Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hend Abdelrasoul"'
Autor:
Adrian Gihring, Fabian Gärtner, Laura Mayer, Aileen Roth, Hend Abdelrasoul, Marko Kornmann, Leonard Elad, Uwe Knippschild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionObesity is associated with low-grade chronic inflammation, altered levels of adipocytokines, and impaired regulation of gastrointestinal hormones. Secreted, these factors exert immunostimulatory functions directly influencing peripheral i
Externí odkaz:
https://doaj.org/article/492ce8d922654dfd87eefb99e512958d
Autor:
Franz Ketzer, Hend Abdelrasoul, Mona Vogel, Ralf Marienfeld, Markus Müschen, Hassan Jumaa, Thomas Wirth, Alexey Ushmorov
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subseq
Externí odkaz:
https://doaj.org/article/cd3fcf0a0bbb43f9a95cf28d3dfc64d4
Autor:
Anila Vadakumchery, Hemin Faraidun, Omar El Ayoubi, Issame Outaleb, Vera Schmid, Hend Abdelrasoul, Timm Amendt, Ahmad Khadour, Corinna Setz, Katharina Göhring, Karoline Lodd, Christoffer Hitzing, Alabbas Alkhatib, Mayas Bilal, Julian Benckendorff, Abdul Kader Al Shugri, Cord Herbert Brakebusch, Niklas Engels, Moumita Datta, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The generation, differentiation, survival and activation of B cells are coordinated by signals emerging from the B cell antigen receptor (BCR) or its precursor, the pre-BCR. The adaptor protein SLP65 (also known as BLNK) is an important signaling fac
Externí odkaz:
https://doaj.org/article/bba221cfcb304def8ce9db2a80eaa6fd
Autor:
Hend Abdelrasoul, Anila Vadakumchery, Markus Werner, Lennart Lenk, Ahmad Khadour, Marc Young, Omar El Ayoubi, Fotini Vogiatzi, Markus Krämer, Vera Schmid, Zhengshan Chen, Yasar Yousafzai, Gunnar Cario, Martin Schrappe, Markus Müschen, Christina Halsey, Medhanie A. Mulaw, Denis M. Schewe, Elias Hobeika, Ameera Alsadeq, Hassan Jumaa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Emergence of ABL1 kinase inhibitor resistant clones may cause disease relapse in Philadelphia chromosome-positive acute lymphoblastic leukemia. Here, the authors show interleukin 7 receptor (IL7R) signaling to contribute to this resistance mechanism,
Externí odkaz:
https://doaj.org/article/a25003f7a49e4b7f9022e8001e0418c9
Autor:
Corinna S. Setz, Eva Hug, Ahmad Khadour, Hend Abdelrasoul, Mayas Bilal, Elias Hobeika, Hassan Jumaa
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 391-405 (2018)
Summary: Activation of phosphoinositide 3-kinase (PI3K) signaling plays a central role in regulating proliferation and survival of B cells. Here, we tested the hypothesis that B cell receptor (BCR)-mediated activation of PI3K induces the terminal dif
Externí odkaz:
https://doaj.org/article/d256a6fca1c248cea26c7e197f6fd9d4
The Role of the MAPK Signaling, Topoisomerase and Dietary Bioactives in Controlling Cancer Incidence
Publikováno v:
Diseases, Vol 5, Iss 2, p 13 (2017)
Reactive oxygen species (ROS) are common products of mitochondrial oxidative phosphorylation, xenobiotics metabolism and are generated in response to several environmental stress conditions. Some of them play important biochemical roles in cellular s
Externí odkaz:
https://doaj.org/article/083d0f7afa55479280e518ddf2d1ca9f
Autor:
Franz Ketzer, Hend Abdelrasoul, Mona Vogel, Ralf Marienfeld, Markus Müschen, Hassan Jumaa, Thomas Wirth, Alexey Ushmorov
Publikováno v:
Oncogenesis
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subsequent depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbdbf0c4da1a691ab482b278c210ca4
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec8eddd12a11301abd99f910d44ba16
The Role of the MAPK Signaling, Topoisomerase and Dietary Bioactives in Controlling Cancer Incidence
Publikováno v:
Diseases
Diseases, Vol 5, Iss 2, p 13 (2017)
Diseases, Vol 5, Iss 2, p 13 (2017)
Reactive oxygen species (ROS) are common products of mitochondrial oxidative phosphorylation, xenobiotics metabolism and are generated in response to several environmental stress conditions. Some of them play important biochemical roles in cellular s