Výsledky vyhledávání - "Hemantika Dasgupta"

Akademický článek

Study of association and molecular analysis of human papillomavirus in breast cancer of Indian patients: Clinical and prognostic implication.

Autor: Saimul Islam, Hemantika Dasgupta, Anirban Roychowdhury, Rittwika Bhattacharya, Nupur Mukherjee, Anup Roy, Gautam Kumar Mandal, Neyaz Alam, Jaydip Biswas, Shyamsundar Mandal, Susanta Roychoudhury, Chinmay Kumar Panda

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172760 (2017)

Human papillomavirus (HPV) causes tumors primarily Cervical cancer. Recently, inconsistent reports came up in Breast cancer (BC) too. In India, despite treatment 70,218 BC patients die each year. So, we explored the association of HPV, if any, with B

Externí odkaz: https://doaj.org/article/68aa586d5681406283ffc9848d31014f

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Inhibition of Autotaxin Ameliorates LPA-Mediated Neuroinflammation and Alleviates Neurological Dysfunction in Acute Hepatic Encephalopathy

Autor: Subhasis Roy, Monali Chakrabarti, Hemantika Dasgupta, Ashutosh Mahale, Shraddha Tripathi, Vivek Sharma, Manish Banerjee, Onkar Prakash Kulkarni

Publikováno v: ACS chemical neuroscience. 13(19)

Growing evidence suggests an essential role of neuroinflammation in behavioral abnormalities associated with hepatic encephalopathy (HE). Here, we report the involvement of autotaxin-lysophosphatidic acid (LPA) signaling in HE's pathogenesis. We demo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e822bb1182d3d11d642d3e92aee5ff
https://pubmed.ncbi.nlm.nih.gov/36112416

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Reduction of nuclear Y654‐p‐β‐catenin expression through SH3GL2‐meditated downregulation of EGFR in chemotolerance TNBC: Clinical and prognostic importance

Autor: Md. Saimul Islam, Susanta Roychoudhury, Mukta Basu, Chinmay Kumar Panda, Neyaz Alam, Anup Roy, Hemantika Dasgupta

Publikováno v: Journal of Cellular Physiology. 235:8114-8128

Triple negative breast cancer (TNBC) originates from a less differentiated ductal cell of breast, which is less sensitive to chemotherapy. The chemotolerance mechanism of TNBC has not yet been studied in detail. For this reason, molecular profiles (e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df149fde22ad92d10192f9c6fef90a1f
https://doi.org/10.1002/jcp.29466

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Hypomethylation of mismatch repair genes MLH1 and MSH2 is associated with chemotolerance of breast carcinoma: Clinical significance

Autor: Saimul Islam, Chinmay Kumar Panda, Anup Roy, Neyaz Alam, Susanta Roychoudhury, Hemantika Dasgupta

Publikováno v: Journal of Surgical Oncology. 119:88-100

Background and objectives The aim of the study was to understand the importance of mismatch repair genes MLH1 and MSH2 in chemotolerance and prognosis of breast carcinoma (BC). Methods First, the alterations (deletion/methylation/expression) of MLH1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af2cb9bb1e2eab5f0231a8a1342ccfc
https://doi.org/10.1002/jso.25304

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Induction of HRR genes and inhibition of DNMT1 is associated with anthracycline anti-tumor antibiotic-tolerant breast carcinoma cells

Autor: Md. Saimul Islam, Susanta Roychoudhury, Neyaz Alam, Hemantika Dasgupta, Chinmay Kumar Panda, Anup Roy

Publikováno v: Molecular and Cellular Biochemistry. 453:163-178

The aim of the study was to understand the role of homologous recombination repair (HRR) pathway genes in development of chemotolerance in breast cancer (BC). For this purpose, chemotolerant BC cells were developed in MCF-7 and MDA MB 231 cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fee39b45241432e7ba65317bf089a7d
https://doi.org/10.1007/s11010-018-3442-5

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SKIN MEDIATED HUMAN PAPILLOMAVIRUS INFECTION IN BREAST: A REPORT OF FOUR CASES

