Spinal autofluorescent flavoprotein imaging in a rat model of nerve injury-induced pain and the effect of spinal cord stimulation.

Autor: Joost L M Jongen, Helwin Smits, Tiziana Pederzani, Malik Bechakra, Mehdi Hossaini, Sebastiaan K Koekkoek, Frank J P M Huygen, Chris I De Zeeuw, Jan C Holstege, Elbert A J Joosten

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109029 (2014)

Nerve injury may cause neuropathic pain, which involves hyperexcitability of spinal dorsal horn neurons. The mechanisms of action of spinal cord stimulation (SCS), an established treatment for intractable neuropathic pain, are only partially understo

Externí odkaz: https://doaj.org/article/8759699e8e824cfd9fb403c30dc1bf57

Experimental Spinal Cord Stimulation and Neuropathic Pain: Mechanism of Action, Technical Aspects, and Effectiveness

Autor: Jan Holsheimer, Helwin Smits, Elbert A.J. Joosten, Maarten van Kleef

Publikováno v: Pain Practice. 13:154-168

Spinal cord stimulation (SCS) is a valuable treatment for chronic intractable neuropathic pain. Although SCS has gone through a technological revolution over the last four decades, the neurophysiologic and biochemical mechanisms of action have only b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14b16e395f746db828649a1a4b675c02
https://doi.org/10.1111/j.1533-2500.2012.00579.x

Increased efficacy of early spinal cord stimulation in an animal model of neuropathic pain

Autor: Michiel Truin, Helwin Smits, Maarten van Kleef, Bengt Linderoth, Elbert A.J. Joosten, Sofie Janssen

Publikováno v: European Journal of Pain, 15(2), 111-117. Wiley

Although spinal cord stimulation (SCS) is an established treatment for chronic neuropathic pain, pain relief is still not successful in a large group of patients. We suggest that the success of SCS may be related to the timing of SCS during the devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdc71b9d40123df2738e3955139d61f
https://doi.org/10.1016/j.ejpain.2010.06.002

Spinal cord stimulation induces c-Fos expression in the dorsal horn in rats with neuropathic pain after partial sciatic nerve injury

Autor: Helwin Smits, Maarten van Kleef, Philipp Gobrecht, Wiel Honig, Elbert A.J. Joosten, Job Gerver

Publikováno v: Neuroscience Letters. 450:70-73

Spinal cord stimulation (SCS) is an established treatment for intractable neuropathic pain, especially CRPS-1. The mechanisms of action of SCS have only been partly elucidated and include suppression of the hyper-excitability of the Wide Dynamic Rang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdfe1a4a7e89f53af0c3397cd3aa5e9
https://doi.org/10.1016/j.neulet.2008.11.013

Spinal Autofluorescent Flavoprotein Imaging in a Rat Model of Nerve Injury-Induced Pain and the Effect of Spinal Cord Stimulation

Autor: Tiziana Pederzani, Helwin Smits, Elbert A.J. Joosten, Joost L M Jongen, Malik Bechakra, Sebastiaan K. E. Koekkoek, Mehdi Hossaini, Chris I. De Zeeuw, Frank J P M Huygen, Jan C. Holstege

Publikováno v: PLoS One, 9(10). Public Library of Science
PLoS One (print), 9(10). Public Library of Science
PLOS ONE, 9(10):e109029. Public Library of Science
PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e109029 (2014)

Nerve injury may cause neuropathic pain, which involves hyperexcitability of spinal dorsal horn neurons. The mechanisms of action of spinal cord stimulation (SCS), an established treatment for intractable neuropathic pain, are only partially understo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ed4bb75143fc58482fbb4ce20e156b
https://cris.maastrichtuniversity.nl/en/publications/d794ceef-3c1f-44f6-bd76-ea9871098228