Nuclear factor kappa B activation in cardiomyocytes by serum of children with obstructive sleep apnea syndrome

Autor: Meital Gannot, Aviv Goldbart, Hen Haddad, Jacob Gopas

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

Obstructive sleep apnea syndrome (OSA) is associated with cardiovascular morbidity in adults and children. NFκB activity is enhanced in circulating monocytes of adults with OSA, that decreases following positive pressure therapy. OSA children’s se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7aab8d03501002b7cf4861695d4ab3
https://doaj.org/article/bda5dd0b1c3a41ffa6d9adccf358c4b7

The Effect of Sera from Children with Obstructive Sleep Apnea Syndrome (OSAS) on Human Cardiomyocytes Differentiated from Human Embryonic Stem Cells

Autor: Yoram Etzion, Rivka Ofir, Sharon Etzion, Jacob Gopas, Aviv Goldbart, Danielle Regev, Tatiana Rabinski, Hen Haddad

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11418, p 11418 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21

Obstructive sleep apnea syndrome (OSAS) patients suffer from cardiovascular morbidity, which is the leading cause of death in this disease. Based on our previous work with transformed cell lines and primary rat cardiomyocytes, we determined that upon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb663b67697d7350a2fbbe41ca8bf214
https://doi.org/10.3390/ijms222111418

0027 Alternations in Contractility, Calcium Signaling and Nuclear Factor Kappa B Activation in Stem Cells Derived Cardiomyocytes Following Exposure to Obstructive Sleep Apnea Children’s Serum, and Intermittent Hypoxia

Autor: Sharon Etzion, Aviv Goldbart, Jacob Gopas, Hen Haddad

Publikováno v: Sleep. 43:A11-A11

Introduction There are cardiovascular morbid effects of OSA in adults and children. We have previously reported over-expression of Nuclear-Factor-κappa B in tonsils of children with OSA, and NF-κB activation after exposure to sera of children with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::236bea7f41d0f5b5eaf48a8e62aaa9d6
https://doi.org/10.1093/sleep/zsaa056.026