Melanogenesis Inhibitors

Autor: Sulekha Kumari, Steven Tien Guan Thng, Navin Kumar Verma, Hemant K. Gautam

Publikováno v: Acta Dermato-Venereologica, Vol 98, Iss 10, Pp 924-931 (2018)

Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles. These hyperpigmentary skin disorders can significantly impact an individual’s appeara

Externí odkaz: https://doaj.org/article/65f4d5273383433e8a7fc3c56f1dbfe3

Multisampling-based docking reveals Imidazolidinyl urea as a multitargeted inhibitor for lung cancer: an optimisation followed multi-simulation and in-vitro study

Autor: Shaban Ahmad, Vijay Singh, Hemant K. Gautam, Khalid Raza

Publikováno v: Journal of Biomolecular Structure and Dynamics. :1-18

Lung Cancer is one of the deadliest cancers, responsible for more than 1.80 million deaths annually worldwide, and it is on the priority list of WHO. In the current scenario, when cancer cells become resistant to the drug, making it less effective le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ba9016b7e53568ab6143ac4219a63d
https://doi.org/10.1080/07391102.2023.2209673

inPhocus: Current State and Challenges of Phage Research in Singapore

Autor: Navin Kumar Verma, Si Jia Tan, John Chen, Hanrong Chen, Muhammad Hafiz Ismail, Scott A. Rice, Pablo Bifani, Sukumar Hariharan, Vivek Daniel Paul, Bharathi Sriram, Linh Chi Dam, Chia Ching Chan, Peiying Ho, Boon Chong Goh, Shimin Jasmine Chung, Kenneth Choon Meng Goh, Shu Hua Thong, Andrea Lay-Hoon Kwa, Adam Ostrowski, Thet Tun Aung, Halimah Razali, Shermaine W.Y. Low, Mani Shankar Bhattacharyya, Hemant K. Gautam, Rajamani Lakshminarayanan, Thomas Sicheritz-Pontén, Martha R.J. Clokie, Wilfried Moreira, Maurice Adrianus Monique van Steensel

Publikováno v: Phage (New Rochelle)
Verma, N K, Tan, S J, Chen, J, Chen, H, Ismail, M H, Rice, S A, Bifani, P, Hariharan, S, Paul, V D, Sriram, B, Dam, L C, Chan, C C, Ho, P, Goh, B C, Chung, S J, Goh, K C M, Thong, S H, Kwa, A L H, Ostrowski, A, Aung, T T, Razali, H, Low, S W Y, Bhattacharyya, M S, Gautam, H K, Lakshminarayanan, R, Sicheritz-Pontén, T, Clokie, M R J, Moreira, W & Van Steensel, M A M 2022, ' InPhocus : Current State and Challenges of Phage Research in Singapore ', PHAGE: Therapy, Applications, and Research, vol. 3, no. 1, pp. 6-11 . https://doi.org/10.1089/phage.2022.29028.nkv

Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Tec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04edea808200bf93143c9fecdfabb0ac
https://doi.org/10.1089/phage.2022.29028.nkv

Identification of natural inhibitors to inhibit C. acnes lipase through docking and simulation studies

Autor: Akash Pratap Singh, Hemant Arya, Vijay Singh, Pradeep Kumar, Hemant K. Gautam

Publikováno v: Journal of molecular modeling. 28(9)

Acne vulgaris is a common skin disease affecting 80-90% of teenagers worldwide. C. acnes producing lipases are the main virulence factor that catalyzes sebum lipid into free fatty acid that is used for C. acnes growth. Recently, computational biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b31ec79c797e73a0452654c45edd6f2
https://pubmed.ncbi.nlm.nih.gov/36040538

Biogenic Silver Nanoparticles: Evaluation of Their Biological and Catalytic Potential

Autor: Seema Gupta, Somvir Bajar, Hemant K. Gautam, Bhawna Sharma, Pradeep Kumar, IP Singh

Publikováno v: Indian J Microbiol

The biogenic tailoring of silver nanoparticles using plant extract is becoming an attractive approach in the current scenario. Manilkara zapota (MZ) is well known for its antibacterial, hepato-protective, anti-inflammatory, anti-tussive, anti-fungal,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8717756b14b7a3fd4734d122c83a566
https://doi.org/10.1007/s12088-020-00889-0