Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hematopoietic Protein Tyrosine Phosphatase"'
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12206, p 12206 (2021)
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12206, p 12206 (2021)
Volume 22
Issue 22
The kinase interaction motif protein tyrosine phosphatases (KIM-PTPs), HePTP, PTPSL and STEP, are involved in the negative regulation of mitogen-activated protein kinase (MAPK) signalling pathways and are important therapeutic targets for a number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb4c34e3ce82620a083009a13f05df8
https://pubmed.ncbi.nlm.nih.gov/34830087
https://pubmed.ncbi.nlm.nih.gov/34830087
Akademický článek
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Publikováno v:
Biomolecular NMR Assignments. 12:5-9
The sequence-specific backbone assignment of HePTP (hematopoietic protein tyrosine phosphatase; PTPN7) in presence of vanadate have been determined, based on triple-resonance experiments using uniformly [(13)C,(15)N]-labeled protein. These assignment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04880a1b95129d37144463c0bcabb440
https://doi.org/10.1007/s12104-017-9770-7
https://doi.org/10.1007/s12104-017-9770-7
Autor:
Xochella Chan, Eduard Sergienko, David A Critton, Ekaterina V. Bobkova, Nicholas D. P. Cosford, Li Yang, Rebecca Page, Paul J. Lombroso, Brock Brown, Shyama Sidique, Justin Rascon, Stefan Vasile, Ying Su, Thomas D.Y. Chung, Russell Dahl, Tomas Mustelin, Hongbin Yuan, Sharon Colayco, Wallace Liu, Lutz Tautz, Jian Xu
Publikováno v:
ACS Chemical Biology. 7:367-377
The hematopoietic protein tyrosine phosphatase (HePTP) is implicated in the development of blood cancers through its ability to negatively regulate the mitogen-activated protein kinases (MAPKs) ERK1/2 and p38. Small-molecule modulators of HePTP activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a0a8233e260ab3586098511742b7ce
https://doi.org/10.1021/cb2004274
https://doi.org/10.1021/cb2004274
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2953-2958
Cinnamic acid derivatives were prepared on Rink resin using tert -butyl-4-carboxycinnamate in a four-component Ugi condensation. Inhibition of the hematopoietic protein tyrosine phosphatase (HePTP) by these small molecules is reported. An IC 50 value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb77721d22d7fcace6cdeb735c3476d5
https://doi.org/10.1016/0960-894x(95)00533-6
https://doi.org/10.1016/0960-894x(95)00533-6
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 64:C317-C318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7222aea66e57225e95e74b295763c175
https://doi.org/10.1107/s0108767308089848
https://doi.org/10.1107/s0108767308089848
Akademický článek
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