Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Heng-Shan Wang"'
Autor:
Rachael M. Curtis, Heng-Shan Wang, Xuan Luo, Erika B. Dugo, Jacqueline J. Stevens, Paul B. Tchounwou
Publikováno v:
Nutrients, Vol 16, Iss 16, p 2737 (2024)
Previous in vitro studies in our laboratory demonstrated that ethyl acetate (P2) and water- soluble (PS/PT1) fractionated leaf extracts of Ocimum gratissimum inhibit the proliferation of prostate cancer cells. It has been reported that the crude aque
Externí odkaz:
https://doaj.org/article/08f1419795b54e81acd2d66a7281d31e
Autor:
Feng Qin, Zi-Shuo Song, Li Luo, Xiang-Long Bo, Fu-Rong Wu, Mei-Jing Tan, Fan-Fan Wang, Xi-Shan Huang, Heng-Shan Wang
Publikováno v:
Marine Drugs, Vol 22, Iss 2, p 58 (2024)
Five new diisoprenyl cyclohexene-type meroterpenoids, aspergienynes J–N (1–5), along with three known analogues (6–8), were obtained from the mangrove endophytic fungal strain Aspergillus sp. GXNU-Y85. The chemical structures, including their a
Externí odkaz:
https://doaj.org/article/e942971e9fd94eb3ae5cf9145b391d0b
Autor:
Yu-Chen Liu, Gang Wei, Zhi-Qiang Liao, Fang-Xin Wang, Chunxiao Zong, Jiannan Qiu, Yifei Le, Zhi-Ling Yu, Seo Young Yang, Heng-Shan Wang, Xiao-Bing Dou, Cai-Yi Wang
Publikováno v:
Molecules, Vol 29, Iss 1, p 12 (2023)
Peroxisome proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1 (CPT1) are important targets of lipid metabolism regulation for nonalcoholic fatty liver disease (NAFLD) therapy. In the present study, a set of novel indo
Externí odkaz:
https://doaj.org/article/14a1bfb236564b499b727a3e68219cf4
Autor:
Ri-Zhen Huang, Qiao-Ling Liang, Xiao-Teng Jing, Ke Wang, Hui-Yong Zhang, Heng-Shan Wang, Xian-Li Ma, Jian-Hua Wei, Ye Zhang
Publikováno v:
Molecules, Vol 28, Iss 16, p 6135 (2023)
Indoleamine-2,3-dioxygenase 1 (IDO1) and signal transducer and activator of transcription 3 (STAT3) have emerged as significant targets in the tumor microenvironment for cancer therapy. In this study, we synthesized three novel 2-amino-1,4-naphthoqui
Externí odkaz:
https://doaj.org/article/bcd5ed2b15b944439553e3d6189e063f
Autor:
Cai Yi Wang, Sunggun Lee, Hyun-Jae Jang, Xiang Dong Su, Heng-Shan Wang, Young Ho Kim, Seo Young Yang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 753-760 (2019)
The aerial parts of Tetrastigma hemsleyanum (APTH) have been used as a functional tea in China. The purpose of the current study was to identify the bioactive constituents with inhibitory activity against soluble epoxide hydrolase (sEH) and inducible
Externí odkaz:
https://doaj.org/article/371454eb299f4b12866c243dd36d3bb4
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100220- (2021)
A rapid and efficient NFSI-mediated hydroxy or alkoxy-selenation of internal alkenes and chalcones is presented. This reaction proceeds smoothly at room temperature and features broad substrate scope, which employs NFSI as the oxidizing agent, afford
Externí odkaz:
https://doaj.org/article/38d48058f94749d1b0e95d1e5dd8eabc
Publikováno v:
ACS Omega, Vol 2, Iss 5, Pp 2178-2183 (2017)
Externí odkaz:
https://doaj.org/article/77706e647b7e46f8a06da9fe50f4906a
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 14791-14809 (2015)
A series of novel coumarin-containing α-aminophosphonates were synthesized and evaluated for their antitumor activities against Human colorectal (HCT-116), human nasopharyngeal carcinoma (human KB) and human lung adenocarcinoma (MGC-803) cell lines
Externí odkaz:
https://doaj.org/article/fcaa7de4cd2f41638658b69522459dea
Autor:
Le Jin, Hong-En Qu, Xiao-Chao Huang, Ying-Ming Pan, Dong Liang, Zhen-Feng Chen, Heng-Shan Wang, Ye Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 14571-14593 (2015)
A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as potent antitumor agents. The in vitro pharmacological screening results revealed that the target compounds exhibited potent cytotoxicity against HeLa, S
Externí odkaz:
https://doaj.org/article/6f7a8aa1dacb4f908c33b5110262e7d1
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 5, Pp 9424-9439 (2013)
Several rhein-phosphonate derivatives (5a–c) were synthesized and evaluated for in vitro cytotoxicity against HepG-2, CNE, Spca-2, Hela and Hct-116 cell lines. Some compounds showed relatively high cytotoxicity. Especially compounds 5b exhibited th
Externí odkaz:
https://doaj.org/article/201dfdc5f25640e492e9ea5c6c0be135