Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Heng Tai Liew"'
Autor:
Side Hu, Seetharamsing Balamkundu, James P. Tam, Heng Tai Liew, Janet To, Xiaohong Zhang, Julien Lescar, Chuan-Fa Liu, Surajit Bhattacharjya, Ning-Yu Chan, Yiyin Xia
Publikováno v:
Angewandte Chemie. 133:22381-22385
Peptidyl asparaginyl ligases (PALs) are powerful tools for peptide macrocyclization. Herein, we report that a derivative of Asn, namely Nγ -hydroxyasparagine or Asn(OH), is an unnatural P1 substrate of PALs. By Asn(OH)-mediated cyclization, we prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6b33c50224dba4f6e15de1b10b312a
https://doi.org/10.1002/ange.202108125
https://doi.org/10.1002/ange.202108125
Autor:
Xinya Hemu, Ning‐Yu Chan, Heng Tai Liew, Side Hu, Xiaohong Zhang, Aida Serra, Julien Lescar, Chuan‐Fa Liu, James P. Tam
Peptide asparaginyl ligases (PALs) are Asn/Asp(Asx)-specific ligases that are useful for precision modifications of proteins and live-cell surfaces. PALs share high sequence and structural similarity to legumains, asparaginyl endopeptidases (AEPs) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2534085a5de724bc7d6e550d09b33d19
https://doi.org/10.1101/2022.09.26.509423
https://doi.org/10.1101/2022.09.26.509423
Autor:
Dingpeng Zhang, Zhen Wang, Side Hu, Ning-Yu Chan, Heng Tai Liew, Julien Lescar, James P. Tam, Chuan-Fa Liu
Publikováno v:
Bioconjugate chemistry. 33(1)
Asparaginyl endopeptidases (AEPs) are cysteinyl enzymes naturally catalyzing the hydrolysis and transpeptidation reactions at Asx-Xaa bonds. These reactions go by a common acyl-enzyme thioester intermediate, which is either attacked by water (for a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5583d6b47df9b4e1a6fd5fbd9804b728
https://pubmed.ncbi.nlm.nih.gov/34985285
https://pubmed.ncbi.nlm.nih.gov/34985285
Autor:
Yiyin, Xia, Janet, To, Ning-Yu, Chan, Side, Hu, Heng Tai, Liew, Seetharamsing, Balamkundu, Xiaohong, Zhang, Julien, Lescar, Surajit, Bhattacharjya, James P, Tam, Chuan-Fa, Liu
Publikováno v:
Angewandte Chemie (International ed. in English). 60(41)
Peptidyl asparaginyl ligases (PALs) are powerful tools for peptide macrocyclization. Herein, we report that a derivative of Asn, namely N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c995c35b64af49d225a65cc4adc3d66c
https://pubmed.ncbi.nlm.nih.gov/34396662
https://pubmed.ncbi.nlm.nih.gov/34396662
Making peptide bonds is tightly controlled by genetic code and machinery which includes cofactors, ATP, and RNAs. In this regard, the stand-alone and genetic-code-independent peptide ligases constitute a new family of renegade peptide-bond makers. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd6d302801657fd5a02e4bff44b8e21
https://hdl.handle.net/10356/148282
https://hdl.handle.net/10356/148282
Autor:
Aida Serra, James P. Tam, Chuan-Fa Liu, Heng Tai Liew, Xinya Hemu, Xiaohong Zhang, Siu Kwan Sze, Janet To, Ning-Yu Chan
Publikováno v:
The Journal of Biological Chemistry
Legumains, also known as asparaginyl endopeptidases (AEPs), cleave peptide bonds after Asn/Asp (Asx) residues. In plants, certain legumains also have ligase activity that catalyzes biosynthesis of Asx-containing cyclic peptides. An example is the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c9fb90642791a2161e47c088998917
https://doi.org/10.1016/j.jbc.2021.101325
https://doi.org/10.1016/j.jbc.2021.101325
Autor:
Heng Tai Liew1, To, Janet1, Xiaohong Zhang1, Xinya Hemu1, Ning-Yu Chan1, Serra, Aida2,3, Siu Kwan Sze1, Chuan-fa Liu1, Tam, James P.1 jptam@ntu.edu.sg
Publikováno v:
Journal of Biological Chemistry. Dec2021, Vol. 297 Issue 6, p1-13. 13p.
Autor:
Hon Lun Wong, Brendan P. Burns, Luděk Sehnal, Brett A. Neilan, Jason N. Woodhouse, Heng Tai Liew, Russel Pickford, Paul M. D'Agostino
Publikováno v:
Environmental microbiology. 21(2)
Shark Bay, Western Australia is a World Heritage area with extensive microbial mats and stromatolites. Microbial communities that comprise these mats have developed a range of mitigation strategies against changing levels of photosynthetically active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d02123e0df31e1328d0647918e5ebed
https://pubmed.ncbi.nlm.nih.gov/30589201
https://pubmed.ncbi.nlm.nih.gov/30589201
Autor:
Xia, Yiyin1 (AUTHOR), To, Janet1 (AUTHOR), Chan, Ning‐Yu1 (AUTHOR), Hu, Side1 (AUTHOR), Liew, Heng Tai1 (AUTHOR), Balamkundu, Seetharamsing1,2 (AUTHOR), Zhang, Xiaohong1 (AUTHOR), Lescar, Julien1 (AUTHOR), Bhattacharjya, Surajit1 (AUTHOR), Tam, James P.1 (AUTHOR) jptam@ntu.edu.sg, Liu, Chuan‐Fa1 (AUTHOR) cfliu@ntu.edu.sg
Publikováno v:
Angewandte Chemie. 10/4/2021, Vol. 133 Issue 41, p22381-22385. 5p.
Autor:
Hemu, Xinya, Chan, Ning‐Yu, Liew, Heng Tai, Hu, Side, Zhang, Xiaohong, Serra, Aida, Lescar, Julien, Liu, Chuan‐Fa, Tam, James P.
Publikováno v:
New Phytologist; May2023, Vol. 238 Issue 4, p1534-1545, 12p