Zobrazeno 1 - 10 of 1 381 pro vyhledávání: '"Hematologic cancers and related disorders"'
1
Proteome changes of plasma-derived extracellular vesicles in patients with myelodysplastic syndrome
Autor: Klara Pecankova, Pavla Pecherkova, Zdenka Gasova, Zofie Sovova, Tomas Riedel, Eliézer Jäger, Jaroslav Cermak, Pavel Majek
Publikováno v: PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262484 (2022)
PLoS ONE
BackgroundExtracellular vesicles are released into body fluids from the majority of, if not all, cell types. Because their secretion and specific cargo (e.g., proteins) varies according to pathology, extracellular vesicles may prove a rich source of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b004d6c7ccd12ecad6b3e493e6db8d9c
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746746/?tool=EBI
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2
A prospective registry-based cohort study of the diagnosis and management of acute leukaemia in pregnancy: Study protocol
Autor: Matthew Northgraves, David Allsup, Judith Cohen, Chao Huang, John Turgoose, Sahra Ali
Publikováno v: PLoS ONE, Vol 17, Iss 2, p e0263195 (2022)
PLoS ONE
Background Acute leukaemias (AL) are aggressive but potentially curable blood cancers that can potentially affect women of childbearing age. When a pregnancy is complicated by a diagnosis of AL, clinicians face a complex dilemma: to balance risking t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320401096f0da9e16462d200dcb11b58
https://doaj.org/article/ad2b956c62104d7294a973eebb9509dc
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3
A novel pro-oxidant combination of resveratrol and copper reduces transplant related toxicities in patients receiving high dose melphalan for multiple myeloma (RESCU 001)
Autor: Anshul Agarwal, Aakanksha Khandelwal, Kavita Pal, Naveen Kumar Khare, Vishal Jadhav, Murarilal Gurjar, Sachin Punatar, Anant Gokarn, Avinash Bonda, Lingaraj Nayak, Sadhana Kannan, Vikram Gota, Navin Khattry, Indraneel Mittra
Publikováno v: PLoS ONE, Vol 17, Iss 2, p e0262212 (2022)
PLoS ONE
Background Transplant related toxicity is a major therapeutic challenge. We have previously reported that the toxicity of chemotherapy is largely not directly because of the drugs themselves; rather it is mainly due to DNA damage, apoptosis and hyper
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a445976c359b73df1c591f8a8994920
https://doaj.org/article/f152dab89d3b449491212da2ac9f526b
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5
Unsupervised discovery of dynamic cell phenotypic states from transmitted light movies
Autor: Hao Yuan Kueh, Sylvia Chien, Raymond J. Monnat, Phuc H.B. Nguyen, Pamela S. Becker, Jin Dai
Publikováno v: PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 12, p e1009626 (2021)
Identification of cell phenotypic states within heterogeneous populations, along with elucidation of their switching dynamics, is a central challenge in modern biology. Conventional single-cell analysis methods typically provide only indirect, static
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2eb6a168f7871d7ab233557f0251338
http://europepmc.org/articles/PMC8754342
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6
Binary matrix factorization on special purpose hardware
Autor: Osman Asif Malik, Hayato Ushijima-Mwesigwa, Arnab Roy, Avradip Mandal, Indradeep Ghosh
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 12, p e0261250 (2021)
Many fundamental problems in data mining can be reduced to one or more NP-hard combinatorial optimization problems. Recent advances in novel technologies such as quantum and quantum-inspired hardware promise a substantial speedup for solving these pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74408721b2381520200ba867ddfc10e2
http://europepmc.org/articles/PMC8675762
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7
Clinical manifestations, associated risk factors and treatment outcomes of Chronic Pulmonary Aspergillosis (CPA): Experiences from a tertiary care hospital in Lahore, Pakistan
Autor: Waqas Akram, Muhammad Bilal Ejaz, Syed Azhar Syed Sulaiman, Amer Hayat Khan, Tauqeer Hussain Mallhi
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259766 (2021)
Background Chronic pulmonary aspergillosis (CPA) has a wide spectrum of illnesses depending on the progression of the disease and comorbid conditions. However, there is an inadequacy of investigations regarding clinical, laboratory, risk factor and p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0648a00a85150991b6a1d188ecfd008
http://europepmc.org/articles/PMC8589179
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8
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity
Autor: Carlos Farkas, Katharina Haigh, Danny Huylebroeck, Nicholas C. Wong, Catherine Carmichael, Thomas Brabletz, Geert Berx, Simone Brabletz, Marc P. Stemmler, Aissa Benyoucef, Christian M. Nefzger, Steven Goossens, Jody J. Haigh, Jose M. Polo, Jueqiong Wang
Publikováno v: PLoS Biology, Vol 19, Iss 9, p e3001394 (2021)
PLoS Biology, 19(9):e3001394. Public Library of Science
PLoS Biology
PLOS BIOLOGY
The ZEB2 transcription factor has been demonstrated to play important roles in hematopoiesis and leukemic transformation. ZEB1 is a close family member of ZEB2 but has remained more enigmatic concerning its roles in hematopoiesis. Here, we show using
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e053b701583621709b9713e9c139ae
http://www.scopus.com/inward/record.url?scp=85116043345&partnerID=8YFLogxK
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10
In-hospital mortality among immunosuppressed patients with COVID-19: Analysis from a national cohort in Spain
Autor: Suárez-García, Inés, Perales-Fraile, Isabel, González-García, Andrés, Muñoz-Blanco, Arturo, Manzano, Luis, Fabregate, Martín, Díez-Manglano, Jesús, Aizpuru, Eva Fonseca, Fernández, Francisco Arnalich, García, Alejandra García, Gómez-Huelgas, Ricardo, Ramos-Rincón, José-Manuel, SEMI-COVID-19 Network
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255524 (2021)
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
BackgroundWhether immunosuppressed (IS) patients have a worse prognosis of COVID-19 compared to non-IS patients is not known. The aim of this study was to evaluate the clinical characteristics and outcome of IS patients hospitalized with COVID-19 com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f059078dfa044e193943863373015cf
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0255524&type=printable
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