T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

Autor: Adrienn Angyal, PhD, Stephanie Longet, PhD, Shona C Moore, PhD, Rebecca P Payne, DPhil, Adam Harding, MSc, Tom Tipton, PhD, Patpong Rongkard, MSc, Mohammad Ali, MD, Luisa M Hering, MSc, Naomi Meardon, MBChB, James Austin, PhD, Rebecca Brown, PhD, Donal Skelly, PhD, Natalie Gillson, BSc, Sue L Dobson, MSc, Andrew Cross, PhD, Gurjinder Sandhar, MSc, Jonathan A Kilby, MSc, Jessica K Tyerman, BSc, Alexander R Nicols, MSc, Jarmila S Spegarova, PhD, Hema Mehta, DPhil, Hailey Hornsby, MSc, Rachel Whitham, MSc, Christopher P Conlon, ProfPhD, Katie Jeffery, PhD, Philip Goulder, ProfDPhil, John Frater, ProfPhD, Christina Dold, PhD, Matthew Pace, PhD, Ane Ogbe, PhD, Helen Brown, BSc, M Azim Ansari, DPhil, Emily Adland, PhD, Anthony Brown, BSc, Meera Chand, FRCPath, Adrian Shields, PhD, Philippa C Matthews, PhD, Susan Hopkins, PhD, Victoria Hall, PhD, William James, ProfDPhil, Sarah L Rowland-Jones, ProfDM, Paul Klenerman, ProfPhD, Susanna Dunachie, ProfPhD, Alex Richter, ProfPhD, Christopher J A Duncan, DPhil, Eleanor Barnes, ProfPhD, Miles Carroll, ProfPhD, Lance Turtle, PhD, Thushan I de Silva, PhD, Adam Harding, Adam Watson, Adrian Shields, Adrienn Angyal, Ahmed Alhussni, Alex Richter, Alexander Nicols, Alexandra Deeks, Alice Webb-Bridges, Andrew Cross, Ane Ogbe, Anni Jämsén, Anthony Brown, Anu Chawla, Christina Dold, Christopher Duncan, Christopher Conlon, Donal Skelly, Denise O'Donnell, Eleanor Barnes, Emily Adland, Esme Weeks, Gurjinder Sandhar, Hailey Hornsby, Helen Brown, Hema Mehta, Hibatullah Abuelgasim, Huiyuan Xiao, James Austin, Jarmila Spegarova, Jennifer Holmes, Jenny Haworth, Jessica Tyerman, John Frater, Jonathan Kilby, Joseph Cutteridge, Katie Jeffery, Katy Lillie, Lance Turtle, Leigh Romaniuk, Lucy Denly, Luisa Hering, M. Azim Ansari, Matthew Pace, Meera Chand, Miles Carroll, Mohammad Ali, Mwila Kasanyinga, Naomi Meardon, Natalie Gillson, Patpong Rongkard, Paul Klenerman, Philip Goulder, Philippa Matthews, Rachel Whitham, Rebecca Brown, Rebecca Payne, Robert Wilson, Sarah Rowland-Jones, Sarah Thomas, Shona Moore, Siobhan Gardiner, Stephanie Longet, Stephanie Tucker, Sue Dobson, Susan Hopkins, Susanna Dunachie, Syed Adlou, Thushan de Silva, Tom Tipton, Victoria Hall, William James, Allan Lawrie, Nikki Smith, Helena Turton, Amira Zawia, Martin Bayley, Alex Fairman, Kate Harrington, Rosemary Kirk, Louise Marsh, Lisa Watson, Steven Wood, Benjamin Diffey, Chris Jones, Lauren Lett, Gareth Platt, Krishanthi Subramaniam, Daniel Wootton, Brendan Payne, Sophie Hambleton, Sinead Kelly, Judith Marston, Sonia Poolan, Dianne Turner, Muzlifah Haniffa, Emily Stephenson, Sandra Adele, Hossain Delowar Akhter, Senthil Chinnakannan, Catherine de Lara, Timothy Donnison, Carl-Philipp Hackstein, Lian Lee, Nicholas Lim, Tom Malone, Eloise Phillips, Narayan Ramamurthy, Nichola Robinson, Oliver Sampson, David Eyre, Beatrice Simmons, Lizzie Stafford, Alexander Mentzer, Ali Amini, Carolina Arancibia-Cárcamo, Nicholas Provine, Simon Travis, Stavros Dimitriadis, Sile Johnson, Sarah Foulkes, Jameel Khawam, Edgar Wellington, Javier Gilbert-Jaramillo, Michael Knight, Maeva Dupont, Emily Horner, James Thaventhiran, Jeremy Chalk

