Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heng-Kuan Wong"'
Autor:
José Serrano, Michael D. Southall, Heng-Kuan Wong, Wen-Hwa Li, Manpreet Randhawa, Simarna Kaur, Ramine Parsa
Publikováno v:
Archives of Dermatological Research. 309:275-283
Skin Aging manifests primarily with wrinkles, dyspigmentations, texture changes, and loss of elasticity. During the skin aging process, there is a loss of moisture and elasticity in skin resulting in loss of firmness finally leading to skin sagging.
Autor:
Duckney, Patrick1 patrick.duckney@durham.ac.uk, Heng Kuan Wong2 HWONG4@its.jnj.com, Serrano, José2 jserran4@its.jnj.com, Yaradou, Diaraf2 DYARADOU@its.jnj.com, Oddos, Thierry2 toddos@its.jnj.com, Stamatas, Georgios N.3 GStamata@its.jnj.com
Publikováno v:
BMC Research Notes. 2013, Vol. 6 Issue 1, p1-18. 18p. 3 Charts, 3 Graphs.
Autor:
Heng-Kuan Wong, Françoise Dantzer, Valérie Schreiber, Aurélia Noll, Bernardo Reina-San-Martin, José Yélamos, Léa Gaudot, Isabelle Robert
Publikováno v:
Eur J Immunol
Eur J Immunol, 2017, 47 (4), pp.665-676. ⟨10.1002/eji.201646757⟩
Eur J Immunol, 2017, 47 (4), pp.665-676. ⟨10.1002/eji.201646757⟩
To mount highly specific and adapted immune responses, B lymphocytes assemble and diversify their antibody repertoire through mechanisms involving the formation of programmed DNA damage. Immunoglobulin class switch recombination (CSR) is triggered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3a2de51cecef0a8af35091ee7c1401
https://hal.archives-ouvertes.fr/hal-02369971
https://hal.archives-ouvertes.fr/hal-02369971
Autor:
Balz Frei, Michael D. Southall, Thierry Oddos, Heng-Kuan Wong, Karien J. Rodriguez, Simarna Kaur
Publikováno v:
Journal of Dermatological Science. 72:304-310
Background Environmental factors such as solar ultraviolet (UV) radiation and other external aggressors provide an oxidative challenge that is detrimental to skin health. The levels of endogenous antioxidants decrease with age, thus resulting in less
Publikováno v:
Advances in DNA Repair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed384e37c6447af0015f6e51e80adf2
http://www.intechopen.com/articles/show/title/paulownia-tomentosa-princess-tree-extract-reduces-dna-damage-and-induces-dna-repair-processes-in-ski
http://www.intechopen.com/articles/show/title/paulownia-tomentosa-princess-tree-extract-reduces-dna-damage-and-induces-dna-repair-processes-in-ski
Publikováno v:
EMBO reports
Poly(ADP‐ribosyl)ation is a post‐translational modification of proteins that is mediated by poly(ADP‐ribose) polymerases (PARPs). Although the existence and nature of the nucleic acid‐like molecule poly(ADP‐ribose) (PAR) has been known for
Autor:
David M. Wilson, Salustra S. Urbin, Paul F. Wilson, Heng Kuan Wong, Jinshui Fan, Larry H. Thompson
Publikováno v:
Environmental and Molecular Mutagenesis. 48:491-500
Previous studies using rodent cells indicate that a deficiency in XRCC1 results in reduced single-strand break repair, increased sensitivity to DNA-damaging agents, and elevated levels of sister chromatid exchange (SCE). Epidemiological studies have
Publikováno v:
Molecular Carcinogenesis. 46:91-99
Lead is a widespread environmental toxin, found in contaminated water sources, household paints, and certain occupational settings. Classified as a probable carcinogen by the International Agency for Research on Cancer (IARC), lead promotes mutagenes
Autor:
Meltem Muftuoglu, Patricia L. Opresko, Syed Z. Imam, Vilhelm A. Bohr, David M. Wilson, Heng Kuan Wong
Publikováno v:
Cancer Research. 66:113-124
The ends of linear chromosomes are capped and protected by protein-DNA complexes termed telomeres. Consequences of telomere dysfunction include genomic instability that can contribute to neoplastic transformation and progression. Telomere binding pro
Publikováno v:
Biochemistry. 44:14335-14343
Base excision repair (BER) is the major corrective pathway for most spontaneous, oxidative, and alkylation DNA base and sugar damage. X-ray cross-complementing 1 (XRCC1) has been suggested to function at nearly every step of this repair process, prim