Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hema Unnikannan"'
Autor:
Abdul Wahid Ansari, Manju Nidagodu Jayakumar, Fareed Ahmad, Thenmozhi Venkatachalam, Laila Salameh, Hema Unnikannan, Thesni Raheed, Abdul Khader Mohammed, Bassam Mahboub, Basel K. Al-Ramadi, Qutayba Hamid, Martin Steinhoff, Rifat Hamoudi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Macrolide antibiotic azithromycin is widely used in clinical practice to treat respiratory tract infections and inflammatory diseases. However, its mechanism of action is not fully understood. Given the involvement of the CD27 pathway in the pathophy
Externí odkaz:
https://doaj.org/article/3075eeb31b1f45bfb13c54eb0fc50a91
Autor:
Amjad Ali, Jasmin Shafarin, Rola Abu Jabal, Nour Aljabi, Mohamad Hamad, Jibran Sualeh Muhammad, Hema Unnikannan, Mawieh Hamad
Publikováno v:
FEBS Open Bio, Vol 11, Iss 11, Pp 3101-3114 (2021)
Overexpression of ferritin heavy chain (FTH1) often associates with good prognosis in breast cancer (BCa), particularly in the triple‐negative subtype (triple‐negative breast cancer). However, the mechanism by which FTH1 exerts its possible tumor
Externí odkaz:
https://doaj.org/article/e843f29f65be4130928faaf844b910d1
Copine 3 'CPNE3' is a novel regulator for insulin secretion and glucose uptake in pancreatic β-cells
Autor:
Waseem El-Huneidi, Shabana Anjum, Abdul Khader Mohammed, Hema Unnikannan, Rania Saeed, Khuloud Bajbouj, Eman Abu-Gharbieh, Jalal Taneera
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Copine 3 (CPNE3) is a calcium-dependent phospholipid-binding protein that has been found to play an essential role in cancer progression and stages. However, its role in pancreatic β-cell function has not been investigated. Therefore, we pe
Externí odkaz:
https://doaj.org/article/fc27aecf3585444197c39e2d67476b8f
Autor:
Amjad Ali, Hema Unnikannan, Jasmin Shafarin, Khuloud Bajbouj, Jalal Taneera, Jibran Sualeh Muhammad, Haydar Hasan, Albert Salehi, Samir Awadallah, Mawieh Hamad
Publikováno v:
Endocrine. 76:543-557
Metformin (MF) intake associates with reduced levels of circulating low-density lipoprotein-cholesterol (LDL-C). This has been attributed to the activation of AMPK, which differentially regulates the expression of multiple genes involved in cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c90072672b27b057bf3d6492e952640
https://doi.org/10.1007/s12020-022-03022-x
https://doi.org/10.1007/s12020-022-03022-x
Autor:
Nour Al-Jabi, Amjad Ali, Khuloud Bajbouj, Rola Abu Jabal, Hema Unnikannan, Jasmin Shafarin, Jibran Sualeh Muhammad, Mawieh Hamad
Publikováno v:
International Journal of Biological Sciences
BET bromodomain BRD4 and RAC1 oncogenes are considered important therapeutic targets for cancer and play key roles in tumorigenesis, survival and metastasis. However, combined inhibition of BRD4-RAC1 signaling pathways in different molecular subtypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bea7976a4927441f8fa8447f4fe064
http://europepmc.org/articles/PMC8579449
http://europepmc.org/articles/PMC8579449
Publikováno v:
Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 14:2087-2092
This study examined the status of plasma levels of protein convertase subtilisin/kexin 9 (PCSK9) in association with glucose-and lipid-lowering medications in subjects with type 2 diabetes (T2D).This study comprised 177 diabetics and 115 non-diabetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8065377fe4447fdb98f650a9e6ed9ac1
https://doi.org/10.1016/j.dsx.2020.10.028
https://doi.org/10.1016/j.dsx.2020.10.028
Copine 3 'CPNE3' is a novel regulator for insulin secretion and glucose uptake in pancreatic β-cells
Autor:
Shabana Anjum, Rania Saeed, Eman Abu-Gharbieh, Khuloud Bajbouj, Jalal Taneera, Abdul Khader Mohammed, Hema Unnikannan, Waseem El-Huneidi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Copine 3 (CPNE3) is a calcium-dependent phospholipid-binding protein that has been found to play an essential role in cancer progression and stages. However, its role in pancreatic β-cell function has not been investigated. Therefore, we performed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4781629d2dc9ea1d1a412b4484ba2c
http://europepmc.org/articles/PMC8526566
http://europepmc.org/articles/PMC8526566
Autor:
Mini Sara Abraham, Hema Unnikannan, Samir Awadallah, Amita Attlee, Veena Raigangar, Hayder Hasan, Latifa M. Rashid, Mohamed Madkour
Publikováno v:
Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 13:2541-2547
Aim Oxidative stress (OS) plays a major role in pathogenic mechanisms associated with metabolic syndrome (Mets) yet the main component of Mets contributing most to OS is not well elucidated. Hence, the aim of this study was to investigate the oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c966307435e830dc35f448bc54a910f5
https://doi.org/10.1016/j.dsx.2019.07.010
https://doi.org/10.1016/j.dsx.2019.07.010
Autor:
Amjad Ali, Nour Al-Jabi, Kiran Menon, Mawieh Hamad, Khuloud Bajbouj, Jibran Sualeh Muhammad, Jasmin Shafarin, Betoul Suleiman, Hema Unnikannan
Publikováno v:
Immunobiology. 225:151995
The ability of monocytes to release or sequester iron affects their role in cancer and inflammation. Previous work has shown that while IL-6 upregulates hepcidin synthesis and enhances iron sequestration, E2 reduces hepcidin synthesis and increases i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ca6b7eb0a2a1cf5b3ae4fa7a2ca605
https://doi.org/10.1016/j.imbio.2020.151995
https://doi.org/10.1016/j.imbio.2020.151995