Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hemat S. Khalaf"'
Autor:
Asmaa F. Kassem, Gaber O. Moustafa, Eman S. Nossier, Hemat S. Khalaf, Marwa M. Mounier, Suliman A. Al-Yousef, Sabry Y. Mahmoud
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1247-1258 (2019)
A series of N1,N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16 were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds 4–16 was assessed by the MTT assay method
Externí odkaz:
https://doaj.org/article/ae3a3224d3d242d68f95da0ad4e3d80d
Autor:
Hemat S. Khalaf, Ahmed M. Naglah, Mohamed A. Al-Omar, Gaber O. Moustafa, Hassan M. Awad, Ahmed H. Bakheit
Publikováno v:
Molecules, Vol 25, Iss 16, p 3589 (2020)
Within a series of dipeptide derivatives (5–11), compound 4 was refluxed with d-glucose, d-xylose, acetylacetone, diethylmalonate, carbon disulfide, ethyl cyanoacetate, and ethyl acetoacetate which yielded 5–11, respectively. The candidates 5–1
Externí odkaz:
https://doaj.org/article/c3ea61ad711245099bb04b2f1a6b5fc7
Autor:
Wael A. El-Sayed, Hala E. M. Tolan, M. N. El-Bayaa, Hemat S. Khalaf, M. El-Manawaty, Mohamed A. A. Radwan
Publikováno v:
Russian Journal of General Chemistry. 90:1706-1715
New sugar hydrazones and their derived oxadiazolyl acyclic nucleoside analogs in addition to the derived thioglycosides incorporating pyridine, furan or thiophene have been synthesized via a multi-component reaction (MCR). The acetylated derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2da08bf120b868520adbff1e0da708
https://doi.org/10.1134/s1070363220090182
https://doi.org/10.1134/s1070363220090182
Autor:
Hanem M. Awad, Wael A. El-Sayed, Mohamed A. A. Radwan, Hala E. M. Tolan, Hemat S. Khalaf, M. N. El-Bayaa
Publikováno v:
Russian Journal of General Chemistry. 90:1544-1552
New 1,4-bithiazolyl-5-oxopyrrole derivatives have been synthesized via a multicomponent reaction (MCR) and their structures characterized. N1-Phenyl- and N1-amino-substituted 1,2,4-triazole derivatives linked with bithiazolyl-5-oxopyrrole system also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2598f1df05ac4c9ce7062adf9ffd1c9a
https://doi.org/10.1134/s1070363220080241
https://doi.org/10.1134/s1070363220080241
Autor:
Wael A. El-Sayed, Hala E. M. Tolan, Mohamed A. A. Radwan, Ashraf M. Mohamed, Hemat S. Khalaf, Hanem M. Awad
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 39(7)
New 1,3,4-thiadiazole thioglycosides linked to substituted pyrimidines were synthesized via glycosylation of 1,3,4-thiadiazole thiol compounds. Also, novel 1,2,3-triazole derivatives linked to carb...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f0e7a21f0f13a40bb59d6d4ed2670e
https://pubmed.ncbi.nlm.nih.gov/32312171
https://pubmed.ncbi.nlm.nih.gov/32312171
Publikováno v:
Russian Journal of General Chemistry. 87:2444-2453
Novel conjugates of substituted pyridine and carbohydrate moieties linked by 1,2,3-triazoles were synthesized. The propargyl group was introduced by O-propargylation of pyridone derivatives. Attachment of carbohydrate molecules to the substituted pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::504b9778c62263a93050f6fc9bf645d6
https://doi.org/10.1134/s1070363217100279
https://doi.org/10.1134/s1070363217100279
Autor:
Thoraya A. Farghaly, Eman M. H. Abbas, Dina N. Abd El-Shafy, Hemat S. Khalaf, Salwa F. Mohamed
Publikováno v:
Mini reviews in medicinal chemistry. 18(9)
Background Several commercial drugs utilized in the treatment of HSV containing pyrimidine moiety. Because of the ineffectiveness of virus drugs due to the resistance of the patient's immune system, there is a pressing need to prepare new compounds t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242f0a1ffc18587281bd3bfc38f256ad
https://pubmed.ncbi.nlm.nih.gov/29219053
https://pubmed.ncbi.nlm.nih.gov/29219053
Autor:
Gaber O. Moustafa, Ahmed M. Naglah, Hassan M. Awad, Hemat S. Khalaf, Nawal M. Al-Jafshar, Asma S. Al-Wasidi
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 4, p 761 (2018)
Molecules; Volume 23; Issue 4; Pages: 761
Molecules, Vol 23, Iss 4, p 761 (2018)
Molecules; Volume 23; Issue 4; Pages: 761
A series of linear dipeptide derivatives (4–10) were prepared and evaluated as antimicrobial agents via the synthesis of N-(2-(2-hydrazinyl-2-oxoethylamino)-2-oxoethyl) nicotinamide (4). Compound 4 was reacted with 4-chlorobenzaldehyde or 4-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3037f98bc7e92c5ab44c94d52022ad0e
https://doi.org/10.3390/molecules23040761
https://doi.org/10.3390/molecules23040761