Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology.

Autor: Ewart L; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA. lorna.ewart@emulatebio.com., Apostolou A; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Briggs SA; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Carman CV; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Chaff JT; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Heng AR; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Jadalannagari S; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Janardhanan J; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Jang KJ; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Joshipura SR; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Kadam MM; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Kanellias M; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Kujala VJ; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Kulkarni G; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Le CY; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Lucchesi C; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Manatakis DV; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Maniar KK; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Quinn ME; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Ravan JS; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Rizos AC; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Sauld JFK; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Sliz JD; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Tien-Street W; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Trinidad DR; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Velez J; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Wendell M; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA., Irrechukwu O; Janssen Pharmaceuticals, Spring House, Philadelphia, PA, USA., Mahalingaiah PK; Investigative Toxicology and Pathology, Abbvie, North Chicago, IL, USA., Ingber DE; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Vascular Biology Program and Department of Surgery, Harvard Medical School and Boston Children's Hospital, Boston, MA, USA., Scannell JW; JW Scannell Analytics LTD, 32 Queens Crescent, Edinburgh, EH9 2BA, UK., Levner D; Emulate Inc., 27 Drydock Avenue, Boston, MA, USA.

Publikováno v: Communications medicine [Commun Med (Lond)] 2023 Feb 02; Vol. 3 (1), pp. 16. Date of Electronic Publication: 2023 Feb 02.

An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif.

Autor: Balasubramaniam D; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Schroeder O; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Russell AM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Fitchett JR; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Austin AK; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Beyer TP; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Chen YQ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Day JW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Ehsani M; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Heng AR; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Zhen EY; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Davies J; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Glaesner W; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Jones BE; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Siegel RW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Qian YW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA., Konrad RJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA. Electronic address: konrad_robert@lilly.com.

Publikováno v: Journal of lipid research [J Lipid Res] 2022 May; Vol. 63 (5), pp. 100198. Date of Electronic Publication: 2022 Mar 17.

Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.

Autor: Froning K; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Maguire J; Program in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Sereno A; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Huang F; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Chang S; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Weichert K; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Frommelt AJ; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Dong J; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Wu X; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Austin H; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Conner EM; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Fitchett JR; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Heng AR; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Balasubramaniam D; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Hilgers MT; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA., Kuhlman B; Department of Biochemistry and Biophysics and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. bkuhlman@email.unc.edu., Demarest SJ; Eli Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, CA, 92121, USA. demarestsj@lilly.com.

Publikováno v: Nature communications [Nat Commun] 2020 May 11; Vol. 11 (1), pp. 2330. Date of Electronic Publication: 2020 May 11.

Nuovi Approcci Metodologici: verso una ricerca biomedica scientificamente valida ed eticamente sostenibile.

Autor: CASSOTTA, MANUELA¹ manuela.cassotta@oltrelasperimentazioneanimale.eu

Publikováno v: Il Cesalpino. ott2023, Issue 59, p52-55. 4p.

Accurate prediction of CDR-H3 loop structures of antibodies with deep learning.

Autor: Hedi Chen, Xiaoyu Fan, Shuqian Zhu, Yuchan Pei, Xiaochun Zhang, Xiaonan Zhang, Lihang Liu, Feng Qian, Boxue Tian

Publikováno v: eLife; 6/26/2024, p1-27, 27p