Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hend A. Hekal"'
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-31 (2024)
Abstract Heterocyclic compounds play a crucial role in the drug discovery process and development due to their significant presence and importance. Here, we report a comprehensive analysis of α-aminophosphonates containing pyridine (3a–g), prepare
Externí odkaz:
https://doaj.org/article/10381ea1e6ae42bc9bc280f33d997cc2
Autor:
Mohamed H. Baren, Seham A. Ibrahim, Munirah M. Al-Rooqi, Saleh A. Ahmed, Mohammed M. El-Gamil, Hend A. Hekal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract The present study involves synthesis a new series of α-aminophosphonates 2a-f and 4a-d derivatives in good yield with a simple workup via Kabachnik-Fields reaction in the presence of lithium perchlorate as Lewis acid catalyst. All the newly
Externí odkaz:
https://doaj.org/article/d09950ff858048d2a5ccf34b1d45d1b4
Autor:
Faten M. Atlam, Hend A. Hekal
Publikováno v:
Journal of the Iranian Chemical Society.
Through the Kabachnic-Fields three-component reaction of 3(2-amino-acetyl)-quinazolin-4(3H)-one, compound III, various aromatic aldehydes, triphenyl phosphite, and lithium perchlorate as Lewis acid catalyst, new α-amino phosphonates molecules, IVa-f
Publikováno v:
ChemistrySelect. 8
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 206:78-88
A new diphenyl (aryl) (Ǹ-quinazolin-4-yl-hydrazino) methylphosphonates 3a-3d was synthesized via anhydrous zinc chloride catalyzed Kabachnic-Fields reaction. The structure of the synthesized compounds was confirmed by elemental analysis, FT-IR, 1H N
Publikováno v:
Journal of Molecular Structure. 1173:128-141
Diphenyl (aryl) (4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acid hydrazino methyl phosphonate (IIIa-k) was achieved upon the reaction of 3, 4-dihydro-(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acid hydrazide I with various aromatic aldehydes (IIa-k) ,
Publikováno v:
Current Organic Synthesis. 15:286-296
Aim and Objective: Synthesis of new .-aminophosphonates containing quinazoline moiety through Kabachnik-Fields reaction in the presence of copper triflate catalyst [32], followed by studying their antimicrobial activities and in vitro anticancer acti
Publikováno v:
Delta Journal of Science. 38:194-209
A novel series of Diphenyl (aryl) (4-oxo-quinazolin-4(3H)-ylamino) methyl phosphonates (1-4)isobtained in high yields from the reactions of 3-amino-4(3H)-quinazolinone with different aromatic aldehydesand triphenylphosphite in the presence of cupper