Publikováno v: The Lancet Microbe, Vol 3, Iss 1, Pp e21-e31 (2022)

Summary: Background: Previous infection with SARS-CoV-2 affects the immune response to the first dose of the SARS-CoV-2 vaccine. We aimed to compare SARS-CoV-2-specific T-cell and antibody responses in health-care workers with and without previous SA

Externí odkaz: https://doaj.org/article/d48a073da959456b9ed11417935ce5d7

Superior Performance and Reliability of Double Gate Gaussian Doped Negative Capacitance Junctionless Transistor for 200–500 K

Autor: Hema Mehta, Harsupreet Kaur

Publikováno v: IETE Technical Review. 37:391-401

In this work, performance of Double Gate Gaussian Doped Negative Capacitance Junctionless Transistor (DGGDNCJLT) has been studied for temperature range 200–500 K to explore the suitability of the d...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cadd8b7b6abc6e5654aab5c5a44ceac8
https://doi.org/10.1080/02564602.2019.1642149

T-Cell and Antibody Responses to First BNT162b2 Vaccine Dose in Previously SARS-CoV-2-Infected and Infection-Naive UK Healthcare Workers: A Multicentre, Prospective, Observational Cohort Study

Autor: Adrienn Angyal, Stephanie Longet, Shona Moore, Rebecca P. Payne, Adam Harding, Tom Tipton, Patpong Rongkard, Mohammad Ali, Luisa M. Hering, Naomi Meardon, James Austin, Rebecca Brown, Donal Skelly, Natalie Gillson, Sue L. Dobson, Andrew Cross, Gurjinder Sandhar, Jonathan A. Kilby, Jessica K. Tyerman, Alexander R. Nicols, Jarmila S. Spegarova, Hema Mehta, Hailey Hornsby, Rachel Whitham, Christopher P. Conlon, Katie Jeffery, Philip Goulder, John Frater, Christina Dold, Matthew Pace, Ane Ogbe, Helen Brown, Azim M. Ansari, Emily Adland, Anthony Brown, Meera A. Chand, Adrian Shields, Philippa Matthews, Susan Hopkins, Victoria Jane Hall, William James, Sarah L. Rowland-Jones, Paul Klenerman, Susanna Dunachie, Alex G. Richter, Christopher J. A. Duncan, Eleanor Barnes, Miles W. Carroll, Lance Turtle, Thushan I. de Silva, PITCH Consortium

Publikováno v: SSRN Electronic Journal.

Background: Following a single dose of BNT162b2 mRNA vaccine, higher antibody titres are observed following prior SARS-CoV-2 infection than in infection-naive individuals, but T-cell responses are less well defined. Methods: We sampled healthcare wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0876bc0633e1a469a206c1b5e90e99d0
https://doi.org/10.2139/ssrn.3812375

Human MAIT Cell Activation In Vitro

Autor: Nicholas M. Provine, Joachim Hagel, Christian B. Willberg, Carl-Philipp Hackstein, Lucy C. Garner, Paul Klenerman, Matthew Bilton, Ali Amini, Tianqi Leng, Prabhjeet Phalora, Matthew Edmans, Hema Mehta, Hossain Delowar Akther

Publikováno v: Methods in Molecular Biology ISBN: 9781071602065

Item description: Chapter 7 in book 'MAIT Cells' (2020), ed H Kaipe and I Magalhaes. Methods in Molecular Biology, volume 2098. Mucosal-associated invariant T (MAIT) cells are an abundant innate-like T cell subset in humans, enriched in mucosal tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac90e68144b0c11388d7b3a9e301a50
https://pubmed.ncbi.nlm.nih.gov/31792818

Impact of interface layer and metal workfunction on device performance of ferroelectric junctionless cylindrical surrounding gate transistors

Autor: Hema Mehta, Harsupreet Kaur

Publikováno v: Superlattices and Microstructures. 111:194-205

In this work, the negative capacitance phenomenon exhibited by ferroelectric materials has been incorporated in Junctionless Cylindrical Surrounding Gate (JLCSG) transistor and an analytical model has been developed to study the electrical characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4ac583e63821d6a6b33edcf5ef7cfc4
https://doi.org/10.1016/j.spmi.2017.06.032