Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Hemal H Patel"'
Autor:
Young Song, Joseph Leem, Mehul Dhanani, M Dan McKirnan, Yasuhiro Ichikawa, Julie Braza, Elizabeth O Harrington, H Kirk Hammond, David M Roth, Hemal H Patel
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281550 (2023)
Role of blood-based factors in development and progression of heart failure (HF) is poorly characterized. Blood contains factors released during pathophysiological states that may impact cellular function and provide mechanistic insights to HF manage
Externí odkaz:
https://doaj.org/article/72a857b7ce3f4c92a22888e4870cf155
Autor:
Yasuhiro Ichikawa, Alice E Zemljic-Harpf, Zheng Zhang, M Dan McKirnan, Ana Maria Manso, Robert S Ross, H Kirk Hammond, Hemal H Patel, David M Roth
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177660 (2017)
Anthracyclines are chemotherapeutic drugs known to induce heart failure in a dose-dependent manner. Mechanisms involved in anthracycline cardiotoxicity are an area of relevant investigation. Caveolins bind, organize and regulate receptors and signali
Externí odkaz:
https://doaj.org/article/785157a1d7cc406e9698745e0dd63ed3
Autor:
Hongjuan Yu, Wardit Tigchelaar, Debby P Y Koonen, Hemal H Patel, Rudolf A de Boer, Wiek H van Gilst, B Daan Westenbrink, Herman H W Silljé
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80815 (2013)
A kinase interacting protein 1 (AKIP1) is a molecular regulator of protein kinase A and nuclear factor kappa B signalling. Recent evidence suggests AKIP1 is increased in response to cardiac stress, modulates acute ischemic stress response, and is loc
Externí odkaz:
https://doaj.org/article/cfffa75d86364e4ab452dcc487d0ef62
Autor:
Brian P Head, Jason N Peart, Mathivadhani Panneerselvam, Takaakira Yokoyama, Matthew L Pearn, Ingrid R Niesman, Jacqueline A Bonds, Jan M Schilling, Atsushi Miyanohara, John Headrick, Sameh S Ali, David M Roth, Piyush M Patel, Hemal H Patel
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15697 (2010)
The aged brain exhibits a loss in gray matter and a decrease in spines and synaptic densities that may represent a sequela for neurodegenerative diseases such as Alzheimer's. Membrane/lipid rafts (MLR), discrete regions of the plasmalemma enriched in
Externí odkaz:
https://doaj.org/article/e9ff5077de67451e9e57a9790d69abee
Autor:
Elena L. Kopp, Daniel N. Deussen, Raphael Cuomo, Reinhard Lorenz, David M. Roth, Sushil K. Mahata, Hemal H. Patel
Publikováno v:
Cells, Vol 12, Iss 24, p 2786 (2023)
Type 2 diabetes (T2D) has a complex pathophysiology which makes modeling the disease difficult. We aimed to develop a novel model for simulating T2D in vitro, including hyperglycemia, hyperlipidemia, and variably elevated insulin levels targeting mus
Externí odkaz:
https://doaj.org/article/e19c7bd6e49641b7a54de4fd681033b0
Autor:
S. Clare Stanford, Steve Alexander, Giuseppe Cirino, Christopher H. George, Paul A. Insel, Dave Kendall, Yong Ji, Reynold A. Panettieri, Hemal H. Patel, Christopher G. Sobey, Barbara Stefanska, Gary Stephens, Mauro Teixeira, Nathalie Vergnolle, Péter Ferdinandy, Amrita Ahluwalia
Publikováno v:
British Journal of Pharmacology. 180:1191-1196
Autor:
Liping Zeng, D. Scott Herdman, Sung Min Lee, Ailin Tao, Manasi Das, Samuel Bertin, Lars Eckmann, Sushil Mahata, Panyisha Wu, Miki Hara, Ji-Won Byun, Shwetha Devulapalli, Hemal H. Patel, Anthony J.A. Molina, Olivia Osborn, Maripat Corr, Eyal Raz, Nicholas J.G. Webster
Publikováno v:
Diabetes.
In obesity, CD11c+ innate immune cells are recruited to adipose tissue and create an inflammatory state that causes both insulin and catecholamine resistance. We found that ablation of Gnas, the gene that encodes Gαs, in CD11c expressing cells prote
Autor:
Nicholas J.G. Webster, Eyal Raz, Maripat Corr, Olivia Osborn, Anthony J.A. Molina, Hemal H. Patel, Shwetha Devulapalli, Ji-Won Byun, Miki Hara, Panyisha Wu, Sushil Mahata, Lars Eckmann, Samuel Bertin, Manasi Das, Ailin Tao, Sung Min Lee, D. Scott Herdman, Liping Zeng
In obesity, CD11c+ innate immune cells are recruited to adipose tissue and create an inflammatory state that causes both insulin and catecholamine resistance. We found that ablation of Gnas, the gene that encodes Gas, in CD11c expressing cells protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e2b7ac01b347fb16578b3edd89e440
https://doi.org/10.2337/figshare.23151608.v1
https://doi.org/10.2337/figshare.23151608.v1
Autor:
Mazen Odish, Travis Pollema, Angela Meier, Mark Hepokoski, Cassia Yi, Roger Spragg, Hemal H. Patel, Laura E. Crotty Alexander, Xiaoying (Shelly) Sun, Sonia Jain, Tatum S. Simonson, Atul Malhotra, Robert L. Owens
Publikováno v:
Journal of cardiothoracic and vascular anesthesia, vol 37, iss 3
ObjectivesTo determine in patients with acute respiratory distress syndrome (ARDS) on venovenous extracorporeal membrane oxygenation (VV ECMO) whether reducing driving pressure (ΔP) would decrease plasma biomarkers of inflammation and lung injury (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5d3e1501c3359f28b2b6aa00f7c3d7
https://escholarship.org/uc/item/3bp682gq
https://escholarship.org/uc/item/3bp682gq
Autor:
George P. Philipopoulos, John Tat, Adriano Chan, Jingjing Jiang, David Mukai, Tanya Burney, Melody Doosty, Sari Mahon, Hemal H. Patel, Carl W. White, Matthew Brenner, Jangwoen Lee, Gerry R. Boss
Publikováno v:
Clinical toxicology (Philadelphia, Pa.), vol 60, iss 5
Clin Toxicol (Phila)
Clin Toxicol (Phila)
Methyl mercaptan (CH3SH) is a colorless, toxic gas with potential for occupational exposure and used as a weapon of mass destruction. Inhalation at high concentrations can result in dyspnea, hypoventilation, seizures, and death. No specific methyl me