Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Hemchandra K, Chaudhari"'
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100097- (2021)
The one-pot synthesis of 2,2,4-trimethyl-1,2-dihydroquinolines by the reaction of anilines with acetone or desired ketone catalysed by MOF-199 was developed in a mild, convenient, solvent free and efficient reaction procedure. Heterogeneous catalyst,
Externí odkaz:
https://doaj.org/article/47d1d87b7b21447d956c25b00ebe8c73
Publikováno v:
Medicine in Drug Discovery, Vol 2, Iss , Pp - (2019)
The ligand library reporting anticancer activities was taken from literature containing forty-two 4-oxo-1,4-dihydroquinoline-3-carboxamides derivatives and was thoroughly investigated against cancer target (pdb id-5U6B) using docking protocol. In ord
Externí odkaz:
https://doaj.org/article/1b2b250a804446409e0852fbfcc1c86c
Publikováno v:
Infectious Disorders - Drug Targets. 22
Background: The conventional approach for the development of any pharmaceutically active molecule is a time-consuming and costly process because the synthesis is followed by laboratory tests which are then followed by long clinical trials. Hence, a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dff2ed6213a097efd71ce9453e5a16
https://doi.org/10.2174/1871526522666220105113357
https://doi.org/10.2174/1871526522666220105113357
Publikováno v:
Current Computer-Aided Drug Design. 16:802-813
Background: Antimicrobial resistance is a major global health problem, which is being rapidly deteriorating the quality of human health. Series of substituted N-(benzo[d]thiazol-2-yl)-2- (4-(6-fluorobenzo[d]isoxazol-3-yl) piperidin-1-yl)acetamide (3a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db6121a3f98af66b25f514f914440b
https://doi.org/10.2174/1573409915666191210125647
https://doi.org/10.2174/1573409915666191210125647
Autor:
Suraj N. Mali, Rajesh S. Kenny, Bhagwat S. Jadhav, Mustapha Mandewale, Hemchandra K. Chaudhari, Ramesh S. Yamgar
Publikováno v:
Current Computer-Aided Drug Design. 16:511-522
Background: A series of new six thiazolyl-2-amine-based Schiff base derivatives (4a-4f) were synthesized by a sequential multistep reaction starting with Salicylaldehyde. Methods: All the Schiff base derivatives were screened in-vitro for their antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caf64cc3c4f034a344e02ca1c2549c7
https://doi.org/10.2174/1386207322666190722162100
https://doi.org/10.2174/1386207322666190722162100
Autor:
Suraj N. Mali, Devidas G. Anuse, Hemchandra K. Chaudhari, Ramesh S. Yamgar, Sudhir Sawant, Bapu R. Thorat
Publikováno v:
Current Computer-Aided Drug Design. 16:530-540
Background: Benzothiazoles are reported to have bioorganic and pharmaceutical chemistry applications. Introduction: A series of substituted N-bromoamido-2-aminobenzothiazoles was synthesized from substituted anilines via 2-aminobenzothiazoles and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0155c073fea99113ff04138d19dc59b5
https://doi.org/10.2174/1573409915666190902143648
https://doi.org/10.2174/1573409915666190902143648
Present work reports an efficient and environmentally benign approach for the synthesis of isoxazole-5(4H)-ones derivatives using lipase as biocatalyst. The one-pot multicomponent reaction of aldehyde, ethyl acetoacetate, and hydroxylamine hydrochlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cbf1d0c2db8785ceb6348d72273ba3
Publikováno v:
Current Computer-Aided Drug Design. 15:445-455
Background: : Thiadiazole not only acts as “hydrogen binding domain” and “two-electron donor system” but also as constrained pharmacophore. Methods:: The maleate salt of 2-((2-hydroxy-3-((4-morpholino-1, 2,5-thiadiazol-3-yl) oxy) propyl) amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03b2e5fb1a6ec60031dbbcbc5b1845d
https://doi.org/10.2174/1573409915666190206142756
https://doi.org/10.2174/1573409915666190206142756
Publikováno v:
Journal of Heterocyclic Chemistry. 56:3048-3054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e94b41ba3f18821b8b4821a6b6b70d3e
https://doi.org/10.1002/jhet.3700
https://doi.org/10.1002/jhet.3700