d1d415582a9d12918838e55
Autor:
Wenlong Zhang, Liuyan Ding, Mengran Zhang, Shaohui Zheng, Runfang Ma, Junwei Gong, Hengxu Mao, Huaxi Xu, Pingyi Xu, Yunlong Zhang
Publikováno v:
Cellular and Molecular Life Sciences. 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2684d5dd217598aa941d999a4f1c43a6
https://doi.org/10.1007/s00018-023-04807-7
https://doi.org/10.1007/s00018-023-04807-7
Autor:
Baoyan Wang, Shizhong Zhang, Hongbo Zhang, Guohui Lu, Yongyi Ye, Hengxu Mao, Xiang Sun, Longping Yao, Chen Qian
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 12, Pp 2521-2527 (2021)
Neural Regeneration Research, Vol 16, Iss 12, Pp 2521-2527 (2021)
The expression of major histocompatibility complex class I (MHC-I), a key antigen-presenting protein, can be induced in dopaminergic neurons in the substantia nigra, thus indicating its possible involvement in the occurrence and development of Parkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fd95040777ba1fdb1259bb7d96e12b
http://europepmc.org/articles/PMC8374590
http://europepmc.org/articles/PMC8374590
Autor:
Lin Lu, Hengxu Mao, Miaomiao Zhou, Yuwan Lin, Wei Dai, Jiewen Qiu, Yousheng Xiao, Mingshu Mo, Xiaoqin Zhu, Zhuohua Wu, Zhong Pei, Wenyuan Guo, Pingyi Xu, Xiang Chen
Publikováno v:
Chinese medical journal.
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Mitochondrial dysfunction is involved in the pathology of PD. Coiled-coil-helix-coiled-coil-helix domain-containing 2 (CHCHD2) was identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f9648eb8ed7f121d35382ae63cf2db
https://pubmed.ncbi.nlm.nih.gov/35830185
https://pubmed.ncbi.nlm.nih.gov/35830185
Publikováno v:
Biological chemistryReferences. 403(3)
It is widely accepted dietary fiber intimately linked to inflammatory and nervous diseases, which often been described with altered gastrointestinal (GI) motility. However, how dose dietary fiber modulate inflammation and crosstalk influence GI funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b60b1321aac038573102a196cb6a80e
https://pubmed.ncbi.nlm.nih.gov/34536342
https://pubmed.ncbi.nlm.nih.gov/34536342