Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Heme carrier protein 1"'
Autor:
Steven O. Mansoorabadi, Shuxin Li, Eta A. Isiorho, Chidinma L. Odili, Victoria L. Owens, Patrick H. Donnan
Publikováno v:
The Journal of Biological Chemistry
Heme oxygenases (HOs) play a critical role in recouping iron from the labile heme pool. The acquisition and liberation of heme iron are especially important for the survival of pathogenic bacteria. All characterized HOs, including those belonging to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897d1c96471b401b8ef44458dcca4344
http://europepmc.org/articles/PMC8131568
http://europepmc.org/articles/PMC8131568
Autor:
Maki Niihori, Joel James, Sergey Kurdyukov, Cody A. Eccles, Olga Rafikova, Mathews Valuparampil Varghese, Ruslan Rafikov
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-9 (2020)
Biology of Sex Differences
Biology of Sex Differences
Background The mechanisms involved in pulmonary hypertension (PH) development in patients and pre-clinical models are poorly understood. PH has a well-established sex dimorphism in patients with increased frequency of PH in females, and more severe d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b972b9f8acfbd2b900265aa595fc76
https://doi.org/10.1186/s13293-020-00289-5
https://doi.org/10.1186/s13293-020-00289-5
Autor:
Hiromu Ito
Publikováno v:
Applied Sciences, Vol 11, Iss 3503, p 3503 (2021)
Applied Sciences
Volume 11
Issue 8
Applied Sciences
Volume 11
Issue 8
Photodynamic therapy (PDT) is a minimally invasive cancer therapy that combines the accumulation of photosensitizers such as porphyrins in cancer cells with laser irradiation. I have previously reported that mitochondrially derived reactive oxygen sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba7e9b7a2fad1db91efb6222a9901a1
https://doi.org/10.3390/app11083503
https://doi.org/10.3390/app11083503
Autor:
Hiromu Ito, Hiroko P. Indo, Hirofumi Matsui, Hiromi Kurokawa, Hideyuki J. Majima, Aki Hirayama
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Iron is an essential nutrient for life and is involved in many important processes such as oxygen transport and DNA synthesis. However, excess amounts of iron can cause carcinogenesis by producing reactive oxygen species. Thus, the cellular transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701399db5b52a6c705292e8073474b1e
https://doi.org/10.3164/jcbn.17-8
https://doi.org/10.3164/jcbn.17-8
Autor:
Hiroko P. Indo, Hideyuki J. Majima, Hiromu Ito, Hirofumi Matsui, Ichinosuke Hyodo, Masato Tamura
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Photodynamic therapy using hematoporphyrin and its derivatives is clinically useful for cancer treatments. It has been reported that cancer cells incorporate hematoporphyrin and its derivatives via heme carrier protein 1, which is a proton-coupled fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf5a63e20c785ff59481833590d5ae8
http://europepmc.org/articles/PMC4078070
http://europepmc.org/articles/PMC4078070
Autor:
Xianglin Duan, Yan-Zhong Chang, Peng Yu, Yashuo Zhao, Guofen Gao, Delong Liu, Yan Wang, Lina Geng
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 12:1747-1755
The absorption mechanism of heme iron remains unclear due to the limit of labeling techniques. Quantum dots (QDs) are powerful fluorescent probes resistant to photobleaching, however, there is no data about the application of QDs in heme iron absorpt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b888190e11971d8de9da87d5fd34ba2f
https://doi.org/10.1016/j.nano.2016.04.007
https://doi.org/10.1016/j.nano.2016.04.007
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Iron overload has attracted much attention because of its adverse effect in increasing the risk of developing several neurodegenerative disorders. Under various pathologic conditions, a lot of heme are released. The aggregation of heme is more neurot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc04fda3743b4914f6b46772353d037
http://europepmc.org/articles/PMC5515979
http://europepmc.org/articles/PMC5515979
Autor:
Masahiko Terasaki, Hidemi Shigekawa, Atsushi Taninaka, Daisuke Matano, Hiromi Kurokawa, Hirofumi Matsui, Hiromu Ito
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0222074 (2019)
PLoS ONE, Vol 14, Iss 9, p e0222074 (2019)
Photodynamic therapy (PDT) is a cancer therapy that capitalizes on cancer-specific porphyrin accumulation. We have investigated this phenomenon to propose the following three conclusions: 1) the mechanism underlying this phenomenon is closely related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84054bc3ede84db9bea037c09de6ce0
https://tsukuba.repo.nii.ac.jp/records/2001464
https://tsukuba.repo.nii.ac.jp/records/2001464
Publikováno v:
American Journal of Physiology-Cell Physiology. 304:C1159-C1167
The proton-coupled folate transporter (PCFT, SLC46A1) mediates folate transport across the apical brush-border membrane of the proximal small intestine and the basolateral membrane of choroid plexus ependymal cells. Two loss-of-function mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30051d113b8a1e3ecb62310ef41d1f6c
https://doi.org/10.1152/ajpcell.00353.2012
https://doi.org/10.1152/ajpcell.00353.2012
Autor:
Ikumi Tamai, Masato Tamura, Yumiko Nagano, Junko Tanaka, Tsuyoshi Kaneko, Yoshihiro Miwa, Mariko Hiyama, Takeo Nakanishi, Ichinosuke Hyodo, Kazuhiro Hiyama, Tetsuo Ogawa, Osamu Shimokawa, Hirofumi Matsui
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 17:36-43
Although exogenous porphyrin accumulation in cancer cells is important for the success of photodynamic therapies, the mechanism is not clear. We hypothesized that a newly reported transporter, heme carrier protein 1 (HCP1), is highly expressed in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e664f5309a659d7c426274f5047f037c
https://doi.org/10.1142/s1088424612501192
https://doi.org/10.1142/s1088424612501192