A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer.

Autor: Mason M; Bristol Myers Squibb, Princeton, NJ, USA., Lapuente-Santana Ó; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands., Halkola AS; Department of Mathematics and Statistics, University of Turku, Turku, Finland., Wang W; Faculty of Medicine, Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland., Mall R; Qatar Computing Research Institute, Hamad Bin Khalifa University, P.O. Box 34110, Doha, Qatar.; Department of Immunology, St. Jude Children's Research Hospital, P.O. Box 38105, Memphis, TN, USA.; Biotechnology Research Center, Technology Innovation Institute, P.O. Box 9639, Abu Dhabi, United Arab Emirates., Xiao X; School of Informatics, Xiamen University, Xiamen, China.; National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen, China., Kaufman J; Department of Medicine, Duke University, Durham, NC, USA.; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Fu J; Dana-Farber Cancer Institute, Boston, MA, USA., Pfeil J; AbbVie, South San Francisco, CA, USA., Banerjee J; Sage Bionetworks, Seattle, WA, USA., Chung V; Sage Bionetworks, Seattle, WA, USA., Chang H; Bristol Myers Squibb, Princeton, NJ, USA., Chasalow SD; Bristol Myers Squibb, Princeton, NJ, USA., Lin HY; Bristol Myers Squibb, Princeton, NJ, USA., Chai R; Sage Bionetworks, Seattle, WA, USA., Yu T; Sage Bionetworks, Seattle, WA, USA., Finotello F; Institute of Molecular Biology, University of Innsbruck, Innsbruck, Austria.; Digital Science Center (DiSC), University of Innsbruck, Innsbruck, Austria., Mirtti T; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland.; iCAN-Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; Department of Biomedical Engineering, School of Medicine, Emory University, Atlanta, GA, USA., Mäyränpää MI; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Bao J; Faculty of Medicine, Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland., Verschuren EW; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland., Ahmed EI; Human Immunology Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar., Ceccarelli M; Department of Electrical Engineering and Information Technology (DIETI), University of Naples 'Federico II', 80125, Naples, Italy.; BIOGEM Institute of Molecular Biology and Genetics, Via Camporeale, Ariano Irpino, Italy., Miller LD; Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA., Monaco G; BIOGEM Institute of Molecular Biology and Genetics, Via Camporeale, Ariano Irpino, Italy., Hendrickx WRL; Human Immunology Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, P.O. Box 26999, Doha, Qatar., Sherif S; Human Immunology Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, P.O. Box 26999, Doha, Qatar., Yang L; Dana-Farber Cancer Institute, Boston, MA, USA., Tang M; Dana-Farber Cancer Institute, Boston, MA, USA., Gu SS; Dana-Farber Cancer Institute, Boston, MA, USA., Zhang W; Dana-Farber Cancer Institute, Boston, MA, USA., Zhang Y; Dana-Farber Cancer Institute, Boston, MA, USA., Zeng Z; Dana-Farber Cancer Institute, Boston, MA, USA., Das Sahu A; Dana-Farber Cancer Institute, Boston, MA, USA., Liu Y; Dana-Farber Cancer Institute, Boston, MA, USA., Yang W; Aginome Scientific, Xiamen, China., Bedognetti D; Human Immunology Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, P.O. Box 26999, Doha, Qatar.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy., Tang J; Faculty of Medicine, Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland.; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Eduati F; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.; Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, Eindhoven, The Netherlands., Laajala TD; Department of Mathematics and Statistics, University of Turku, Turku, Finland.; Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland.; iCAN-Digital Precision Cancer Medicine Flagship, Helsinki, Finland.; FICAN West Cancer Centre, University of Turku and Turku University Hospital, Turku, Finland.; Department of Pharmacology, Anschutz Medical Campus, University of Colorado, Denver, CO, USA., Geese WJ; Bristol Myers Squibb, Princeton, NJ, USA., Guinney J; Tempus Labs, Chicago, IL, USA., Szustakowski JD; Bristol Myers Squibb, Princeton, NJ, USA., Vincent BG; Department of Medicine, Division of Hematology, Department of Microbiology and Immunology, Curriculum in Bioinformatics and Computational Biology, Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Carbone DP; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA. david.p.carbone@gmail.com.

Publikováno v: Journal of translational medicine [J Transl Med] 2024 Feb 21; Vol. 22 (1), pp. 190. Date of Electronic Publication: 2024 Feb 21.

Identification of an unusual combination of actionable mutations through genomic profiling in a child with an aggressive sarcoma.

Autor: Sherif S; Tumor Biology and Immunology Laboratory, Research Branch, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar., Hendrickx WRL; Tumor Biology and Immunology Laboratory, Research Branch, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar., Raynaud CM; Tumor Biology and Immunology Laboratory, Research Branch, Sidra Medicine, Doha, Qatar., Mifsud W; Anatomical Pathology, Sidra Medicine, Doha, Qatar., Bedognetti D; Tumor Biology and Immunology Laboratory, Research Branch, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar., Maaz AUR; Pediatric Hematology and Oncology Division, Sidra Medicine, Doha, Qatar.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Jan; Vol. 71 (1), pp. e30730. Date of Electronic Publication: 2023 Oct 16.

The immune landscape of solid pediatric tumors.

Autor: Sherif S; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar., Roelands J; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar.; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands., Mifsud W; Department of Pathology, Doha, Qatar.; Weill Cornell Medicine-Qatar, Doha, Qatar., Ahmed EI; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar., Raynaud CM; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar., Rinchai D; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar., Sathappan A; Deep phenotyping core, Research Branch, Sidra Medicine, Doha, Qatar., Maaz A; Pediatric Hematology and Oncology Division, Sidra Medicine, Doha, Qatar., Saleh A; Pediatric Hematology and Oncology Division, Sidra Medicine, Doha, Qatar.; Department of Pediatrics, Northeast Ohio Medical University, Rootstown, OH, USA., Ozer E; Department of Pathology, Doha, Qatar.; Institute of Oncology, Dokuz Eylul University, Izmir, Turkey., Fakhro KA; Human Genetics Department, Research Branch, Sidra Medicine, Doha, Qatar.; Department of Genetic Medicine, Weill Cornell Medicine-Qatar, Doha, Qatar., Mifsud B; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; William Harvey Research Institute, Queen Mary University of London, London, UK., Thorsson V; Institute for Systems Biology, 401 Terry Ave N, Seattle, WA, 98109, USA., Bedognetti D; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. dbedognetti@sidra.org.; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar. dbedognetti@sidra.org.; Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy. dbedognetti@sidra.org., Hendrickx WRL; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. whendrickx@sidra.org.; Human Immunology Department, Research Branch, Sidra Medicine, Doha, Qatar. whendrickx@sidra.org.

Publikováno v: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Jun 11; Vol. 41 (1), pp. 199. Date of Electronic Publication: 2022 Jun 11.