Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hengameh Shams"'
Autor:
Qin Ma, Hengameh Shams, Alessandro Didonna, Sergio E. Baranzini, Bruce A. C. Cree, Stephen L. Hauser, Roland G. Henry, Jorge R. Oksenberg
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
The combined analysis of single cell and bulk epigenetic datasets and multiple sclerosis GWAS reveals the enrichment of genetic susceptibility signals in B cells and monocyte-microglia cell types.
Externí odkaz:
https://doaj.org/article/675d0cabbd474edfbffe9c5abc5657bf
Autor:
Leonardo M. Amorim, Danillo G. Augusto, Neda Nemat-Gorgani, Gonzalo Montero-Martin, Wesley M. Marin, Hengameh Shams, Ravi Dandekar, Stacy Caillier, Peter Parham, Marcelo A. Fernández-Viña, Jorge R. Oksenberg, Paul J. Norman, Jill A. Hollenbach
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis. We undertook the most comprehensive study to date of KIR geneti
Externí odkaz:
https://doaj.org/article/aa5a1107c343415581b1d8b8a30fec56
Autor:
Mohammad F. Islam, Kris Noel Dahl, Gustavo K. Rohde, Mohammad R. K. Mofrad, Yu-Li Wang, Brian D. Holt, Hengameh Shams, Travis A. Horst, Saurav Basu, Andrew D. Rape
Publikováno v:
Journal of Functional Biomaterials, Vol 3, Iss 2, Pp 398-417 (2012)
With a range of desirable mechanical and optical properties, single wall carbon nanotubes (SWCNTs) are a promising material for nanobiotechnologies. SWCNTs also have potential as biomaterials for modulation of cellular structures. Previously, we show
Externí odkaz:
https://doaj.org/article/0ce3e48accb24163a50daa1e12fb5172
Autor:
Magi Andorra, Ana Freire, Irati Zubizarreta, Nicole Kerlero de Rosbo, Steffan D. Bos, Melanie Rinas, Einar A. Høgestøl, Sigrid A. Rodez Benavent, Tone Berge, Synne Brune-Ingebretse, Federico Ivaldi, Maria Cellerino, Matteo Pardini, Gemma Vila, Irene Pulido-Valdeolivas, Elena H. Martinez-Lapiscina, Sara Llufriu, Albert Saiz, Yolanda Blanco, Eloy Martinez-Heras, Elisabeth Solana, Priscilla Bäcker-Koduah, Janina Behrens, Joseph Kuchling, Susanna Asseyer, Michael Scheel, Claudia Chien, Hanna Zimmermann, Seyedamirhosein Motamedi, Joseph Kauer-Bonin, Alex Brandt, Julio Saez-Rodriguez, Leonidas Alexopoulos, Friedemann Paul, Hanne F Harbo, Hengameh Shams, Jorge Oksenberg, Antonio Uccelli, Ricardo Baeza-Yates, Pablo Villoslada
Background Multiple Sclerosis patients would benefit from machine learning algorithms that integrates clinical, imaging, and multimodal biomarkers to define the risk of disease activity. Methods We have analyzed a prospective multi-centric cohort of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c55f9351aa41992f5d702acbff86d86
https://doi.org/10.21203/rs.3.rs-2414345/v1
https://doi.org/10.21203/rs.3.rs-2414345/v1
Autor:
Hengameh Shams, Jill A. Hollenbach, Atsuko Matsunaga, Mohammad R.K. Mofrad, Jorge R. Oksenberg, Alessandro Didonna
Publikováno v:
Arch Biochem Biophys
The human leukocyte antigen (HLA) locus encodes a large group of proteins governing adaptive and innate immune responses. Among them, HLA class II proteins form α/β heterodimers on the membrane of professional antigen-presenting cells (APCs), where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e981f2d5d6ab0f143a9fd0f7b5530
https://escholarship.org/uc/item/6c79587v
https://escholarship.org/uc/item/6c79587v
Autor:
Atsuko Matsunaga, Stephen L. Hauser, Brenda Ho, Qiumin Tan, Ester Canto Puig, Jorge R. Oksenberg, Stacy J. Caillier, Alessandro Didonna, Hengameh Shams, Nicholas A. Lee, Scott S. Zamvil, Qin Ma
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 38
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Over 200 genomic loci have been found associated with the risk of developing multiple sclerosis (MS). Despite this important body of data, limited information exists on the cellular pathways and molecular mechanisms underlying MS genetic
Autor:
Peter Parham, Mohammad R. K. Mofrad, Paul Norman, Neda Nemat-Gorgani, Wesley M. Marin, Tasneem Yusufali, Ravi Dandekar, Jill A. Hollenbach, Stacy J. Caillier, Marcelo Fernandez-Vina, Danillo G. Augusto, Kirsten M. Anderson, Hengameh Shams, Lisa E. Creary, Chao Zhao, Jorge R. Oksenberg, Gonzalo Montero-Martín
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 205, iss 5
J Immunol
J Immunol
Immune dysfunction plays a role in the development of Parkinson disease (PD). NK cells regulate immune functions and are modulated by killer cell immunoglobulin-like receptors (KIR). KIR are expressed on the surface of NK cells and interact with HLA
Autor:
Andreas R. Bausch, Andrew R. Harris, Pamela Jreij, Kathy Y. Wei, Brian Belardi, Hengameh Shams, Daniel A. Fletcher
Publikováno v:
Molecular biology of the cell, vol 30, iss 26
Molecular Biology of the Cell
Molecular Biology of the Cell
Tandem calponin homology domains are common actin-binding motifs found in proteins such as α-actinin, filamin, utrophin, and dystrophin that organize actin filaments into functional structures. Despite a conserved structural fold and regions of high
Autor:
Marcelo Fernandez-Vina, Leonardo Maldaner Amorim, Danillo G. Augusto, Wesley M. Marin, Ravi Dandekar, Jorge R. Oksenberg, Stacy J. Caillier, Gonzalo Montero-Martín, Paul Norman, Neda Nemat-Gorgani, Hengameh Shams, Peter Parham, Jill A. Hollenbach
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis. We undertook the most comprehensive study to date of KIR geneti
Autor:
Hengameh Shams, Mohammad Soheilypour, Ruhollah Moussavi-Baygi, Mohaddeseh Peyro, Mohammad R. K. Mofrad
Publikováno v:
ACS biomaterials science & engineering, vol 3, iss 11
Shams, H; Soheilypour, M; Peyro, M; Moussavi-Baygi, R; & Mofrad, MRK. (2017). Looking "under the Hood" of Cellular Mechanotransduction with Computational Tools: A Systems Biomechanics Approach across Multiple Scales. ACS Biomaterials Science and Engineering, 3(11), 2712-2726. doi: 10.1021/acsbiomaterials.7b00117. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2xc1d946
Shams, H; Soheilypour, M; Peyro, M; Moussavi-Baygi, R; & Mofrad, MRK. (2017). Looking "under the Hood" of Cellular Mechanotransduction with Computational Tools: A Systems Biomechanics Approach across Multiple Scales. ACS Biomaterials Science and Engineering, 3(11), 2712-2726. doi: 10.1021/acsbiomaterials.7b00117. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2xc1d946
© 2017 American Chemical Society. Signal modulation has been developed in living cells throughout evolution to promote utilizing the same machinery for multiple cellular functions. Chemical and mechanical modules of signal transmission and transduct