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Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.

Autor: Carreno-Florez GP; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America., Kocak BR; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Hendricks MR; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Melvin JA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Mar KB; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Kosanovich J; Department of Pharmacy and Therapeutics and Center for Clinical Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, United States of America., Cumberland RL; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Delgoffe GM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Shiva S; Department of Pharmacology and Chemical Biology and Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Empey KM; Department of Pharmacy and Therapeutics and Center for Clinical Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, United States of America.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Schoggins JW; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Bomberger JM; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2023 Nov 08; Vol. 19 (11), pp. e1011719. Date of Electronic Publication: 2023 Nov 08 (Print Publication: 2023).

Iron bioavailability regulates Pseudomonas aeruginosa interspecies interactions through type VI secretion expression.

Autor: Haas AL; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA., Zemke AC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Melvin JA; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA., Armbruster CR; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA., Hendricks MR; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA., Moore J; Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Nouraie SM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA., Thibodeau PH; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA., Lee SE; Division of Otolaryngology, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Bomberger JM; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA. Electronic address: jbomb@dartmouth.edu.

Publikováno v: Cell reports [Cell Rep] 2023 Mar 28; Vol. 42 (3), pp. 112270. Date of Electronic Publication: 2023 Mar 16.

Extracellular vesicles promote transkingdom nutrient transfer during viral-bacterial co-infection.

Autor: Hendricks MR; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Lane S; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Program in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Melvin JA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Ouyang Y; Magee-Womens Research Institute, Department of OBGYN and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA., Stolz DB; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Williams JV; Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, USA., Sadovsky Y; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA; Magee-Womens Research Institute, Department of OBGYN and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA., Bomberger JM; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA. Electronic address: jbomb@pitt.edu.

Publikováno v: Cell reports [Cell Rep] 2021 Jan 26; Vol. 34 (4), pp. 108672.