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of 4
pro vyhledávání: '"Hemaxi Vasavada"'
Autor:
Michael Hunter, Xiaobing Jiang, Clifford W. Bogue, Christine M. Wilson, Rong Cong, Hemaxi Vasavada
Publikováno v:
Biochemical and Biophysical Research Communications. 346:535-545
Hhex encodes a homeodomain-containing protein that functions as both a transcriptional repressor and activator, and is necessary for normal embryonic development. We previously reported that a null mutation of Hhex leads to abnormalities in vasculoge
Autor:
Clifford W. Bogue, James L. McGrath, Harris C. Jacobs, Emese Pinter, Martina Brueckner, Haifa Hallaq, Josephine Enciso, Hemaxi Vasavada, Xiaobing Jiang, Caroline J. Zeiss, Joseph A. Madri, Christine M. Wilson
Publikováno v:
Development. 131:5197-5209
The homeobox gene Hhex has recently been shown to be essential for normal liver, thyroid and forebrain development. Hhex–/– mice die by mid-gestation (E14.5) and the cause of their early demise remains unclear. Because Hhex is expressed in the de
Autor:
Diane W. Dynia, Ian Gross, Christine M. Wilson, Clifford W. Bogue, Hemaxi Vasavada, Harris C. Jacobs
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 266:L448-L454
Hox genes are sequence-specific DNA transcription factors, which are important in embryonic development and are expressed in a number of fetal tissues, including the lung. Additionally, retinoic acid (RA) has been shown to modulate Hox gene expressio
Autor:
Clifford W. Bogue, Christine M. Wilson, Xiaobing Jiang, Klaus H. Kaestner, Michael Hunter, Hemaxi Vasavada, Rong Cong
Publikováno v:
Developmental biology. 308(2)
Hhex is required for early development of the liver. A null mutation of Hhex results in a failure to form the liver bud and embryonic lethality. Therefore, Hhex null mice are not informative as to whether this gene is required during later stages of