Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Heng-Shan Wang"'
Autor:
Yi-Yu Lin, Yan Lu, Chun-Yun Li, Xue-Fei Ma, Miao-Qing Shao, Yu-Hao Gao, Yu-Qing Zhang, Hai-Ning Jiang, Yan Liu, Yang Yang, Li-Dong Huang, Peng Cao, Heng-Shan Wang, Jin Wang, Ye Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract P2X receptors, a subfamily of ligand-gated ion channels activated by extracellular ATP, are implicated in various physiopathological processes, including inflammation, pain perception, and immune and respiratory regulations. Structural deter
Externí odkaz:
https://doaj.org/article/33216308078841e4a8af9a0b99b62cc9
Autor:
Feng Qin, Zi-Shuo Song, Li Luo, Xiang-Long Bo, Fu-Rong Wu, Mei-Jing Tan, Fan-Fan Wang, Xi-Shan Huang, Heng-Shan Wang
Publikováno v:
Marine Drugs, Vol 22, Iss 2, p 58 (2024)
Five new diisoprenyl cyclohexene-type meroterpenoids, aspergienynes J–N (1–5), along with three known analogues (6–8), were obtained from the mangrove endophytic fungal strain Aspergillus sp. GXNU-Y85. The chemical structures, including their a
Externí odkaz:
https://doaj.org/article/e942971e9fd94eb3ae5cf9145b391d0b
Autor:
Yu-Chen Liu, Gang Wei, Zhi-Qiang Liao, Fang-Xin Wang, Chunxiao Zong, Jiannan Qiu, Yifei Le, Zhi-Ling Yu, Seo Young Yang, Heng-Shan Wang, Xiao-Bing Dou, Cai-Yi Wang
Publikováno v:
Molecules, Vol 29, Iss 1, p 12 (2023)
Peroxisome proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1 (CPT1) are important targets of lipid metabolism regulation for nonalcoholic fatty liver disease (NAFLD) therapy. In the present study, a set of novel indo
Externí odkaz:
https://doaj.org/article/14a1bfb236564b499b727a3e68219cf4
Autor:
Ri-Zhen Huang, Qiao-Ling Liang, Xiao-Teng Jing, Ke Wang, Hui-Yong Zhang, Heng-Shan Wang, Xian-Li Ma, Jian-Hua Wei, Ye Zhang
Publikováno v:
Molecules, Vol 28, Iss 16, p 6135 (2023)
Indoleamine-2,3-dioxygenase 1 (IDO1) and signal transducer and activator of transcription 3 (STAT3) have emerged as significant targets in the tumor microenvironment for cancer therapy. In this study, we synthesized three novel 2-amino-1,4-naphthoqui
Externí odkaz:
https://doaj.org/article/bcd5ed2b15b944439553e3d6189e063f
Autor:
Cai Yi Wang, Sunggun Lee, Hyun-Jae Jang, Xiang Dong Su, Heng-Shan Wang, Young Ho Kim, Seo Young Yang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 753-760 (2019)
The aerial parts of Tetrastigma hemsleyanum (APTH) have been used as a functional tea in China. The purpose of the current study was to identify the bioactive constituents with inhibitory activity against soluble epoxide hydrolase (sEH) and inducible
Externí odkaz:
https://doaj.org/article/371454eb299f4b12866c243dd36d3bb4
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100220- (2021)
A rapid and efficient NFSI-mediated hydroxy or alkoxy-selenation of internal alkenes and chalcones is presented. This reaction proceeds smoothly at room temperature and features broad substrate scope, which employs NFSI as the oxidizing agent, afford
Externí odkaz:
https://doaj.org/article/38d48058f94749d1b0e95d1e5dd8eabc
Publikováno v:
ACS Omega, Vol 2, Iss 5, Pp 2178-2183 (2017)
Externí odkaz:
https://doaj.org/article/77706e647b7e46f8a06da9fe50f4906a
Publikováno v:
Molecules, Vol 20, Iss 8, Pp 14791-14809 (2015)
A series of novel coumarin-containing α-aminophosphonates were synthesized and evaluated for their antitumor activities against Human colorectal (HCT-116), human nasopharyngeal carcinoma (human KB) and human lung adenocarcinoma (MGC-803) cell lines
Externí odkaz:
https://doaj.org/article/fcaa7de4cd2f41638658b69522459dea
Publikováno v:
ARKIVOC, Vol 2013, Iss 3, Pp 49-60 (2013)
Externí odkaz:
https://doaj.org/article/2f4d064ce7d64fecbed0eebe8e494f54
Publikováno v:
Molecules, Vol 16, Iss 1, Pp 100-106 (2010)
A dehydroabietyl derivative 2 bearing a 2-(2′-hydroxyphenyl)benzimidazole unit was synthesized and its sensing behaviors toward metal ions were investigated by UV-Vis and fluorescence spectroscopy methods. In THF solution, compound 2 exhibited exce
Externí odkaz:
https://doaj.org/article/66eb58b7fffd4e20bbb99f49847a72fb