Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies

Autor: Nayanika Chakraborty, Diksha Jha, Indrajit Roy, Pradeep Kumar, Shailendra Singh Gaurav, Kalisvar Marimuthu, Oon-Tek Ng, Rajamani Lakshminarayanan, Navin Kumar Verma, Hemant K. Gautam

Publikováno v: Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-25 (2022)

Abstract Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of “post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the situation in future, mainly due to the lack of new/next g

Externí odkaz: https://doaj.org/article/8d403c6e400a45f0ba28151369981ff7

Melanogenesis Inhibitors

Autor: Sulekha Kumari, Steven Tien Guan Thng, Navin Kumar Verma, Hemant K. Gautam

Publikováno v: Acta Dermato-Venereologica, Vol 98, Iss 10, Pp 924-931 (2018)

Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles. These hyperpigmentary skin disorders can significantly impact an individual’s appeara

Externí odkaz: https://doaj.org/article/65f4d5273383433e8a7fc3c56f1dbfe3

New insights into acne pathogenesis: Exploring the role of acne-associated microbial populations

Autor: Bipul Kumar, Rajiv Pathak, P. Bertin Mary, Diksha Jha, Kabir Sardana, Hemant K. Gautam

Publikováno v: Dermatologica Sinica, Vol 34, Iss 2, Pp 67-73 (2016)

Acne vulgaris, a prevalent disorder of the skin, is found to increase the incidence of suicidal ideation in acne patients (∼7.1%). This creates a dilemma in the mind whether acne is a life threatening disease among humans. The main inducer for this

Externí odkaz: https://doaj.org/article/ccc33fd09c7441279a36983dfd777cbd

inPhocus: Current State and Challenges of Phage Research in Singapore

Autor: Navin Kumar Verma, Si Jia Tan, John Chen, Hanrong Chen, Muhammad Hafiz Ismail, Scott A. Rice, Pablo Bifani, Sukumar Hariharan, Vivek Daniel Paul, Bharathi Sriram, Linh Chi Dam, Chia Ching Chan, Peiying Ho, Boon Chong Goh, Shimin Jasmine Chung, Kenneth Choon Meng Goh, Shu Hua Thong, Andrea Lay-Hoon Kwa, Adam Ostrowski, Thet Tun Aung, Halimah Razali, Shermaine W.Y. Low, Mani Shankar Bhattacharyya, Hemant K. Gautam, Rajamani Lakshminarayanan, Thomas Sicheritz-Pontén, Martha R.J. Clokie, Wilfried Moreira, Maurice Adrianus Monique van Steensel

Publikováno v: Phage (New Rochelle)
Verma, N K, Tan, S J, Chen, J, Chen, H, Ismail, M H, Rice, S A, Bifani, P, Hariharan, S, Paul, V D, Sriram, B, Dam, L C, Chan, C C, Ho, P, Goh, B C, Chung, S J, Goh, K C M, Thong, S H, Kwa, A L H, Ostrowski, A, Aung, T T, Razali, H, Low, S W Y, Bhattacharyya, M S, Gautam, H K, Lakshminarayanan, R, Sicheritz-Pontén, T, Clokie, M R J, Moreira, W & Van Steensel, M A M 2022, ' InPhocus : Current State and Challenges of Phage Research in Singapore ', PHAGE: Therapy, Applications, and Research, vol. 3, no. 1, pp. 6-11 . https://doi.org/10.1089/phage.2022.29028.nkv

Bacteriophages and phage-derived proteins are a promising class of antibacterial agents that experience a growing worldwide interest. To map ongoing phage research in Singapore and neighboring countries, Lee Kong Chian School of Medicine, Nanyang Tec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04edea808200bf93143c9fecdfabb0ac
https://doi.org/10.1089/phage.2022.29028.nkv

Identification of natural inhibitors to inhibit C. acnes lipase through docking and simulation studies

Autor: Akash Pratap Singh, Hemant Arya, Vijay Singh, Pradeep Kumar, Hemant K. Gautam

Publikováno v: Journal of molecular modeling. 28(9)

Acne vulgaris is a common skin disease affecting 80-90% of teenagers worldwide. C. acnes producing lipases are the main virulence factor that catalyzes sebum lipid into free fatty acid that is used for C. acnes growth. Recently, computational biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b31ec79c797e73a0452654c45edd6f2
https://pubmed.ncbi.nlm.nih.gov/36040538