Autor: Neyaz Alam, Chinmay Kumar Panda, Gautam Kumar Mandal, Saimul Islam, Anup Roy, Hemantika Dasgupta, Mukta Basu, Susanta Roychoudhury

Publikováno v: Indian Journal of Case Reports. 4:98-102

To address the ambiguity of different modes of human papillomavirus (HPV) transmission in breast, the immunohistochemical expression of two oncoproteins E6/E7 of HPV16 was analyzed in primary breast cancer (BC) and adjacent normal skin of 4 samples.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e067c3ad3997e865afad4888cb8c46f
https://doi.org/10.32677/ijcr.2018.v04.i02.005

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Downregulation of beta-catenin in chemo-tolerant TNBC through changes in receptor and antagonist profiles of the WNT pathway: Clinical and prognostic implications

Autor: Neyaz Alam, Chinmay Kumar Panda, Saimul Islam, Susanta Roychoudhury, Anup Roy, Hemantika Dasgupta, Mukta Basu

Publikováno v: Cellular oncology (Dordrecht). 43(4)

In approximately 30% of triple-negative breast cancer (TNBC) patients a complete pathological response is achieved. However, after neo-adjuvant chemotherapy treatment (NACT) residual tumour cells can be intrinsically resistant to chemotherapy. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e828315408ca0ce1be2a1d94b0cc7f90
https://pubmed.ncbi.nlm.nih.gov/32430683

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Frequent inactivation of MCC/CTNNBIP1 and overexpression of phospho-beta-catenin Y654 are associated with breast carcinoma: Clinical and prognostic significance

Autor: Rittwika Bhattacharya, Saimul Islam, Anup Roy, Neyaz Alam, Hemantika Dasgupta, Susanta Roychoudhury, Chinmay Kumar Panda, Debolina Pal, Rituparna Roy, Nupur Mukherjee, Jaydip Biswas

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1862:1472-1484

Transcriptional activation of β-catenin is a hallmark of Wnt/β-catenin pathway activation. The MCC (Mutated in colorectal cancers) and CTNNBIP1 (catenin, beta interacting protein 1) are two candidate genes which inhibit the transcriptional activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813a4da09e2d0ae84a994cf01171fdce
https://doi.org/10.1016/j.bbadis.2016.05.009

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Phylogenetic analysis of Human papillomavirus 16 variants isolated from Indian Breast cancer patients showed difference in genetic diversity with that of cervical cancer isolates

Autor: Pijush K. Das, Anup Roy, Neyaz Alam, Ranajit Kumar Mondal, Chinmay Kumar Panda, Hemantika Dasgupta, Dipanjana Mazumder, Anirban Roychowdhury, Mukta Basu, Susanta Roychoudhury, Saimul Islam

Publikováno v: Virus research. 243

The genetic variations of HPV16 in Breast Cancer (BC) are not well studied unlike HPV16 in Cervical Cancer (CACX). In this study, the genetic variations of HPV16 in BC were compared with HPV16 in CACX. In sequencing analysis of LCR, E6 and E7 regions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ded325d506ce4cd18a29f7e0831e1f
https://pubmed.ncbi.nlm.nih.gov/28988982

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Study of association and molecular analysis of human papillomavirus in breast cancer of Indian patients: Clinical and prognostic implication

Autor: Chinmay Kumar Panda, Susanta Roychoudhury, Hemantika Dasgupta, Saimul Islam, Anirban Roychowdhury, Nupur Mukherjee, Anup Roy, Shyamsundar Mandal, Rittwika Bhattacharya, Gautam Kumar Mandal, Neyaz Alam, Jaydip Biswas

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172760 (2017)

Objectives Human papillomavirus (HPV) causes tumors primarily Cervical cancer. Recently, inconsistent reports came up in Breast cancer (BC) too. In India, despite treatment 70,218 BC patients die each year. So, we explored the association of HPV, if

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b3369f618ea7cc66d8c3623a64058a
http://europepmc.org/articles/PMC5330495

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