Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Hen Egg Lysozyme"'
Autor:
Izabela P. Klaska, Tian Yu, Rosie Fordyce, Koju Kamoi, Richard J. Cornall, Cristina Martin-Granados, Lucia Kuffova, John V. Forrester
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Restoration of immunological tolerance to self antigens has been a major drive in understanding the mechanisms of, and developing new treatments for, autoimmune and autoinflammatory disease. Sessile dendritic cells (DC) are considered the main instru
Externí odkaz:
https://doaj.org/article/15a83eb5a4514cd0bdbba1118b7e9ad2
Publikováno v:
Sensors, Vol 23, Iss 4, p 2251 (2023)
Quenchbodies (Q-bodies), a type of biosensor, are antibodies labeled with a fluorescent dye near the antigen recognition site. In the absence of an antigen, the dye is quenched by tryptophans in the antibody sequence; however, in its presence, the dy
Externí odkaz:
https://doaj.org/article/2b2a27eab450482d8d1f0563f7d4d294
Akademický článek
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Autor:
Yi-Hsia Liu, Christine Mölzer, Kimmo Makinen, Koju Kamoi, Clare L. C. Corbett, Izabela P. Klaska, Delyth M. Reid, Heather M. Wilson, Lucia Kuffová, Richard J. Cornall, John V. Forrester
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We specify the clinical features of a spontaneous experimental autoimmune uveitis (EAU) model, in which foreign hen-egg lysozyme (HEL) is expressed in the retina, controlled by the promoter for interphotoreceptor retinol binding protein (IRBP). We pr
Externí odkaz:
https://doaj.org/article/3369c1a46cdd4c748e1c067e9394d08e
Publikováno v:
Autoimmunity, Vol 50, Iss 6, Pp 363-369 (2017)
The underlying cellular and molecular mechanism for the development of Type 1 diabetes is still to be fully revealed. We have previously demonstrated that the NOD mouse, a model for Type 1 diabetes, display a prolonged and enhanced immune response to
Externí odkaz:
https://doaj.org/article/d272106a59924511b83ac030a2b0d8ea
Publikováno v:
The Journal of Biochemistry. 170:623-629
A substantial body of work has been carried out describing the structural features of the complex between single-domain antibodies (VHHs) and antigens, and the preeminence for epitopes located at concave surfaces of the antigen. However, the thermody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e803e739f1fcdeef0e747b57ba69d5
https://doi.org/10.1093/jb/mvab082
https://doi.org/10.1093/jb/mvab082
Autor:
Hee-Jin Jeong, Hiroshi Ueda
Publikováno v:
Sensors, Vol 14, Iss 7, Pp 13285-13297 (2014)
Antibody-based sensors have made outstanding contributions to the fields of molecular biology and biotechnology. Our group recently developed a novel powerful fluorescent immunosensor strategy named Quenchbody (Q-body), which has been applied to the
Externí odkaz:
https://doaj.org/article/c3bf46bbc3e0413f9bfd5b12288e5509
Publikováno v:
Amino Acids. 53:745-751
Taurine is a compatible osmolyte that confers stability to proteins. Recent studies have revealed that liquid–liquid phase separation (LLPS) of proteins underlie the formation of membraneless organelles in cells. In the present study, we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59897c5930953353cbd25b37f1da6e82
https://doi.org/10.1007/s00726-021-02980-2
https://doi.org/10.1007/s00726-021-02980-2
Akademický článek
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Akademický článek
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